Evaluation of spontaneous gingival bleeding and related drug withdrawal frequency in atrial fibrillation patients using oral anticoagulants: a case-controlled study

Mustafa Özcan; Hasan Koca

doi:10.17826/cumj.803059

TR EN

Oral antikoagülan kullanan atriyal fibrilasyon hastalarında spontan dişeti kanaması ve ilişkili ilaç bırakma sıklığının değerlendirilmesi: vaka kontrollü çalışma

Öz

Amaç: Bu çalışmanın amacı, oral antikoagülan (OAK) kullanan atriyal fibrilasyon (AF) hastalarında spontan dişeti kanaması (SDK) ve buna bağlı ilaç bırakma sıklığının değerlendirilmesidir. Gereç ve Yöntem: OAK ilaç kullanan 457 AF hastası taranarak spontan dişeti kanaması olan 32 hasta tespit edildi. Bu hastalar, spontan dişeti kanaması olmayan 32 AF hastası ile yaş, cinsiyet ve OAK tedavi protokolü açısından eşleştirilerek periodontal parametreleri karşılaştırıldı. Bulgular: Çalışmaya dahil edilen total popülasyonda, 32 hastada (32/457; % 7.0) SDK saptandı ve bu hastaların 13'ünde (% 40.6) kanamaya bağlı OAK ilaç kullanımını bıraktığı tespit edildi. Plak indeksi (PI), gingival indeks (GI) ve cep derinlikleri (CD) SDK olan hastalarda anlamlı olarak daha yüksek bulundu. Gingival indeksin, hastaların OAK ilacı bırakma riskini bağımsız olarak etkilediği tespit edildi. Sonuç: OAK tedavisi altındaki AF hastalarında, önceden var olan periodontal hastalık nedeniyle önemli oranda SDK ve buna bağlı hastanın OAK ilaç kullanımını bıraktığı gözlendi. Ayrıca gingival indeks skorları, SDK ve OAK ilacın bırakılmasında risk indikatörüdür. OAK tedavisinden önce hastaların periodontal muayenesi ve / veya tedavisi yapılması önerilir.

Anahtar Kelimeler

Atriyal Fibrilasyon , Oral antikoagülan , periodontal hastalık , gingival kanama

Evaluation of spontaneous gingival bleeding and related drug withdrawal frequency in atrial fibrillation patients using oral anticoagulants: a case-controlled study

Abstract

Purpose: The aim of this study was to investigate the frequency of gingival bleeding (GB) and associated drug-withdrawal in atrial fibrillation (AF) patients using oral anti-coagulants (OAC). Materials and Methods: 457 patients with AF receiving OAC were screened. The periodontal parameters and OAC drug-withdrawal of 32 patients with spontaneous GB were compared with 32 patients without bleeding who were matched for age, sex and OAC treatment protocol. Results: GB was detected in 32 patients (7.0%) and 13 of these patients (40.6%) had OAC drug-withdrawal due to bleeding. The plaque index (PI), gingival index (GI) and probing pocket depths (PPD) were significantly higher in patients with GB. The GI scores independently determined the risk of OAC drug-withdrawal. Conclusion: AF patients under OAC treatment may have significant rates of GB and subsequent OAC withdrawal due to pre-existing periodontal disease. The GI scores and GB can predict the risk of OAC drug-withdrawal. The periodontal examination and/or treatment of these patients should be performed before OAC treatment.

Keywords

Atrial fibrillation , oral anti-coagulant therapy , periodontal disease , gingival bleeding

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Kalp ve Damar Cerrahisi , Klinik Tıp Bilimleri

Bölüm

Araştırma Makalesi

Yazarlar

Mustafa Özcan ^*
0000-0002-5562-553X
Türkiye

Hasan Koca
0000-0002-6232-4567
Türkiye

Yayımlanma Tarihi

31 Mart 2021

Gönderilme Tarihi

30 Eylül 2020

Kabul Tarihi

10 Ekim 2020

Yayımlandığı Sayı

Yıl 2021 Cilt: 46 Sayı: 1

DOI

https://doi.org/10.17826/cumj.803059

IZ

https://izlik.org/JA44KG65EL

MLA

Özcan, Mustafa, ve Hasan Koca. “Evaluation of spontaneous gingival bleeding and related drug withdrawal frequency in atrial fibrillation patients using oral anticoagulants: a case-controlled study”. Cukurova Medical Journal, c. 46, sy 1, Mart 2021, ss. 325-31, doi:10.17826/cumj.803059.

Bu eser Creative Commons Atıf-Gayriticari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

Oral antikoagülan kullanan atriyal fibrilasyon hastalarında spontan dişeti kanaması ve ilişkili ilaç bırakma sıklığının değerlendirilmesi: vaka kontrollü çalışma

Öz

Anahtar Kelimeler

Evaluation of spontaneous gingival bleeding and related drug withdrawal frequency in atrial fibrillation patients using oral anticoagulants: a case-controlled study

Abstract

Keywords

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster