Primer hipotiroidizmde vestibüler disfonksiyonun servikal vestibüler uyarılmış miyojenik potansiyeller ile değerlendirilmesi

Yıl 2025, Cilt: 50 Sayı: 3, 579 - 585, 30.09.2025

Ayhan Kars , Fatma Atalay , Kübra Topal , Sezai Sacid Anbar , Fatma Akyel , Korhan Kılıç

https://doi.org/10.17826/cumj.1550967

Öz

Amaç: Bu çalışma, vestibüler semptomları olmayan primer hipotiroidizmli hastalarda servikal vestibüler uyarılmış miyojenik potansiyel (cVEMP) test yanıtlarını değerlendirmek amacıyla yapıldı.
Gereç ve Yöntem: Primer hipotiroidi tanısı konmuş ve henüz hormon replasman tedavisine başlanmamış 31 hasta ile birlikte 26 kişilik bir kontrol grubu araştırmaya dahil edildi. Tüm katılımcılara ayrıntılı kulak burun boğaz muayeneleri, tiroid fonksiyon testleri, cVEMP testleri ve odyolojik testler yapıldı. Gruplar arasında cVEMP kayıtları karşılaştırıldı.
Bulgular: Çalışmaya yaşları 21-57 (38,5±9,7) arasında değişen 31 hasta ve yaşları 20-52 (36,1±8,8) arasında değişen 26 sağlıklı gönüllüden oluşan kontrol grubu dahil edildi. Hasta grubunda 12, kontrol grubunda ise üç kişide VEMP yanıtının olmadığı gözlendi. Hasta grubunda her iki kulaktaki interpeak amplitüdleri (IPAs) kontrol grubuna kıyasla anlamlı olarak düşüktü. Grupların VEMP eşik değerleri arasında anlamlı bir fark bulunmazken, her iki kulaktaki asimetri oranları hasta grubunda anlamlı olarak daha yüksekti.
Sonuç: Servikal vestibüler uyarılmış miyojenik potansiyeller hipotiroidi hastalarında subklinik vestibüler disfonksiyonun tespitinde faydalı olabilir.

Anahtar Kelimeler

Servikal vestibüler uyarılmış miyojenik potansiyeller , hipotiroidizm , tiroid , vertigo , vestibüler sistem.

Etik Beyan

The Kastamonu University Clinical Research Ethical Committee approved this prospective study under decision no. 2020-KAEK-143-29, dated 28.01.2021.

Teşekkür

We want to thank to Mr. Carl Austin Nino Rossini for his precious contribution.

Exploring vestibular dysfunction in primary hypothyroidism using cervical vestibular evoked myogenic potentials

Öz

Purpose: This research was conducted to assess cervical vestibular evoked myogenic potential (cVEMP) test responses in patients with primary hypothyroidism without vestibular symptoms.
Materials and Methods: Thirty-one patients diagnosed with primary hypothyroidism and who had not yet started on hormone replacement therapy, together with a 26-member control group, were enrolled in the research. All participants underwent detailed otorhinolaryngological examinations and thyroid function, cVEMP, and audiological tests. cVEMP records were compared between the groups.
Results: Thirty-one patients aged between 21 and 57 years (38.5±9.7) and a control group of 26 healthy volunteers aged between 20 and 52 years (36.1±8.8) were included in the study. Absent VEMP responses were observed in 12 members of the patient group and in three of the control group. Interpeak amplitudes (IPAs) in both ears were significantly lower in the patient group than in the controls. While no significant difference was found between the groups’ VEMP threshold values, asymmetry rates in both ears were significantly higher in the patient group.
Conclusion: cVEMP can be usefully employed in the detection of subclinical

Anahtar Kelimeler

Cervical vestibular evoked myogenic potentials , vestibular system , hypothyroidism , thyroid , vertigo

Etik Beyan

The Kastamonu University Clinical Research Ethical Committee approved this prospective study under decision no. 2020-KAEK-143-29, dated 28.01.2021.

Teşekkür

We want to thank to Mr. Carl Austin Nino Rossini for his precious contribution.

Kaynakça

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