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Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias

Cilt: 46 Sayı: 1 31 Mart 2021
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Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias

Öz

Purpose: Electrocardiography (ECG) is the first-line diagnostic tool to evaluate cardiac involvement in any disease and COVID-19 patients. The objective of this study is to investigate the ventricular arrhythmia forming effect of COVID-19 and to guide the treatment. Materials and Methods: A total of 74 patients (mean age 52.63±17.85 years) under follow-up for asymptomatic COVID-19 and 74 healthy volunteers (mean age 50.71±6.02 years) were enrolled in the study. Heart rate, QRS duration, QT distance, T-wave morphology (Tp-e interval), Tp-e/QT ratio, and index of cardio-electrophysiological balance (iCEB) were analyzed and compared to both groups. Results: The heart rate was higher, and the QT interval was shorter on ECG in the COVID-19 group. QTc interval, Tp-e intervals, and Tp-e/QT ratio were not different between groups. Furthermore, iCEB and iCEB-c values were not different between groups. A significant positive but weak correlation was observed between CRP and troponin values in patients with COVID-19. Moreover, there was no correlation between troponin levels and Tp-e/QT ratio and iCEB in patients with COVID-19. Conclusion: The chronic cardiac effects of the COVID-19 have not been elucidated. Prospective clinical trials with long-term and a high number of patient populations are needed to reveal this. Notably, patients with significantly elevated troponin values should be followed up for long-term development of cardiomyopathy and arrhythmias.

Anahtar Kelimeler

Arrhythmia, COVID-19, Electrocardiography, iCEB, Tp-e/QT

Proje Numarası

Yok

Kaynakça

  1. 1. Huang, C., et al., Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet, 2020. 395(10223): p. 497-506.
  2. 2. Sohrabi, C., et al., World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19). International Journal of Surgery, 2020.
  3. 3. Wang, D., et al., Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA, 2020.
  4. 4. Zhou, P., et al., A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature, 2020. 579(7798): p. 270-273.
  5. 5. Jia, H.P., et al., ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. J Virol, 2005. 79(23): p. 14614-21.
  6. 6. Zhang, H., et al., Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target. Intensive care medicine, 2020: p. 1-5.
  7. 7. Zhou, F., et al., Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet, 2020.
  8. 8. Guo, T., et al., Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19). JAMA Cardiol, 2020.
  9. 9. Seecheran, R., et al., Atrial Arrhythmias in a Patient Presenting With Coronavirus Disease-2019 (COVID-19) Infection. J Investig Med High Impact Case Rep, 2020. 8: p. 2324709620925571.
  10. 10. Kuck, K.H., Arrhythmias and sudden cardiac death in the COVID-19 pandemic. Herz, 2020.

Kaynak Göster

APA
Çölkesen, F., Alsancak, Y., Vatansev, H., Çölkesen, F., & Kepenek, E. (2021). Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias. Cukurova Medical Journal, 46(1), 101-107. https://izlik.org/JA57GJ86BG
AMA
1.Çölkesen F, Alsancak Y, Vatansev H, Çölkesen F, Kepenek E. Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias. Cukurova Med J. 2021;46(1):101-107. https://izlik.org/JA57GJ86BG
Chicago
Çölkesen, Fatih, Yakup Alsancak, Hülya Vatansev, Fatma Çölkesen, ve Esma Kepenek. 2021. “Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias”. Cukurova Medical Journal 46 (1): 101-7. https://izlik.org/JA57GJ86BG.
EndNote
Çölkesen F, Alsancak Y, Vatansev H, Çölkesen F, Kepenek E (01 Mart 2021) Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias. Cukurova Medical Journal 46 1 101–107.
IEEE
[1]F. Çölkesen, Y. Alsancak, H. Vatansev, F. Çölkesen, ve E. Kepenek, “Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias”, Cukurova Med J, c. 46, sy 1, ss. 101–107, Mar. 2021, [çevrimiçi]. Erişim adresi: https://izlik.org/JA57GJ86BG
ISNAD
Çölkesen, Fatih - Alsancak, Yakup - Vatansev, Hülya - Çölkesen, Fatma - Kepenek, Esma. “Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias”. Cukurova Medical Journal 46/1 (01 Mart 2021): 101-107. https://izlik.org/JA57GJ86BG.
JAMA
1.Çölkesen F, Alsancak Y, Vatansev H, Çölkesen F, Kepenek E. Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias. Cukurova Med J. 2021;46:101–107.
MLA
Çölkesen, Fatih, vd. “Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias”. Cukurova Medical Journal, c. 46, sy 1, Mart 2021, ss. 101-7, https://izlik.org/JA57GJ86BG.
Vancouver
1.Fatih Çölkesen, Yakup Alsancak, Hülya Vatansev, Fatma Çölkesen, Esma Kepenek. Evaluation of association between asymptomatic COVID-19 and ventricular arrhythmias. Cukurova Med J [Internet]. 01 Mart 2021;46(1):101-7. Erişim adresi: https://izlik.org/JA57GJ86BG