Olgu Sunumu
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Konjenital batın ön duvarı defektleri: 4 yıllık olgu serisi

Yıl 2021, Cilt: 46 Sayı: 3, 1309 - 1314, 30.09.2021
https://doi.org/10.17826/cumj.908437

Öz

Konjenital batın ön duvarı defektleri nadir görülen yapısal anomalilerdir. Bu olguların ve eşlik eden anomalilerin erken saptanması, bebeklerin doğumdan sonra yatırılarak izleminin ve bakımlarının erken başlanması prognozu etkilemektedir. Bu çalışma 4 yıllık süre içinde hastanemizde doğmuş ve yenidoğan yoğun bakım ünitemizde takip edilmiş batın ön duvarı defekti tanılı olguların canlı doğumlar içindeki sıklığını, prenatal tanı oranlarını, demografik ve klinik verilerini incelemek amacıyla yapılmıştır. Haziran-2015 ile Ekim 2019 tarihleri arasında batın ön duvarı defekti tanısı ile yatırılarak izlenen 23 hastanın demografik ve klinik verileri retrospektif olarak incelendi, föy oluşturulduktan sonra hasta dosyaları tarandı. Çalışmamızda hastanemize başvuran batın ön duvarı defektlerinin çoğu doğum sırasında teşhis edilmişti. Antenatal takip edilen sadece 5 olgu prenatal tanı ile yatırılmıştı. Çalışmadaki olguların çoğunluğunu takipsiz gebeliklerden olan bebekler oluşturmuştu. Olguların çoğunluğunu omfaloselli bebekler (%56.5) idi. Olguların toplam mortalite oranı %26.1 idi. Mortalite ve morbiditeyi etkileyen en önemli faktörün eşlik eden anomaliler olduğu görüldü. Batın ön duvarı defekti olan olguların çoğunluğunu omafaloselli hastalar oluşturuyordu. Bu olgularda prenatal tanı oranı oldukça düşüktü. Antenatal takip ve 3.-4. düzey yenidoğan yoğun bakım ünitelerinin olduğu merkezlerde doğumun yaptırılmasının, mortalite ve morbiditeyi azaltmada etkili olacağı düşünüldü.

