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Epidemiologic features and treatment outcomes of pediatric pulmonary tuberculosis cases

Cilt: 45 Sayı: 4 27 Aralık 2020
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Epidemiologic features and treatment outcomes of pediatric pulmonary tuberculosis cases

Abstract

Purpose: We here aimed to examine the epidemiologic features and treatment outcomes of pediatric pulmonary tuberculosis cases who were registered to the Adana Tuberculosis Dispensaries. Materials and Methods: Fifty-six pediatric patients aged 0-18 years with the diagnosis of pulmonary tuberculosis were examined retrospectively in terms of demographic data, clinical characteristics and drug susceptibility test results, as well as treatment outcomes. Data were collected through medical record review. Results: The mean age of the patients was 12.84 ± 5.62 years and 46.4% were female. Nine patients (16%) were aged 0-5 years, 4 (7.1%) were aged 5-10 years, 17 (30.3%) were aged 10-15 years and 26 patients (46.4%) were aged 15-18 years. Fourty-eight children was only pulmonary tuberculosis whereas eight possessed characteristics of both pulmonary and extrapulmonary tuberculosis. The most frequent symptoms were prolonged cough (80.3%) and weight loss (73.2%). Drug susceptibility test was performed only 22 patients. Multidrug resistance was determined in one patient. Among the 56 children for whom treatment outcome was documented, 39 (69.6%) were completed treatment, 16 (28.5%) were cured and 1 (1.7%) had treatment failure. Conclusion: It was observed that the signs and symptoms of our patients were compatible with the literature. The epidemiological characterization of pediatric patients with pulmonary tuberculosis helps to provide a better diagnostic approach in this population.

Keywords

Mycobacterium tuberculosis , Pedaitrics , Public health , Pulmonary tuberculosis

Kaynakça

  1. 1- World Health Organization. Global Tuberculosis Report 2018. http://www.who.int/tb/publications/global_report/en/ (date of access 2020 May 01).
  2. 2- Ohene SA, Fordah S, Boni PD. Childhood tuberculosis and treatment outcomes in Accra: a retrospective analysis. BMC Infectious Diseases 2019;19:6-9.
  3. 3- Jahromi MK, Sharifi-Mood B. Pulmonary tuberculosis in children. Int J Infect. 2014;1(3): e21116. http://intjinfection.com/articles/14737.html
  4. 4- Turel O, Kazanci S, Gonen I, Aydogmus C, Karaoglan E, Siraneci R. Paediatric tuberculosis at a referral hospital in Istanbul: Analysis of 250 cases. BioMed Research International 2016;2016:1-6. doi: 10.1155/2016/6896279
  5. 5- Dilen MF, Çelik T, Tolunay O, Çelik U. Clinical features in childhood tuberculosis followed in our clinic. J Pediatr Inf 2018;12(4):e129-e134.
  6. 6- Gencer H, Dalgıç N, Kafadar I, Kabakçı D, Öncül U. Retrospective evaluation of 35 pediatric tuberculosis cases proven by histopathological and/or microbiological analysis. J Pediatr Inf 2015;9:97-101.
  7. 7- Yunda LF, Sepúlveda EV, Herrera KC, Moreno C. Pulmonary tuberculosis in a pediatric reference hospital in Bogota, Colombia. Int J Mycobacteriol 2017;6:258-63.
  8. 8- Gulec SG, Telhan L, Koçkaya T, Erdem E, Bayraktar B, Palanduz A. Description of pediatric tuberculosis evaluated in a referral center in Istanbul Turkey. Yonsei Med J 2012;53(6): 1176-1182.
  9. 9- Bayhan GI, Tanır G, Metin O, Şimsek H, Aydın-Teke T, Öz FN et al. Pediatric tuberculosis in Turkey: a review of 8-years period in a tertiary care hospital. The Turkish Journal of Pediatrics 2015;57:431-438.
  10. 10- Kamer I, Sütçü M, Acar M, Erol OB, Hançerli Törün S, Salman N et al. Pediyatrik tüberküloz: Bir üniversite hastanesinin beş yıllık deneyimi. J Child 2017;17(2):43-49.

Kaynak Göster

MLA
Etiz, Pınar, ve Ali Tanju Altunsu. “Epidemiologic features and treatment outcomes of pediatric pulmonary tuberculosis cases”. Cukurova Medical Journal, c. 45, sy 4, Aralık 2020, ss. 1698-06, doi:10.17826/cumj.780991.