Uyku Kalitesinin Kadın Fertilitesi Üzerine Etkileri ve Uyku Kalitesi Değerlendirme Örneği

Öz

Temel yaşam gereksinimlerinden biri olan uyku; kadın sağlığının önemli bir belirleyicisi olarak giderek daha fazla önem kazanmaktadır. Son yıllarda literatürde fertilitenin kadının uyku süresinden ve kalitesinden etkilenip etkilenmediği üzerinde durulmaktadır. Kaliteli uyku fertilite ile ilgili hormonlar da dahil olmak üzere; vücudumuzda görev alan hormonları düzenlemeye ve hasarlı hücrelerin yenilenmesine yardımcı olmaktadır. Fertilite dahil olmak üzere, birçok fizyolojik ve psikolojik olaylar içeren uyku; infertil çiftlerin tedavi sürecinin daha olumlu bir yön bulmasına katkı sağlayabilir. Zorlu tedavi sürecinde iyi bir uyku kalitesine sahip olmak; hem kadına mevcut stresiyle başa çıkması konusunda daha iyi hissettirebilir, hem de kadının sağlıklı oosit üretimine yardımcı olabilir.
Bu derlemenin amacı; uykunun fertiliteyi ne derece ve hangi mekanizmalarda etkileyebildiğini açıklamak, böylece ülkemizde fertilite alanında çalışan hemşireler/sağlık profesyonelleri için bir farkındalık oluşturmaktır. Hemşireler, uykunun fertilite sürecinde önemini anlayarak, infertil çiftlerin değerlendirilmesinde çiftlerin yaşam tarzlarını incelemelerinin önemini kavrayacaklardır. Ayrıca hemşirelerin bu süreçte izleyebilecekleri değerlendirme örneğinin bu alanda çalışan hemşireler/sağlık profesyonelleri için yol gösterici olması amaçlanmıştır..

Anahtar Kelimeler

• uyku
• infertilite
• sirkadiyen ritim
• üreme sağlığı
• kadın sağlığı

The Effects of Sleep Quality on Female Fertility and an Example for the Assessment of Sleep Quality

Öz

Sleep, one of the basic life needs; It is becoming increasingly important as an important determinant of women's health. Recently in the current literature; It is focused on whether fertility is affected by the woman's sleep time and quality. Quality sleep, including hormones related to fertility; It helps regulate the hormones involved in our body and regenerate damaged cells. Sleep involving many physiological and psychological events, including fertility; it can contribute to the infertile couples' finding a more positive direction . Having a good sleep quality during the difficult treatment process; it can both make the woman feel better at dealing with her current stress and help the woman produce healthy oocytes.
The purpose of this review is; explaining to what extent sleep can affect fertility and in which mechanisms, thus creating an awareness for nurses / health professionals working in the field of fertility. By understanding the importance of sleep in the fertility process, nurses will comprehend the importance of examining couples' lifestyle in the evaluation of infertile couples. In addition, it is aimed to guide the nurses / health personnel working in the field by creating an evaluation example that they can follow in this evaluation.

Anahtar Kelimeler

• Sleep
• Infertility
• Circadian Rhythm
• Reproductive Health
• Women's Health

Kaynakça

1. 1. Speroff L, Fritz M. The gynecologic endocrinology and infertility. 7th Edition. Lippincott Williams & Wilkins. Philadelphia. 2005. p. 187-224.
2. 2. Amanak K, Karagöz B, Sevil Ü. Effect of the modern life on infertility. TAF Prev Med Bull. 2014; 13(4): 345-350.
3. 3. Sharma R, Biedenharn K, Fedor F, Agarwa A. Lifestyle factors and reproductive health: taking control of your fertility. Reproductive Biology and Endocrinology. 2013; 1477-7827.
4. 4. Piche M, Babineau V, Robitaille J, Lachance E, Ruchat S. Lifestyle-related factors associated with reproductive health in couples seeking fertility treatments: results of pilot study. International Journal of Fertility and Sterility. 2018; 12(1): 19-26
5. 5. Lin J, Lin Y, Chuch K. Somatic symptoms, psychological distress and sleep disturbance among infertile women with intrauterine insemination treatment. Journal of Clinical Nursing. 2014; Jun;23(11-12):1677-84.
6. 6. Lin J, Lin Y, Chuch K. Somatic symptoms, psychological distress and sleep disturbance among women undergoing oocyte pick-up and in vitro fertilization-embryo transfer. Journal of Clinical Nursing. 2016; Jun;25(11-12):1748-56.
7. 7. Goldstein C, Lanham M, Smith Y, O’Brien L. Sleep in women undergoing in vitro fertilization: a pilot study. Sleep Medicine Journal. 2017; 105-113.
8. 8. Tamura H, Nakamura Y, Takiguchi S, et al. Melatonin directly suppresses steroid production by preovulatory follicles in the cyclic hamster, J Pineal Res. 1998; 25: 135–41.

9. 9. Hirshowitz M, Whiton K, Albert SM, Alessi C, Bruni O, DonCarlos L, et al. National sleep foundation’s updated sleep duration recommendations: final report. Sleep Health. 2015; 1(4):233-43.
10. 10. Guyton AC, Hall JE. Medical Physiology. 13th edition. USA, 2016. p.689-690.
11. 11. Zee PC, Mantena P. The brain’s master circadian clock; implications and opportunities for theraphy of sleep disorders, Sleep Med Rev. 2007; 11:59-70.
12. 12. Gooley JJ, Saper CB. Anatomy of the mammalian circadian system. In Principles and Practice of Sleep Medicine. (Eds MH Kryger, T Roth, WC Dement): 2005; 335-350. Philadelphia: Elsevier Saunders.
13. 13. Agarwal A. Oxidative stress and its implications in female infertility – a clinician’s perspective. Reproductive Bio Medicine. 2005;11:641-50.
14. 14. Tamura H, Takasak A, Taketani T, Tanabe M, Kizuka F, Lee L et al. The role melatonin as an antioxidant in the follicle. Journal of Ovarian Research. 2012;5:5
15. 15. M. Figueiro, D. Overington. Self-luminous devices and melatonin suppression in adolescents. Lighting Research& Technology. Lighting Res. Technol. 2015; 0: 1–10.
16. 16. Rad S, Abbasalizadeh S, Haghjo A, Sadagheyani M, Montaseri A, Rad J. Evaluation of the melatonin and oxidative stress markers level in serum of fertile women. Iran Reproductiv Medicine. 2015; 439-444.
17. 17. Akamatsu S, Otsuki J, Fujii M, Enatsu N, Tsuji Y, Iwasaki T et al. The poor quality of women’s sleep negatively influences fertilization rates in assisted reproductive technoogy. International Journal of Fertility and Sterility. 2016; 108(3):e120.
18. 18. Park I, Sun H, Jeon G, Jo J, Kim S, Lee K. The more, the better? the impact of sleep on IVF outcomes. International Journal of Fertility and Sterility. 2013.
19. 19. Eryılmaz Ö, Devran A, Sarikaya E, Aksakal F, Mollamahmutoğlu L, Cicek N. Melatonin improves the oocyte and embriyo in IVF patients with sleep disturbances, but does not improve the sleeping problems. Assisted Reproduction Technologies. 2011; 28:815-820.