Araştırma Makalesi

Association of hematological indices with neurological symptoms in COVID 19 patients

Cilt: 47 Sayı: 2 30 Haziran 2022
Selma Tekin *, Zeynep Ünlütürk , Çağdaş Erdoğan , Esin Avcı , Tugba Sarı , Secil Deniz , Hülya Aybek , Erhan Ugurlu , Murat Seyit , İsmail Hakkı Akbudak
PDF İndir
Cukurova Medical Journal Kapak Cukurova Medical Journal
TR EN

Association of hematological indices with neurological symptoms in COVID 19 patients

Abstract

Purpose: The aim of this study was to compare the neurological involvement in Coronavirus 19 (COVID-19) patients with laboratory findings with these cost-free, practical tests. Materials and Methods: Of the 170 patients diagnosed COVID-19, 103 patients could be reached by phone, and neurological symptoms were recorded as three categories. Laboratory tests of the patients and 103 controls whose real-time polymerase chain reaction (RT-PCR) test negative without any chronic disease history and drug use were obtained from the hospital software. Results: White blood cell, neutrophil, lymphocyte, eosinophil, basophil, platelet were lower, monocyte to lymphocyte ratio and platelet to lymphocyte ratio higher in patients than controls. In the group with central nervous system findings, red blood cell and hematocrit counts, in the group with peripheral nervous system findings, lymphocyte and platelet counts and with sleep disturbances and muscle pain group eosinophil counts were lower in patients than those without. Conclusion: COVID-19 patients with neurological symptoms have some hematological abnormalities. The presence of certain hematological findings may be a clue to the emergence of neurological symptoms, and early detection and correction of these hematological abnormalities may be the solution to prevent the development of neurological symptoms in COVID-19.

Keywords

COVID-19 , neurological symptom , hematological parameters , neutrophil to lymphocyte ratio , monocyte to lymphocyte ratio , platelet to lymphocyte ratio

Kaynakça

  1. 1. Hasöksüz M, Kiliç S, Saraç F. Coronaviruses and sars-cov-2. Turkish J Med Sci 2020;50(SI-1):549-556. doi:10.3906/sag-2004-127
  2. 2. Bostan S, Erdem R, Öztürk YE, Kılıç T, Yılmaz A. The effect of COVID-19 pandemic on the Turkish society. Electron J Gen Med. 2020;17(6). doi:10.29333/ejgm/7944
  3. 3. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395(10223):497-506. doi:10.1016/S0140-6736(20)30183-5
  4. 4. Mao L, Jin H, Wang M, et al. Neurologic Manifestations of Hospitalized Patients with Coronavirus Disease 2019 in Wuhan, China. JAMA Neurol0 2020. doi:10.1001/jamaneurol.2020.1127
  5. 5. Nöroloji C-. Covid-19 and Neurology. 2020;(3):3-5.
  6. 6. Yang AP, Liu J ping, Tao W qiang, Li H ming. The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients. Int Immunopharmacol 2020;84(February):106504. doi:10.1016/j.intimp.2020.106504
  7. 7. Henry BM, De Oliveira MHS, Benoit S, Plebani M, Lippi G. Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in cfile:///C:/Users/Nermine/Downloads/[14374331 - Clinical Chemistry and Laboratory Medicine (CCLM)] Hematologic, biochemical and immune biomarker ab. Clin Chem Lab Med 2020. doi:10.1515/cclm-2020-0369
  8. 8. Guan W, Ni Z, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382(18):1708-1720. doi:10.1056/NEJMoa2002032
  9. 9. Erratum: Covid-19 and long term conditions: What if you have cancer, diabetes, or chronic kidney disease? (BMJ (2020)368 (m1174) DOI: 10.1136/bmj.m1174). BMJ 2020;368(March):2020. doi:10.1136/bmj.m1270
  10. 10. Altunisik, E., Sayiner, H. S., Aksoz, S., Cil, E., Ozgenc, G. Neurological symptoms in COVID-19 patients. Bratislavske Lekarske Listy.2021; 122(1), 39-44.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Klinik Tıp Bilimleri

Bölüm

Araştırma Makalesi

Yazarlar

Yayımlanma Tarihi

30 Haziran 2022

Gönderilme Tarihi

20 Eylül 2021

Kabul Tarihi

14 Mart 2022

Yayımlandığı Sayı

Yıl 2022 Cilt: 47 Sayı: 2

IZ

https://izlik.org/JA57FA45SD

Kaynak Göster

RIS / Bibtex
MLA
Tekin, Selma, vd. “Association of hematological indices with neurological symptoms in COVID 19 patients”. Cukurova Medical Journal, c. 47, sy 2, Haziran 2022, ss. 526-34, https://izlik.org/JA57FA45SD.
Creative Commons Lisansı