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Effect of Complementary and Supportive Applications on Symptoms and Functional Status in Women with Knee Osteoarthritis

Yıl 2021, Cilt: 14 Sayı: 2, 94 - 101, 15.04.2021
https://doi.org/10.46483/deuhfed.714475

Öz

Background: In the majority of patients with osteoarthritis (OA), it is seen that the symptoms associated with the disease are not effectively managed. Objective: This study aimed to determine the use of complementary and supportive applications (CSA) and the symptoms and functional status of the methods used in women with knee osteoarthritis. Methods: This descriptive study consisted of 255 women with knee OA who applied to the rheumatology outpatient clinic of a state and a university hospital between May and December 2017. Data were collected using the questionnaire prepared by the author on the basis of a literature review and Knee Injury and Osteoarthritis Outcome Score. Descriptive statistics, Mann–Whitney U test, and Kruskal–Wallis H test were used to evaluate the data. Results: Results showed that 22% of women with OA of the knee used CSA and 75% of these women used herbal treatment; 55.4% used these therapies on the advice of people around them, and 83.9% did not inform the health personnel about the method they used. Half the women stated that they had benefited from the method they used. The mean scores of pain and daily life activities were found to be significantly higher (p < 0.05) in women using alternative therapies compared with those not using them. The difference between the mean scores of the KOOS sub-dimension of patients using complementary and supportive care according to age, education level and year of illness was found to be statistically significant (p < 0.005). Conclusion: It was determined that women with knee OA used complementary and supportive care methods because of the pain and benefited from these methods. It was found that the pain and daily living activity scores of the patients using these methods were higher than those who did not.

Kaynakça

  • 1. Andriacchi TP, Griffin TM, Loeser RF, Chu CR, Roos EM, Hawker GA, et al. Bridging disciplines as a pathway to finding new solutions for osteoarthritis a collaborative program presented at the 2019 orthopedic research society and the osteoarthritis research society international. Osteoarthr Cartil 2020:2(1);1-7.
  • 2. Kooshki A, Forouzan R, Rakhshani MH, Mohammadi M. