Frequency of functional gastrointestinal disorders in children with juvenile idiopathic arthritis

Sibel Balcı; Rabia Miray Kisla Ekinci; Eray Akay; İlksen Demir; Mahir Serbes; Dilek Doğruel; Derya Altintas; Gökhan Tümgör

doi:10.17826/cumj.783419

EN TR

Frequency of functional gastrointestinal disorders in children with juvenile idiopathic arthritis

Abstract

Purpose: The aim of this study was to compare the frequency of functional gastrointestinal diseases (FGIDs) in juvenile idiopathic arthritis (JIA) patients with healthy control children. Materials and Methods: This case-control study includes 193 children with JIA followed-up between October 2012 to April 2019 and 139 healthy control children. Demographic features, disease characteristics, treatment modalities were collected retrospectively. Laboratory parameters were recorded at the study enrollment. FGIDs diagnosis were assessed by utilizing Rome IV criteria. Gender, age at disease onset, laboratory parameters, treatment modalities, and clinical status of the disease were compared between the groups. Results: The mean age at study enrollment was 12.05±4.05 and 9.01±3.97 years in children with JIA and healthy control group, respectively. The frequency of FGIDs was significantly higher in JIA patients (13.7%, n=19) than in healthy control group (21.8%, n=42). There was no statistical significance between JIA patients and healthy control group in terms of FGIDs subtypes. Demographic and clinical parameters did not differ between JIA patients grouped according to FGIDs presence. Conclusion: FGIDs is more frequent in JIA patients than healthy controls. Further studies are needed to support our results.

Keywords

Juvenile idiopathic arthritis , Functional gastrointestinal disorders , Irritable bowel syndrome , Functional dyspepsia , Functional constipation

Juvenil idiyopatik artritli çocuklarda fonksiyonel gastrointestinal hastalıkların sıklığı

Öz

Amaç: Bu çalışmada juvenil idiyopatik artriti (JIA) olan çocuklarda fonksiyonel gastrointestinal hastalıklar (FGH) görülme sıklığının sağlıklı çocuklarla karşılaştırması amaçlanmıştır. Gereç ve Yöntem: Bu vaka-kontrol çalışması Ekim 2012 ve Nisan 2019 tarihleri arasında izlemde olan JIA tanılı 193 çocuk ve 139 sağlıklı kontrol çocuk içermektedir. Demografik özellikler, hastalık karakteristikleri, tedavi yaklaşımları geriye dönük olarak toplandı. Çalışma yürütüldüğü esnada laboratuvar parametreleri kaydedildi. FGH tanısı Roma IV kriterlerine göre değerlendirildi.. Cinsiyet, hastalık başlangıç yaşı, laboratuvar parametreleri, tedavi yaklaşımları ve hastalığın klinik durumu iki grup arasında karşılaştırıldı. Bulgular: Çalışma esnasında ortalama yaş JIA hastalarında 12,05±4,05 yıl ve kontrol grubunda 9,01±3,97 yıl idi. FGH hastalık sıklığı JIA hastalarında (%21,8 n=42) kontrol grubuna göre (%13,7, n=19) anlamlı düzeyde yüksekti. FGH subtipleri açısından JIA hastaları ve kontrol grup arasında istatistiksel anlamlılık yoktu. Demografik ve klinik parametreler FGH varlığına göre gruplandırılan JIA hastaları arasında farklı değildi. Sonuç: JIA hastalarında kontrol grubuna göre FGH daha sık görülmektedir. Sonuçlarımızın destekleyici daha fazla çalışmaya ihtiyaç duyulmaktadır.

Anahtar Kelimeler

juvenil idiyopatik artrit , fonksiyonel gastrointestinal hastalıklar , irritabl barsak sendromu , fonksiyonel dispepsi , fonksiyonel konstipasyon

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Çocuk Sağlığı ve Hastalıkları , Gastroenteroloji ve Hepatoloji , Romatoloji ve Artrit

Bölüm

Araştırma Makalesi

Yazarlar

Sibel Balcı ^*
0000-0003-0099-313X
Türkiye

Rabia Miray Kisla Ekinci
0000-0001-6234-822X
Türkiye

Eray Akay Bu kişi benim
0000-0002-9457-283X
Türkiye

İlksen Demir Bu kişi benim
0000-0002-6455-2459
Türkiye

Mahir Serbes Bu kişi benim
0000-0001-6422-2639
Türkiye

Dilek Doğruel Bu kişi benim
0000-0003-3972-7277
Türkiye

Derya Altintas
0000-0003-2090-5248
Türkiye

Gökhan Tümgör
0000-0002-3919-002X
Türkiye

Yayımlanma Tarihi

27 Aralık 2020

Gönderilme Tarihi

23 Ağustos 2020

Kabul Tarihi

6 Ekim 2020

Yayımlandığı Sayı

Yıl 2020 Cilt: 45 Sayı: 4

DOI

https://doi.org/10.17826/cumj.783419

IZ

https://izlik.org/JA42UX92DN

MLA

Balcı, Sibel, vd. “Frequency of functional gastrointestinal disorders in children with juvenile idiopathic arthritis”. Cukurova Medical Journal, c. 45, sy 4, Aralık 2020, ss. 1768-74, doi:10.17826/cumj.783419.

Bu eser Creative Commons Atıf-Gayriticari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

Frequency of functional gastrointestinal disorders in children with juvenile idiopathic arthritis

Abstract

Keywords

Juvenil idiyopatik artritli çocuklarda fonksiyonel gastrointestinal hastalıkların sıklığı

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster