Araştırma Makalesi
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RADIOMORPHOMETRIC ANALYSIS of PATIENTS of with OSSEOUS DYSPLASIA

Yıl 2025, Cilt: 35 Sayı: 4, 253 - 258, 21.10.2025
https://doi.org/10.17567/currresdentsci.1482986

Öz

Objective:The aim of this study was to examine the radiomorphometric parameters of trabecular and cortical bone of the mandible in patients of osseous dysplasia.
Methods: A total of 43 patients (40 females and 3 males) patients of osseous dysplasia and 43 age and gender-matched healthy individuals (control group) were included in this study. The analyzed radiomorphometric parameters were fractal dimension (FD), mandibular cortical width (MCW), and mandibular cortical index (MCI).
Results:There were not significant differences in the mean FDs of selected regions between the two groups except condyle region (p < 0.005). There were no significant differences in MCW between the two groups (p > 0.05). The mean MCW was 23 mm in the patients of osseous dysplasia and 24 mm in the control group. Therefore there were no significant differences in MCI between the two groups (p > 0.05).
Conclusion: In mandible, especially bone quality of condyle region was significantly lower in patients of osseous dysplasia. Therefore, precaution is needed before surgical interventions in this region. It was also observed that the bone quality of the patients with the three variants of cemental dysplasia in the mandible was similar.

Kaynakça

  • 1. Neville BW, Damm DD, Allen CM, Chi AC. Oral and Maxillofacial Pathology. Elsevier Health Sciences. 2015.
  • 2. White SC, Pharoah M. Oral Radiology: Principles and Interpretation. Elsevier Health Sciences. 2014.
  • 3. Mandelbrot BB. The fractal geometry of nature. W. H. Freeman and Company.1982.
  • 4. El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. WHO Classification of Head and Neck Tumours. 4th edn. Lyon: IARC Press; 2017.
  • 5. Kato CN, Barra SG, Pereira MJ, et al. Mandibular radiomorphometric parameters of women with cemento-osseous dysplasia. Dentomaxillofac Radiol. 2020;49(4):20190359.
  • 6. White SC, Rudolph DJ. Alterations of the trabecular pattern of the jaws in patients with osteoporosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;88:628–635.
  • 7. Klemetti E, Kolmakov S, Kröger H. Pantomography in assessment of the osteoporosis risk group. Scand J Dent Res. 1994;102(1):68–72.
  • 8. Arsan B, Köse TE, Çene E, Özcan İ. Assessment of the trabecular structure of mandibular condyles in patients with temporomandibular disorders using fractal analysis. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017;123:382–391.
  • 9. Munhoz L, Cortes ARG, Arita ES. Assessment of osteoporotic alterations in type 2 diabetes: a retrospective study. Dentomaxillofac Radiol 2017; 46: 20160414.
  • 10. Eser S, Sarıbaş E. Anatomical assessment of the trabecular structure of the alveolar bone in periodontal disease by fractal analysis method. Folia Morphol (Warsz). 2024;83(1):157-167.