Destekleyen Kurum

Yok

Proje Numarası

Yok

Teşekkür

Yok

Kaynakça

  • 1. Kastenberg ZJ, Dutta S. Ventral abdominal wall defects. NeoReviews August 2013, 14 (8): e402-e411.
  • 2. Garne E, Loane M, Dolk H, De Vigan C, Scarano G, Tucker D, et al. Prenatal diagnosis of severe structural congenital malformations in Europe. Ultrasound Obstet Gynecol. 2005; 25(1): 6–11
  • 3. Lepigeon K, Van Mieghem T, Vasseur Maurer S, Giannoni E, Baud D. Gastroschisis-what should be told to parents? Prenat Diagn. 2014; 34: 316–26.
  • 4. Chun K, Andrews HG, White JJ. Gastroschisis in successive siblings: further evidence of an acquired etiology. J Pediatr Surg 1993; 28: 838-839
  • 5. Jenkins MM, Reefhuis J, Gallagher ML, Mulle JG, Hoffmann TJ, Koontz DA, et al. Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk. Am J Med Genet. 2014; 164A: 1454– 63.
  • 6. Skarsgard ED. Management of gastroschisis. Curr Opin Pediatr. 2016; 28: 363–9.
  • 7. Raitio A, Lahtinen A, Syvänen J, Kemppainen T, Löyttyniemi E, Gissler M, et al. Gastroschisis in Finland 1993 to 2014-Increasing Prevalence, High Rates of Abortion, and Survival: A Population-Based Study. Eur J Pediatr Surg. 2020; 30(6):536-540.
  • 8. D'Antonio F, Virgone C, Rizzo G, Khalil A, Baud D, Cohen-Overbeek TE, et al. Prenatal risk factors and outcomes in gastroschisis: a meta-analysis. Pediatrics. 2015; 136(1): e159–69.
  • 9. Marshall J, Salemi JL, Tanner JP, Ramakrishnan R, Feldkamp ML, Marengo LK, et al. Prevalence, correlates, and outcomes of Omphalocele in the United States, 1995-2005. Obstet Gynecol. 2015; 126(2): 284–93.
  • 10. Benjamin B, Wilson GN. Registry analysis supports different mechanisms for gastroschisis and omphalocele within shared developmental fields. Am J Med Genet A. 2015; 167A(11): 2568-81.
  • 11. Al-Kaff A, MacDonald SC, Kent N, Burrows J, Skarsgard ED, Hutcheon JA. Delivery planning for pregnancies with gastroschisis: findings from a prospective national registry. Am J Obstet Gynecol. 2015; 213: 557e.1–8.
  • 12. Gamba P, Midrio P. Abdominal wall defects: prenatal diagnosis, newborn management, and long-term outcomes. Semin Pediatr Surg. 2014; 23: 283–90.
  • 13. Bergholz R, Boettcher M, Reinshagen K, Wenke K. Complex gastroschisis is a different entity to simple gastroschisis affecting morbidity and mortality-a systematic review and meta-analysis. J Pediatr Surg. 2014; 49: 1527–32.
  • 14. Lap CC, Brizot ML, Pistorius LR, Kramer WL, Teeuwen IB, Eijkemans MJ, et al. Outcome of isolated gastroschisis; an international study, systematic review and meta-analysis. Early Hum Dev. 2016; 103: 209–18.
  • 15. Corey KM, Hornik CP, Laughon MM, et al. Frequency of anomalies and hospital outcomes in infants with gastroschisis and omphalocele. Early Hum Develop 2014; 90: 421-424.

Congenital anterior abdominal wall defects: 4 years case series

Yıl 2021, Cilt: 46 Sayı: 3, 1309 - 1314, 30.09.2021
https://doi.org/10.17826/cumj.908437

Öz

Congenital anterior abdominal wall defects are rare structural anomalies. Early detection of these cases and associated anomalies, if any and early hospitalization and early care of babies after birth affect the prognosis. This study was conducted to examine the frequency of live births, prenatal diagnosis rates, demographic and clinical data of patients diagnosed with anterior abdominal wall defects who were born in our hospital and followed in our neonatal intensive care unit within a 4-year period. The demographic and clinical data of 23 patients who were hospitalized with the diagnosis of anterior abdominal wall defect between June-2015 and October 2019 were retrospectively analyzed, and patient files were scanned. In this study, most of the anterior abdominal wall defects admitted to our hospital were diagnosed during delivery. Only 5 cases followed antenatally were hospitalized with prenatal diagnosis. Most of the cases in the study consisted of babies from pregnancies without follow-up. The majority of cases were babies with omphalocele (56.5%). The total mortality rate of the cases was 26.1%. Concomitant anomalies were the most important factor affecting mortality and morbidity. The majority of patients with anterior abdominal wall defects were patients with omphalocele. In these cases, the prenatal diagnosis rate was quite low. Close follow up pregnant women in antenatal period and to provide giving births in centers with III-IV level NICU would be effective in reducing mortality and morbidity.

