Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias

Fatih Çölkesen; Yakup Alsancak; Hülya Vatansev; Fatma Çölkesen; Esma Kepenek

EN TR

Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias

Abstract

Purpose: Electrocardiography (ECG) is the first-line diagnostic tool to evaluate cardiac involvement in any disease and COVID-19 patients. The objective of this study is to investigate the ventricular arrhythmia forming effect of COVID-19 and to guide the treatment. Materials and Methods: A total of 74 patients (mean age 52.63±17.85 years) under follow-up for asymptomatic COVID-19 and 74 healthy volunteers (mean age 50.71±6.02 years) were enrolled in the study. Heart rate, QRS duration, QT distance, T-wave morphology (Tp-e interval), Tp-e/QT ratio, and index of cardio-electrophysiological balance (iCEB) were analyzed and compared to both groups. Results: The heart rate was higher, and the QT interval was shorter on ECG in the COVID-19 group. QTc interval, Tp-e intervals, and Tp-e/QT ratio were not different between groups. Furthermore, iCEB and iCEB-c values were not different between groups. A significant positive but weak correlation was observed between CRP and troponin values in patients with COVID-19. Moreover, there was no correlation between troponin levels and Tp-e/QT ratio and iCEB in patients with COVID-19. Conclusion: The chronic cardiac effects of the COVID-19 have not been elucidated. Prospective clinical trials with long-term and a high number of patient populations are needed to reveal this. Notably, patients with significantly elevated troponin values should be followed up for long-term development of cardiomyopathy and arrhythmias.

Keywords

Arrhythmia , COVID-19 , Electrocardiography , iCEB , Tp-e/QT

Asemptomatik COVID-19 ve ventriküler aritmiler arasındaki ilişkinin belirlenmesi

Öz

Amaç: Elektrokardiyografi (EKG), herhangi bir hastalıkta ve COVID-19 hastalarında kardiyak tutulumu değerlendirmek için ilk seçenek tanı aracıdır. Bu çalışmanın amacı, COVID-19'un ventriküler aritmilere yatkınlık oluşturan etkisini araştırmak ve tedaviye rehberlik etmektir. Gereç ve Yöntem: Asemptomatik COVID-19 nedeniyle takip edilen 74 hasta (ortalama yaş 52.63 ± 17.85 yıl) ve 74 sağlıklı gönüllü (ortalama yaş 50.71 ± 6.02 yıl) çalışmaya dahil edildi. Kalp hızı, QRS süresi, QT mesafesi, T dalgası morfolojisi (Tp-e aralığı), Tp-e / QT oranı ve kardiyak elektrofizyolojik denge indeksi (iCEB) analiz edildi ve her iki grup arasında karşılaştırıldı. Bulgular: COVID-19 grubunda EKG'de kalp hızı daha yüksekti ve QT aralığı daha kısaydı. QTc aralığı, Tp-e aralıkları ve Tp-e / QT oranı açısından gruplar arasında farklılık yoktu. Ayrıca, iCEB ve iCEB-c değerleri gruplar arasında farklı değildi. COVID-19'lu hastalarda CRP ve troponin değerleri arasında anlamlı ancak zayıf pozitif bir korelasyon gözlendi. COVID-19'lu hastalarda troponin seviyeleri ile Tp-e / QT oranı ve iCEB arasında korelasyon yoktu. Sonuç: COVID-19'un kronik kardiyak etkileri aydınlatılamamıştır. Bunu ortaya çıkarmak için uzun vadeli ve çok sayıda hasta popülasyonu içeren prospektif klinik araştırmalara ihtiyaç vardır. Özellikle, troponin değerleri önemli ölçüde yüksek olan hastalar, uzun süreli kardiyomiyopati ve aritmi gelişimi açısından izlenmelidir

Anahtar Kelimeler

Aritmi , COVID-19 , Elektrokardiyografi , iCEB , Tp-e/QT

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Kalp ve Damar Cerrahisi , Bulaşıcı Hastalıklar

Bölüm

Araştırma Makalesi

Yazarlar

Fatih Çölkesen ^*
0000-0002-6595-1267
Türkiye

Yakup Alsancak
0000-0001-5230-2180
Türkiye

Hülya Vatansev
0000-0002-8382-3904
Türkiye

Fatma Çölkesen
0000-0001-9545-5179
Türkiye

Esma Kepenek
0000-0002-0295-1745
Türkiye

Yayımlanma Tarihi

31 Mart 2021

Gönderilme Tarihi

28 Ağustos 2020

Kabul Tarihi

4 Ekim 2020

Yayımlandığı Sayı

Yıl 2021 Cilt: 46 Sayı: 1

IZ

https://izlik.org/JA57GJ86BG

MLA

Çölkesen, Fatih, vd. “Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias”. Cukurova Medical Journal, c. 46, sy 1, Mart 2021, ss. 101-7, https://izlik.org/JA57GJ86BG.

Bu eser Creative Commons Atıf-Gayriticari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias

Abstract

Keywords

Asemptomatik COVID-19 ve ventriküler aritmiler arasındaki ilişkinin belirlenmesi

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

IZ

Kaynak Göster