  • 11. Korkmaz MZ, Yemenoğlu H, Günaçar DN, Ustaoğlu G, Ateş Yildirim E. The effects of vitamin D deficiency on mandibular bone structure: a retrospective radiological study. Oral Radiol. 2023;39(1):67-74.
  • 12. Balkan EP, Paksoy CS, Bağış N. Fractal analysis of the effects on mandibular bone of botulinum toxin therapy of the masseter muscle in patients with bruxism. Oral Surg Oral Med Oral Pathol Oral Radiol. 2024;137(1):83-88.
  • 13. Yavuz E, Yardimci S. Comparison of periapical radiography, panoramic radiography, and CBCT in the evaluation of trabecular bone structure using fractal analysis. Oral Radiol. 2024;40(3):394–400.
  • 14. Kamburoğlu K. Use of dentomaxillofacial cone beam computed tomography in dentistry. World J Radiol. 2015;7(6):128.
  • 15. de Oliveira CDNA, Barra SG, Abreu LG, et al. Fractal analysis of fibrous dysplasia and ossifying fibroma in 2D and 3D CBCT images. J Oral Maxillofac Surg Med Pathol. 2022;34(6)791-799.
  • 16. Arsan B. Cone beam computed tomography analysis of mandibular inferior cortical thickness and bone texture in cemento-osseous dysplasia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2020;34(1):110-118.
  • 17. Haefliger S, Turek D, Andrei V, et al. Cemento-osseous dysplasia is caused by RAS-MAPK activation. Pathol. 2023;55(3):324-328.
  • 18. Lv M, You G, Wang J, et al. Identification of a novel ANO5 missense mutation in a Chinese family with familial florid osseous dysplasia. J Hum Genet. 2019;64(7):599-607.
  • 19. Klemm P, Aykara I, Lange U. Camurati–Engelmann Disease: A Case-Based Review About an Ultrarare Bone Dysplasia. Eur J Rheumatol. 2023;10(1): 34.
  • 20. Cheng S, Lo IFM, Luk HM. FAM111A-related skeletal dysplasias. In: Adam MP, Feldman J, Mirzaa GM, et al., eds. GeneReviews® [Internet]. Seattle, WA: University of Washington, Seattle; 1993–2025. Updated April 6, 2023.
  • 21. Kato CDNADO, de Arruda JAA, Mendes PA, et al. Infected cemento-osseous dysplasia: analysis of 66 cases and literature review. Head Neck Pathol. 2020;14:173-182.
  • 22. Consolaro A, Paschoal SRB, Ponce JB, Miranda DAO. Florid cemento-osseous dysplasia: a contraindication to orthodontic treatment in compromised areas. Dental Press J Orthod. 2018;23:26-34.
  • 23. Whitt JC, Rokos JW, Dunlap CL, Barker BF. Segmental odontomaxillary dysplasia: report of a series of 5 cases with long-term follow-up. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112(2):29-47.
  • 24. Colak M. An evaluation of bone mineral density using cone beam computed tomography in patients with ectodermal dysplasia: A retrospective study at a single center in Turkey. Med Sci Monit. 2019;25:3503.
  • 25. Leet AI, Chebli C, Kushner H, et al. Fracture incidence in polyostotic fibrous dysplasia and the McCune‐Albright syndrome. J Bone Miner Res. 2004;19(4):571-577.
  • 26. Apolinário AC, Sindeaux R, de Souza Figueiredo PT, et al. (Dental panoramic indices and fractal dimension measurements in osteogenesis imperfecta children under pamidronate treatment. Dentomaxillofac Radiol. 2016;45(4):20150400.

