Cough Syncope due to ACE Inhibitor
Abstract
Syncope is defined as a transient loss of consciousness due to sudden temporary decline in cerebral perfusion. Cough syncope is classically seen in middle aged obese men with obstructive pulmonary disease. In patients that use Angiotensin converting enzyme (ACE) inhibitors, a dry persistent cough can emerge due to the side effects of this medication. Seventy years old male patient that use ACE inhibitor for hypertension accepted to the clinic with the complaint of syncope. A bout of coughing has developed during electroencephalography recording and 10 seconds in duration of subcortical like epileptiform discharges were viewed. The ACE inhibitor the patient was receiving was replaced with calcium channel blocker and no complaint was observed during the follow up period.
Keywords
Kaynakça
- Chung CP, Cheng CY, Zivadinov R, Chen WC, Sheng WY, Lee YC, Hu HH, Hsu HY, Yang KY. Jugular venous reflux and plasma endothelin-1 are associated with cough syncope: a case control pilot study; BMC Neurol. 2013;16;13:9.
- Krediet CT, Wieling W. Edward P. Sharpey Schafer was right: evidence for systemic vasodilatation as a mechanism of Europace. 2008;10:486-8. syncope;
- Omboni S, Borghi C. Zofenopril and incidence of cough: a review of published and unpublished data. Ther Clin Risk Manag; 2011;7:459–71.
- Kułakowski P. Syncope update 2013: diagnosis and
- treatment; Kardiol Pol. 2013;71:215-23.
- Gould PA, Krahn AD, Klein GJ, Yee R, Skanes AC, Gula LC. Syncope: A review. Current Opinion in Cardiology. 2006;21:34–41.
- Soteriades ES, Evans JC, Larson MG, Chen MH, Chen L, Benjamin EJ, Levy D. Incidence and prognosis of syncope. N Engl J Med. 2002;347:878- 85.
- Brignole M, Alboni P, Benditt DG, Bergfeldt L, Blanc JJ, Thomsen PE, Gert van Dijk J, et al. Task Force on European Syncope, Society of Kaohsiung J Med Sci.
- El-Osta H, Ashfaq S. Cough-Induced Syncope as an Unusual Manifestation of Pericardial Effusion; Kansas Journal of Medicine. 2008;1:53-5.
- Benditt DG, Samniah N, Pham S, Sakaguchi S, Lu F, Lurie KG, Ermis C. Effect of cough on heart rate and blood pressure in patients with "cough syncope"; Heart Rhythm. 2005;2:807-13.
