Blood pressure limits affecting carotid artery injury: a cross sectional study
Öz
Objective: Although it is well known that high blood pressure causes undesirable effects on carotid arteries, it is not clear as to which threshold value this effect starts. The aim of this study is to evaluate and determine this threshold.
Materials and Methods: This cross-sectional study included a total of 308 individuals in the following groups; Group 1: individuals with systolic blood pressure (SBP) <120 mmHg and diastolic blood pressure (DBP) <80 mmHg (optimal), Group 2: SBP 120-129 mmHg and/or DBP 80-84 mmHg (normal), Group 3: SBP 130-139 mmHg and/or DBP 85-89 mmHg (high-normal), Group 4: SBP 140-159 mmHg and/or DBP 90-99 mmHg, Group 5: SBP 160-179 mmHg and/or DBP 100-109 mmHg, and Group 6: SBP≥180 mmHg and/or DBP≥110 mmHg. Carotid distensibility and elasticity were measured in all groups.
Results: A statistically significant difference was determined between the groups in carotid distensibility and elasticity (p<0.001, for both values). There was no significant difference between groups 2 and 1 (p>0.05), but there was a significant difference between other groups (groups 3-4-5) and group 1 (p<0.05, for all comparisons). SBP>135.5 mmHg started to affect carotid distensibility with 78.2% sensitivity and 74.6% specificity, and DBP>86.5 mmHg with 79.3% sensitivity and 71.6% specificity. Carotid elasticity was seen to be affected by SBP>137.5 mmHg with 80.4% sensitivity and 73.1% specificity, and DBP>88.5 mmHg with 79.1% sensitivity and 73.8% specificity.
Conclusion: Carotid distensibility and elasticity decreases with increasing blood pressure. In individuals with high-normal blood pressure, carotid damage may begin after a certain blood pressure value.
Anahtar Kelimeler
Blood pressure, Carotid artery, , Doppler
Destekleyen Kurum
Başkent Üniversitesi
Proje Numarası
KA19/339
Teşekkür
Dear Editor;
Please find our report entitled “Blood Pressure Limits Affecting Carotid Artery Injury. A Cross Sectional Study”. We hope you will find our report interesting for reviewing and publishing it in your esteemed Journal. This report had not been published before or is not under review elsewhere. None of the paper’s contents have previously published. All authors have read and approved the manuscript. On behalf of all the contributors I will act and guarantor and will correspond with the journal from this point onward. All authors declare that they have no conflicts of interest. The authors have indicated they have no financial relationships relevant to this article to disclose. This study was approved by Baskent University Institutional Review Board and Ethics Committee and supported by Baskent University Research Funding (KA19/339).
Yours sincerely,
Aylin Güneşli MD, Baskent University, Department of Radiology, Yuregir, Adana, Turkey
03-11-2020
Kaynakça
- 1. Benjamin EJ, Muntner P, Alonso A et al. American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association. Circulation. 2019;139:e56-e528.
- 2. Vernon ST, Coffey S, Bhindi R, et al. Increasing proportion of ST elevation myocardial infarction patients with coronary atherosclerosis poorly explained by standard modifiable risk factors. Eur J Prev Cardiol2017;24:1824–1830.
- 3. Rapsomaniki E, Timmis A, George J, et al. Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1.25 million. people. Lancet 2014; 383: 1899–1911.
- 4. Williams B, Mancia G, Spiering W, et al; ESC Scientific Document Group. 2018 ESC/ESH Guidelines for the management of arterial hypertension. Eur Heart J. 2018; 39: 3021-3104.
- 5. Liao D, Arnett DK, Tyroler HA, et al. Arterial stiffness and the development of hypertension. The ARIC study. Hypertension 1999;34:201–206.
- 6. Jaroch J, Łoboz-Grudzień K, Magda S, et al.The Relationship of Carotid Arterial Stiffness and Left Ventricular Concentric Hypertrophy in Hypertension. Adv Clin Exp Med. 2016;25:263-272.
- 7. Tzortzis S, Ikonomidis I, Lekakis J, et al.Incremental predictive value of carotid intima-media thickness to arterial stiffness for impaired coronary flow reserve in untreated hypertensives. Hypertens Res. 2010;33:367-373.
- 8. Stein JH, Korcarz CE, Hurst RT, et al. Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. Endorsed by the Society for Vascular Medicine. J Am Soc Echocardiogr2008;21:93–111.
- 9. Touboul PJ, Hennerici MG, Meairs S, et al. Mannheim carotid intima-media thickness and plaque consensus (2004-2006-2011). An update on behalf of the advisory board of the 3rd, 4th and 5th watching the risk symposia, at the 13th, 15th and 20th European Stroke Conferences, Mannheim, Germany, 2004, Brussels, Belgium, 2006, and Hamburg, Germany, 2011. Cerebrovasc Dis 2012;34:290–296.
- 10. Marlatt KL, Kelly AS, Steinberger J, et al. The influence of gender on carotid artery compliance and distensibility in children and adults. J Clin Ultrasound 2013;41:340–346.