Proje Numarası

Yok

Kaynakça

  • 1. Kastenberg ZJ, Dutta S. Ventral abdominal wall defects. NeoReviews August 2013, 14 (8): e402-e411.
  • 2. Garne E, Loane M, Dolk H, De Vigan C, Scarano G, Tucker D, et al. Prenatal diagnosis of severe structural congenital malformations in Europe. Ultrasound Obstet Gynecol. 2005; 25(1): 6–11
  • 3. Lepigeon K, Van Mieghem T, Vasseur Maurer S, Giannoni E, Baud D. Gastroschisis-what should be told to parents? Prenat Diagn. 2014; 34: 316–26.
  • 4. Chun K, Andrews HG, White JJ. Gastroschisis in successive siblings: further evidence of an acquired etiology. J Pediatr Surg 1993; 28: 838-839
  • 5. Jenkins MM, Reefhuis J, Gallagher ML, Mulle JG, Hoffmann TJ, Koontz DA, et al. Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk. Am J Med Genet. 2014; 164A: 1454– 63.
  • 6. Skarsgard ED. Management of gastroschisis. Curr Opin Pediatr. 2016; 28: 363–9.
  • 7. Raitio A, Lahtinen A, Syvänen J, Kemppainen T, Löyttyniemi E, Gissler M, et al. Gastroschisis in Finland 1993 to 2014-Increasing Prevalence, High Rates of Abortion, and Survival: A Population-Based Study. Eur J Pediatr Surg. 2020; 30(6):536-540.
  • 8. D'Antonio F, Virgone C, Rizzo G, Khalil A, Baud D, Cohen-Overbeek TE, et al. Prenatal risk factors and outcomes in gastroschisis: a meta-analysis. Pediatrics. 2015; 136(1): e159–69.
  • 9. Marshall J, Salemi JL, Tanner JP, Ramakrishnan R, Feldkamp ML, Marengo LK, et al. Prevalence, correlates, and outcomes of Omphalocele in the United States, 1995-2005. Obstet Gynecol. 2015; 126(2): 284–93.
  • 10. Benjamin B, Wilson GN. Registry analysis supports different mechanisms for gastroschisis and omphalocele within shared developmental fields. Am J Med Genet A. 2015; 167A(11): 2568-81.
  • 11. Al-Kaff A, MacDonald SC, Kent N, Burrows J, Skarsgard ED, Hutcheon JA. Delivery planning for pregnancies with gastroschisis: findings from a prospective national registry. Am J Obstet Gynecol. 2015; 213: 557e.1–8.
  • 12. Gamba P, Midrio P. Abdominal wall defects: prenatal diagnosis, newborn management, and long-term outcomes. Semin Pediatr Surg. 2014; 23: 283–90.
  • 13. Bergholz R, Boettcher M, Reinshagen K, Wenke K. Complex gastroschisis is a different entity to simple gastroschisis affecting morbidity and mortality-a systematic review and meta-analysis. J Pediatr Surg. 2014; 49: 1527–32.
  • 14. Lap CC, Brizot ML, Pistorius LR, Kramer WL, Teeuwen IB, Eijkemans MJ, et al. Outcome of isolated gastroschisis; an international study, systematic review and meta-analysis. Early Hum Dev. 2016; 103: 209–18.
  • 15. Corey KM, Hornik CP, Laughon MM, et al. Frequency of anomalies and hospital outcomes in infants with gastroschisis and omphalocele. Early Hum Develop 2014; 90: 421-424.
Toplam 15 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Klinik Tıp Bilimleri
Bölüm Olgu Sunumu
Yazarlar

Mehmet Satar 0000-0002-5718-0503

Ahmet İbrahim Kurtoğlu 0000-0001-8581-5652

Şeref Selçuk Kılıç 0000-0002-3589-3473

Çiğdem Akcabay 0000-0003-2068-7412

Hacer Yapıcıoğlu 0000-0001-6295-553X

Ferda Özlü 0000-0002-2092-8426

Şerif Hamitoğlu

Nejat Narlı 0000-0002-0474-3288

Proje Numarası Yok
Yayımlanma Tarihi 30 Eylül 2021
Kabul Tarihi 19 Mayıs 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 46 Sayı: 3

Kaynak Göster

MLA Satar, Mehmet vd. “Konjenital batın ön Duvarı Defektleri: 4 yıllık Olgu Serisi”. Cukurova Medical Journal, c. 46, sy. 3, 2021, ss. 1309-14, doi:10.17826/cumj.908437.