Yıl 2025, Cilt: 35 Sayı: 4, 253 - 258, 21.10.2025
https://doi.org/10.17567/currresdentsci.1482986

Öz

Kaynakça

  • 1. Neville BW, Damm DD, Allen CM, Chi AC. Oral and Maxillofacial Pathology. Elsevier Health Sciences. 2015.
  • 2. White SC, Pharoah M. Oral Radiology: Principles and Interpretation. Elsevier Health Sciences. 2014.
  • 3. Mandelbrot BB. The fractal geometry of nature. W. H. Freeman and Company.1982.
  • 4. El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. WHO Classification of Head and Neck Tumours. 4th edn. Lyon: IARC Press; 2017.
  • 5. Kato CN, Barra SG, Pereira MJ, et al. Mandibular radiomorphometric parameters of women with cemento-osseous dysplasia. Dentomaxillofac Radiol. 2020;49(4):20190359.
  • 6. White SC, Rudolph DJ. Alterations of the trabecular pattern of the jaws in patients with osteoporosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;88:628–635.
  • 7. Klemetti E, Kolmakov S, Kröger H. Pantomography in assessment of the osteoporosis risk group. Scand J Dent Res. 1994;102(1):68–72.
  • 8. Arsan B, Köse TE, Çene E, Özcan İ. Assessment of the trabecular structure of mandibular condyles in patients with temporomandibular disorders using fractal analysis. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017;123:382–391.
  • 9. Munhoz L, Cortes ARG, Arita ES. Assessment of osteoporotic alterations in type 2 diabetes: a retrospective study. Dentomaxillofac Radiol 2017; 46: 20160414.
  • 10. Eser S, Sarıbaş E. Anatomical assessment of the trabecular structure of the alveolar bone in periodontal disease by fractal analysis method. Folia Morphol (Warsz). 2024;83(1):157-167.
  • 11. Korkmaz MZ, Yemenoğlu H, Günaçar DN, Ustaoğlu G, Ateş Yildirim E. The effects of vitamin D deficiency on mandibular bone structure: a retrospective radiological study. Oral Radiol. 2023;39(1):67-74.
  • 12. Balkan EP, Paksoy CS, Bağış N. Fractal analysis of the effects on mandibular bone of botulinum toxin therapy of the masseter muscle in patients with bruxism. Oral Surg Oral Med Oral Pathol Oral Radiol. 2024;137(1):83-88.
  • 13. Yavuz E, Yardimci S. Comparison of periapical radiography, panoramic radiography, and CBCT in the evaluation of trabecular bone structure using fractal analysis. Oral Radiol. 2024;40(3):394–400.
  • 14. Kamburoğlu K. Use of dentomaxillofacial cone beam computed tomography in dentistry. World J Radiol. 2015;7(6):128.
  • 15. de Oliveira CDNA, Barra SG, Abreu LG, et al. Fractal analysis of fibrous dysplasia and ossifying fibroma in 2D and 3D CBCT images. J Oral Maxillofac Surg Med Pathol. 2022;34(6)791-799.
  • 16. Arsan B. Cone beam computed tomography analysis of mandibular inferior cortical thickness and bone texture in cemento-osseous dysplasia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2020;34(1):110-118.
  • 17. Haefliger S, Turek D, Andrei V, et al. Cemento-osseous dysplasia is caused by RAS-MAPK activation. Pathol. 2023;55(3):324-328.
  • 18. Lv M, You G, Wang J, et al. Identification of a novel ANO5 missense mutation in a Chinese family with familial florid osseous dysplasia. J Hum Genet. 2019;64(7):599-607.
  • 19. Klemm P, Aykara I, Lange U. Camurati–Engelmann Disease: A Case-Based Review About an Ultrarare Bone Dysplasia. Eur J Rheumatol. 2023;10(1): 34.
  • 20. Cheng S, Lo IFM, Luk HM. FAM111A-related skeletal dysplasias. In: Adam MP, Feldman J, Mirzaa GM, et al., eds. GeneReviews® [Internet]. Seattle, WA: University of Washington, Seattle; 1993–2025. Updated April 6, 2023.
  • 21. Kato CDNADO, de Arruda JAA, Mendes PA, et al. Infected cemento-osseous dysplasia: analysis of 66 cases and literature review. Head Neck Pathol. 2020;14:173-182.
  • 22. Consolaro A, Paschoal SRB, Ponce JB, Miranda DAO. Florid cemento-osseous dysplasia: a contraindication to orthodontic treatment in compromised areas. Dental Press J Orthod. 2018;23:26-34.
  • 23. Whitt JC, Rokos JW, Dunlap CL, Barker BF. Segmental odontomaxillary dysplasia: report of a series of 5 cases with long-term follow-up. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112(2):29-47.
  • 24. Colak M. An evaluation of bone mineral density using cone beam computed tomography in patients with ectodermal dysplasia: A retrospective study at a single center in Turkey. Med Sci Monit. 2019;25:3503.
  • 25. Leet AI, Chebli C, Kushner H, et al. Fracture incidence in polyostotic fibrous dysplasia and the McCune‐Albright syndrome. J Bone Miner Res. 2004;19(4):571-577.
  • 26. Apolinário AC, Sindeaux R, de Souza Figueiredo PT, et al. (Dental panoramic indices and fractal dimension measurements in osteogenesis imperfecta children under pamidronate treatment. Dentomaxillofac Radiol. 2016;45(4):20150400.
Toplam 26 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Ağız, Diş ve Çene Radyolojisi
Bölüm Araştırma Makalesi
Yazarlar

Sema Kaya 0000-0002-6306-3901

Alaettin Koç 0000-0001-9984-6900

Yayımlanma Tarihi 21 Ekim 2025
Gönderilme Tarihi 13 Mayıs 2024
Kabul Tarihi 30 Temmuz 2024
Yayımlandığı Sayı Yıl 2025 Cilt: 35 Sayı: 4

Kaynak Göster

AMA Kaya S, Koç A. RADIOMORPHOMETRIC ANALYSIS of PATIENTS of with OSSEOUS DYSPLASIA. Curr Res Dent Sci. Ekim 2025;35(4):253-258. doi:10.17567/currresdentsci.1482986

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