Ektopik gebelik ve düşük tehdidi tanısında hemogram parametrelerinin değerlendirilmesi

Year 2021, Volume: 46 Issue: 1, 63 - 69, 31.03.2021

Jule Eriç Horasanlı , Hüseyin Görkemli , Eren Berkay Özkaya Mehmet Murat Işıkalan , Delal Akıncı , Fatma Kılıç

Abstract

Amaç: Bu çalışmanın amacı ektopik gebelik ve düşük tehdidi mevcut olan hastaların hemogram parametrelerini, normal intrauterin gebeliği olan hastalar ile karşılaştırmak, bu parametrelerin ektopik gebelik erken tanısında ve düşük tehdidi ayrımında kullanılabilirliğini araştırmaktır.
Gereç ve Yöntem: Çalışmamız Ocak 2016-Ocak 2019 tarihleri arasında hastanemizde ektopik gebelik tanısı ile medikal ya da cerrahi yolla tedavi edilmiş (n:50), ve düşük tehdidi tanısı ile hospitalize edilmiş hastalar (n:50) ile normal intrauterin gebeliği mevcut olan hastalar (n:50) arasında retrospektif bir araştırma olarak planlandı. Tüm hastaların preoperatif ve hastaneye yatış hemogram kan parametreleri dosyalarından elde edildi. Tüm gruplarda sosyodemografik veriler, tam kan sayımı kaydedildi. Nötrofil lenfosit oranı (NLR), trombosit lenfosit oranı (PLR), lenfosit monosit oranı (LMR) hesaplandı.
Bulgular: Düşük tehdidi ve ektopik gebeliklerde lenfosit sayısı, kontrol grubuna göre daha yüksek olarak saptandı. PDW, ektopik gebeliklerde kontrol grubuna göre anlamlı düzeyde düşük saptandı. Monosit değerleri, düşük tehdidi grubunda kontrol grubuna göre anlamlı olarak daha yüksek bulundu. Düşük tehdidinde PLR kontrol grubuna göre anlamlı olarak daha düşük saptandı.
Sonuç: PDW değerlerinin düşük bulunması ektopik gebelikte mikroçevreyi değiştirerek gebeliğin implantasyonu bozmakla suçlanmaktadır. Mevcut çalışmada PDW değerlerinin ektopik gebelikte düşük bulunması nedeni ile bu parametre kullanılarak, erken tanısında faydalı olabilir.

Keywords

Ektopik gebelik, Düşük tehdidi, Hemogram Parametreleri

Evaluation of hemogram parameters in the diagnosis of ectopic pregnancy and threatened abortion

Abstract

Purpose: The aim of this study is to compare hemogram parameters of patients with the threat of ectopic pregnancy and abortion with those of patients with normal intrauterine pregnancy, and to investigate the utility of these parameters in the diagnosis of ectopic pregnancy and distinction of threatened abortion.
Materials and Methods: This study was planned as a retrospective study including patients diagnosed with ectopic pregrancy who were treated medically or surgically (n: 50), patients diagnosed with normal intrauterine pregnancy (n: 50), and patients hospitalized with the diagnosis of threatened abortion (n:50). Preoperative and during hospitalization hemogram blood parameters of all patients were obtained from their files. Sociodemographic data, complete blood count data were recorded and neutrophyl lymphocyte ratio (NLR) platelet lymphocyte ratio (PLR) and lymphocyte monocyte ratio (LMR) were calculated.
Results: In threatened abortion and ectopic pregnancies, lymphocyte count was found much higher than that of control group. PDW was significantly lower in ectopic pregnancies compared to control group. Monocyte values were significantly higher in threatened abortion group compared to control group. PLR was significantly lower in threatened abortion group compared to control group.
Conclusion: Low PDW values are accused of disrupting pregnancy implantation by changing microenvironment in ectopic pregnancy. Since PDW values were found low in ectopic pregnancy group in our study, it may be useful to use this parameter in early diagnosis.

Keywords

ectopic pregnancy

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