Relationship of restless legs syndrome with blood parameters

Yıl 2022, Cilt: 47 Sayı: 2, 776 - 782, 30.06.2022

Murat Güntel Alper Uysal Ismet Melek

https://doi.org/10.17826/cumj.1091685

Öz

Purpose: We aimed to investigate the factors affecting the etiopathogenesis by comparing the restless legs syndrome patients with the healthy control group in terms of some laboratory parameters.
Materials and Methods: Patients who were diagnosed with restless legs syndrome were included in the study. A control group that was similar in terms of age and gender was formed. Both groups were compared in terms of iron, ferritin, iron-binding capacity, folate, vitamin B12, vitamin D, calcium, magnesium, ALT, AST, hemogram, creatinine, fasting blood sugar, and thyroid hormone levels.
Results: 37 patients with restless legs syndrome and 41 controls were included in the study. In the restless legs syndrome group hemoglobin, ferritin, iron, fasting blood sugar, vitamin D, and fT4 values were 12.7 (10.3-16.0) g/dL, 37.3 (3.7-89.4) mg/L, 62 (21-195) μg/dL, 96 (65-250) mg/L, 11.26 (4.20-41.57) ug/L and 1.24 (0.73-2.14) µg/dL respectively, they were 14.8 (12.3-16.1) g/dL, 56 (9-189) mg/L, 90 (30-245) µg/dL, 91 (70-107) mg/L, 17.31 (5.73-32.90) µg/L and 1.08 (0.63-2.04) µg/dL respectively in the control group.There were statistically significant differences between the groups in terms of hemoglobin, ferritin, iron, fasting blood sugar, vitamin D, and fT4 levels.
Conclusion: Hemoglobin and iron parameters, vitamin D levels, fasting blood sugar and T4 levels should be evaluated in patients with restless legs syndrome and should be replaced if necessary. Correction of deficiencies may be beneficial for patients' clinics.

Anahtar Kelimeler

Restless Legs Syndrome, Iron Parameters, vitamin D

Huzursuz bacak sendromunun kan parametreleri ile olan ilişkisi

Öz

sağlıklı kontrol grubu ile bazı laboratuvar parametreleri açısından karşılaştırarak etyopatogenezi etkileyen faktörleri araştırmak amaçlanmıştır.
Gereç ve Yöntem: Huzursuz bacak sendromu tanısı konulan hastalar çalışmaya dahil edildi. Yaş ve cinsiyet açısından benzer kontrol grubu oluşturuldu. Her iki grup demir, ferritin, demir bağlama kapasitesi, folat, vitamin B12, vitamin D, kalsiyum, magnezyum, ALT, AST, hemogram, kreatinin, açlık kan şekeri, tiroid hormon seviyeleri açısından karşılaştırıldı.
Bulgular: Çalışmaya 37 huzursuz bacak sendromu hastası, 41 tane de kontrol dahil edildi. Huzursuz bacak sendromu grubunda hemoglobin, ferritin, demir, açlık kan şekeri, D vitamini ve fT4 değerleri sırasıyla 12.7 (10.3-16.0) g/dL, 37.3 (3.7-89.4) mg/L, 62 (21-195) μg/dL, 96 (65-250) mg/L, 11.26 (4.20-41.57) ug/L ve 1.24 (0.73-2.14) µg/dL iken kontrol grubunda sırasıyla 14.8 (12.3-16.1) g/dL, 56 (9-189) mg/L, 90 (30-245) µg/dL, 91 (70-107) mg/L, 17.31 (5.73-32.90) µg/L ve 1.08 (0.63-2.04) µg/dL idi. Hemoglobin, ferritin, demir, açlık kan şekeri, vitamin D ve T4 seviyeleri açısından gruplar arasında istatistiksel olarak anlamlı farklılıklar saptandı.
Sonuç: Huzursuz bacak sendromlu hastalarda hemoglobin ve demir parametreleri, vitamin D düzeyleri, açlık kan şekeri ve T4 seviyeleri eksiklikleri açısından mutlaka değerlendirilmeli, gereklilik halinde mutalaka replase edilmelidir. Eksikliklerin düzeltilmesi hastaların klinikleri açısından yararlı olabilir.

Anahtar Kelimeler

Huzursuz bacak sendromu, Demir parametreleri, d vitamini

Kaynakça

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