Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions

Mesut Ozturk; Aslı Tanrıvermiş Sayıt; Cetin Çelenk; Volkan Yeter

doi:10.17826/cumj.994078

TR EN

Benign ve malign orbital lezyonların ayrımında difüzyon ağırlıklı MRG ve konvansiyonel MRG’nin tanısal değeri

Öz

Amaç: Bu çalışmanın amacı benign ve malign orbital lezyonların ayrımında difüzyon ağırlıklı görüntüleme (DAG) ve konvansiyonel manyetik rezonans görüntüleme (MRG)’nin rolünü değerlendirmektir. Gereç ve Yöntem: Orbital lezyonu 43 hasta (27 kadın ve 16 erkek; ortalama yaş: 26,3 ± 28,5), DAG ve konvansiyonel MRG ile değerlendirildi. Lezyonların görünür difüzyon katsayısı (ADC) ölçüldü ve lezyonların maksimum ADC (ADCmaks), ortalama ADC (ADCort), minimum ADC (ADCmin), ADCort değerinin serebral beyaz cevherin ortalama ADC'sine oranı (ADCortoran) ve ADCmin'in serebral beyaz cevherin ortalama ADC’sine oranı (ADCminoran) hesaplandı. Lezyonların T1 ve T2 ağırlıklı görüntüleme özellikleri ve kontrastlanma paternleri de belirlendi. Malign ve benign orbital lezyonların ayrımı için ADC değişkenlerinin ve konvansiyonel MRG özelliklerinin tanısal performansları değerlendirildi. Bulgular: Malign lezyonların ADCort, ADCmin, ADCortoran ve ADCminoran değerleri, benignlerinkinden anlamlı derecede düşüktü. ADCortoran en yüksek tanısal performansa sahipti; 1,27 sınır değer seçildiğinde duyarlılığı ve özgüllüğü %87,5 ve %70,4 bulundu. Benign ve malign lezyonları ayırt etmek için sınır ADCort değeri 0,97 × 10-3 mm2/s seçilmesi, %75 duyarlılık ve %74 özgüllük ortaya çıkardı. Konvansiyonel MRG özellikleri malign tanı ile ilişkili değildi. Sonuç: DAG'den elde edilen ADC değerleri, benign ve malign orbital lezyonların ayrımına katkı sağlamaktadır. Anahtar kelimeler: Difüzyon ağırlıklı görüntüleme, Görünür difüzyon katsayısı, Orbital neoplazi, Manyetik rezonans görüntüleme

Anahtar Kelimeler

Difüzyon ağırlıklı görüntüleme, Görünür difüzyon katsayısı, Orbital neoplazi, Manyetik rezonans görüntüleme

Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions

Öz

Purpose: The aim of this study was to assess the role of diffusion-weighted imaging (DWI) and conventional magnetic resonance imaging (MRI) in the differentiation of benign and malignant orbital lesions. Materials and Methods: 43 patients (27 women and 16 men; mean age: 26.3±28.5) with orbital lesions were assessed with conventional MRI and DWI. The apparent diffusion coefficient (ADC) of the lesions was measured, and maximum ADC (ADCmax), mean ADC (ADCmean), minimum ADC (ADCmin), the ratio of ADCmean to cerebral white matter ADC (ADCmeanratio), and the ratio of ADCmin to cerebral white matter ADC (ADCminratio) were calculated. T1-weighted and T2-weighted imaging features and contrast enhancement patterns were determined. The diagnostic performances of ADC variables and conventional MRI features for the differentiation of benign and malignant orbital lesions were assessed. Results: ADCmean, ADCmin, ADCmeanratio, and ADCminratio of the malignant lesions were significantly lower than those of the benign ones . ADCmeanratio had the highest diagnostic performance with a sensitivity and specificity of 87.5% and 70.4% at a threshold of 1.27. Selecting a cut-off ADCmean of 0.97 × 10-3 mm2/s for differentiating benign and malignant lesions revealed 75% sensitivity and 74% specificity. Conventional MRI features were not associated with the malignant diagnosis). Conclusion: ADC values obtained from DWI contribute to the differentiation of benign and malignant orbital lesions.

Anahtar Kelimeler

Diffusion-weighted imaging; apparent diffusion coefficient; orbital neoplasm; magnetic resonance imaging

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Klinik Tıp Bilimleri

Bölüm

Araştırma Makalesi

Yazarlar

Mesut Ozturk ^*
0000-0003-4059-2656
Türkiye

Aslı Tanrıvermiş Sayıt
0000-0003-2861-156X
Türkiye

Cetin Çelenk
0000-0002-6078-7525
Türkiye

Volkan Yeter
0000-0002-0357-9009
Türkiye

Yayımlanma Tarihi

31 Mart 2022

Gönderilme Tarihi

11 Eylül 2021

Kabul Tarihi

14 Kasım 2021

Yayımlandığı Sayı

Yıl 2022 Cilt: 47 Sayı: 1

DOI

https://doi.org/10.17826/cumj.994078

IZ

https://izlik.org/JA67ES49MW

APA

Ozturk, M., Tanrıvermiş Sayıt, A., Çelenk, C., & Yeter, V. (2022). Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. Cukurova Medical Journal, 47(1), 34-43. https://doi.org/10.17826/cumj.994078

AMA

1.Ozturk M, Tanrıvermiş Sayıt A, Çelenk C, Yeter V. Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. Cukurova Med J. 2022;47(1):34-43. doi:10.17826/cumj.994078

Chicago

Ozturk, Mesut, Aslı Tanrıvermiş Sayıt, Cetin Çelenk, ve Volkan Yeter. 2022. “Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions”. Cukurova Medical Journal 47 (1): 34-43. https://doi.org/10.17826/cumj.994078.

EndNote

Ozturk M, Tanrıvermiş Sayıt A, Çelenk C, Yeter V (01 Mart 2022) Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. Cukurova Medical Journal 47 1 34–43.

IEEE

[1]M. Ozturk, A. Tanrıvermiş Sayıt, C. Çelenk, ve V. Yeter, “Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions”, Cukurova Med J, c. 47, sy 1, ss. 34–43, Mar. 2022, doi: 10.17826/cumj.994078.

ISNAD

Ozturk, Mesut - Tanrıvermiş Sayıt, Aslı - Çelenk, Cetin - Yeter, Volkan. “Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions”. Cukurova Medical Journal 47/1 (01 Mart 2022): 34-43. https://doi.org/10.17826/cumj.994078.

JAMA

1.Ozturk M, Tanrıvermiş Sayıt A, Çelenk C, Yeter V. Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. Cukurova Med J. 2022;47:34–43.

MLA

Ozturk, Mesut, vd. “Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions”. Cukurova Medical Journal, c. 47, sy 1, Mart 2022, ss. 34-43, doi:10.17826/cumj.994078.

Vancouver

1.Mesut Ozturk, Aslı Tanrıvermiş Sayıt, Cetin Çelenk, Volkan Yeter. Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. Cukurova Med J. 01 Mart 2022;47(1):34-43. doi:10.17826/cumj.994078