Frequency of rotavirus and enteric adenovirus in children with acute gastroenteritis in Halfeti district, Sanliurfa, Turkey
Abstract
Background/Aim: Enteric viruses (rotavirus, adenovirus, norovirus, etc.) have been reported as the most common cause of non-bacterial acute gastroenteritis. Rotavirus can cause severe fluid and electrolyte imbalance and the development of fatal complications during the course of the disease if not diagnosed and treated early. The aim of study was to evaluate the frequency, epidemiological characteristics, clinical and laboratory data of rotavirus and enteric adenovirus agents in children presenting with diarrhea.
Material and Method: The records of patients with diarrhea between ages of 0-12 who applied to Halfeti State Hospital between July 2017 and July 2019 and diagnosed with acute gastroenteritis and whose rotavirus and enteric adenovirus tests (examined by immunochromatographic methods) were requested were evaluated retrospectively. The frequency of rotavirus and adenovirus gastroenteritis, demographic data, clinical status, laboratory findings of these patients; age groups, gender and seasonal distribution were examined. SPSS 25.0 package program was used for statistical analysis.
Results: 640 patients were included in the study. The median age of the patients was 22 months and 57% were male. Rotavirus was detected in 40% of the patients and adenovirus was found in 10.2% of the patients. It was found that the hospitalization rates of children with positive rotavirus were higher than other groups. The children with rotavirus are mostly in winter; children with adenovirus mostly in spring; rotavirus and adenovirus negative children were admitted to the emergency department mostly during the summer months.
Conclusion: Viral agents constitute an important part of acute gastroenteritis in our region. It was found that stool examinations were important in the diagnosis of rotavirus and adenovirus gastroenteritis causing high mortality and morbidity. We think that unnecessary antibiotic use will decrease with appropriate treatment and the incidence of the disease and hospitalization cost burden will decrease with increasing rotavirus vaccination rates for Turkey.
Keywords
acute gastroenteritis,, adenovirus,child,epidemiology,rotavirus
Kaynakça
- 1. Walker CLF, Rudan I, Liu L, et al. Global burden of childhood pneumonia and diarrhoea. Lancet 2013; 381: 1405-1416.
- 2. Kosek M, Bern C, Guerrant RL. The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bull World Health Organ 2003; 81: 197-204.
- 3. WHO 2004 report. Diarrhoeal Diseases (Updated February 2009). http://www.who.int/vaccine_research/diseases/diarrhoeal/en (15/05/2009).
- 4. United Nations. Millenium Development Goals Report. New York; 2005 http://www.un.org/docs/summit2005/MDGBook.pdf (15/05/2009)
- 5. Gülen A, Hacımustafaoğlu M. Çocuklarda akut infeksiyöz gastroenteritlere genel yaklaşım. ANKEM Derg 2013;27(3):147-57.
- 6. Öztürk R. Reovirus ailesi ve diğer gastroenterit virusları. İçinde:Wilke Topçu A, Söyletir G, Doğanay M (editörler). İnfeksiyon hastalıkları ve mikrobiyolojisi cilt 2. İstanbul: Nobel Tıp Kitabevleri; 2002: s. 1224-32.
- 7. Kurugöl Z, Devrim İ. Gastrointestinal enfeksiyonlar. J Pediatr Inf 2014;8:71-81.
- 8. Bayrakçı B, Özütemiz Ö. Postinfeksiyöz irritabl barsak sendromu. Güncel Gastroenteroloji Derg 2009;13(3):153-7.
- 9. Ulusal Mikrobiyoloji Standartları. Akut Sendromik Yaklaşım Rehberi. 2015;1:3-12.
- 10. Kapikian AZ, Hoshino Y, Chanock RM. et al. Field’s Virology. Philadelphia: Lipincott Williams and Wilkins, 2001: p.1787-833.
