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Factors predicting prognosis of oncology patients followed in the intensive care unit

Cilt: 45 Sayı: 4 27 Aralık 2020
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Factors predicting prognosis of oncology patients followed in the intensive care unit

Abstract

Purpose: The aim of the study is to determine the factors affecting the mortality of oncology patients followed in the intensive care unit (ICU). Materials and Methods: In this study 100 patients who were followed up in the ICU of Cukurova University Faculty of Medicine, Internal Medicine Department between 2012-2014 were prospectively included. Acute Physiology and Chronic Health Evaluation (APACHE) II, 1st and 3rd day Sequential Organ Failure Assessment Score (SOFA) scores were used to determine the factors that were affecting mortality. Lactate, magnesium, phosphorus, potassium, blood urea nitrogen (BUN) and beta 2 microglobulin levels were determined at the time of admission to ICU. The relationship between vasopressor, renal, respiratory support need, neutropenia, infectious agents and mortality was determined during the follow-up period in the ICU. The patients were divided into two groups as patients transferred from ICU to the inpatient clinics (Group 1: 40 patients) and patients who were died in the ICU follow-up (Group 2: 60 patients). Results: APACHE II and 1st and 3rd day SOFA scores, predictive mortality rate, intensive care admission lactate levels, vasopressor and respiratory support needs, renal support needs, BUN, potassium and magnessium levels, beta 2 microglobulin levels, positive Acinetobacter baumannii culture mean was statistically significant with mortality during intensive care follow up between the Group 1 and 2 patients. In addition, mortality was found to be less in patients followed up in the new ICU. Conclusion: Beta 2 microglobulin level can be used to predict intensive care mortality.

Keywords

Intensive care unit , oncology patients , mortality

Kaynakça

  1. 1. Bouch DC, Thompson JP. Severity scoring systems in the critical ill. Continuing Education in Anesthesia and Critical Care. 2008;8:181-85.
  2. 2. Sakarya M. Yoğun bakımda skorlama sistemleri. Anestezi Yoğun Bakım Ağrı (Ed F Tüzüner):1209-1220. Ankara, Nobel Tıp, 2010.
  3. 3. Holmes CL, Gregoire G, Russell JA. Assessment of severity of illness. Principal of Critical Care. (Eds Hall JB, Schmidt GA, Wood LDH):63-78. New York, The McGraw- Hill Company, 2005.
  4. 4. Higgins TL. Severity of illness indices and outcome prediction. Textbook of Critical Care. (Eds Fink MP, Abraham E, Vincent JL. Kochanek PM):2195-2206. Philadelphia, Elsevier Saunders, 2005.
  5. 5. Cédric A, Régis B, Nicolas F, Delphine D, Bruno F, Olivier B. Plasma beta-2 mıcroglobulın as a marker of fraılty ın older adults: a pılot study. Journal of Gerontology. 2011;66:1077-79.
  6. 6. Bataille R, Grenier J, Sany J. Beta-2-microglobulin in myeloma: optimal use for staging, prognosis, and treatment. A prospective study of 160 patients. Blood. 1984;63:468–76.
  7. 7. Shinkai S, Chaves PH, Fujiwara Y, et al. Beta2-microglobulin for risk stratification of total mortality in the elderly population: comparison with cystatin C and C-reactive protein. Arch Intern Med. 2008;168:200–6.
  8. 8. Cherif H, Martling CR, Hansen J, Klio M, Bjorkholm M. Predictors of short and long term outcome in patients with hematological disorders admitted to the intensive care unit for a life threatining complication. Support Care Cancer. 2007;15:1393-98.
  9. 9. Lamia B, Hellot MF, Girault C, Tamion F, Dachraoui F, Lenain P, Bonmarchand G. Changes in Severity and organ failure scores as prognostic factors in onco-hematological malignancy patients admitted to the ICU. Intensive Care Med. 2006;32:1560-68.
  10. 10. Nichol AD, Egi M, Pettila V, Bellomo R, French C, Hart G et al. Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study. Crit Care. 2010;14-25.

Kaynak Göster

MLA
Oğul, Ali, vd. “Factors predicting prognosis of oncology patients followed in the intensive care unit”. Cukurova Medical Journal, c. 45, sy 4, Aralık 2020, ss. 1267-75, doi:10.17826/cumj.789199.