Evaluation of gynecological complaints of women having inflammatory changes in their cervicovaginal smears
Abstract
Purpose: Inflammatory Pap-test is reported commonly, however, there is no consensus on its clinical significance. This study was to investigate the presence of gynecological complaints such as vaginal discharge, pruritus, burning, odor, and pelvic/abdominal pain in women who are having inflammatory changes in their cervicovaginal smears.
Materials and Methods: The cervicovaginal smears of 854 women, between the ages of 18 and 76 (38.7 ± 11.18) years, were evaluated. Papanicolaou staining was used for cytological evaluation. For the diagnosis of inflammation, polymorphonuclear leucocytes (PMNLs) were counted in at least five visual fields (×100). PMNLs counts “above 40” were recorded as inflammation positive.
Results: Inflammation was detected in 115 of the 854 (13.5%) patients; these were considered the study group. Cytological specimens with various types of infections and epithelial cell abnormalities were excluded from the cohort (n = 221, 25.8%). Patients without any infection (n = 518, 60.7%) were accepted as the control group. In the study group, gynecological complaints including vaginal discharge, pruritus, burning, odor, and abdominal pain were found at rates of 56.5%, 6.1%, 3.5%, 4.3%, and 7.8%, respectively. The presence of vaginal discharge was statistically significant in women with inflammation (56.5%) compared to the control group (25.9%).
Conclusion: Vaginal discharge is significantly more frequent in women with inflammatory changes in their cervicovaginal smears.
Keywords
Inflammation , Papanicolaou staining , vaginal discharge , cervicovaginal smears
Kaynakça
- 1. Eckert LO, Koutsky LA, Kiviat NB, Krone MR, Stevens CE, Eschenbach DA. The inflammatory papanicolaou smear: What does it mean? Obstet Gynecol. 1995;86:360-6.
- 2. Beghini J, Giraldo PC, Eleutério J, Amaral RL do, Polpeta NC, Gonçalves AK. Vaginal inflammation: Association between leukocyte concentration and levels of immune mediators. Am J Reprod Immunol. 2016;75:126-33.
- 3. Baka S, Tsirmpa I, Chasiakou A, Tsouma I, Politi E, Gennimata V, et al. Inflammation on the cervical papanicolaou smear: evidence for infection in asymptomatic women? Infect Dis Obstet Gynecol. 2013;2013:184302.
- 4. Ayres de Campos D, Nogueira A, Magalhães F, Bayer P, Monteiro J, Lameirão A, et al. Células inflamatórias na citologia cervicovaginal. Um achado tradutor de infecção? [Inflammatory smears in cervicovaginal cytology. A finding meaning infection?]. Acta Med Port. 1997;10:637-41.
- 5. Bertolino JG, Rangel JE, Blake RL Jr, Silverstein D, Ingram E. Inflammation on the cervical papanicolaou smear: The predictive value for infection in asymptomatic women. Fam Med. 1992;24:447-52.
- 6. Anderson MR, Klink K, Cohrssen A. Evaluation of Vaginal Complaints. JAMA. 2004;291:1368-79.
- 7. von Glehn MP, Sidon LU, Machado ER. Gynecological complaints and their associated factors among women in a family health-care clinic. J Family Med Prim Care. 2017;6:88-92.
- 8. Spence D, Melville C. Vaginal discharge. BMJ. 2007;335:1147-51.
- 9. Schwebke JR. Vaginal Discharge In: Jeffrey D. Klausner, MD, Edward W. Hook III, MD, editors. Current Diagnosis and Treatment of Sexually Transmitted Diseases. New York: McGraw-Hill Medical; 2007.
- 10. Hammond R. Gynaecological causes of abdominal pain. Women's Health Medicine. 2006;3:124-7.
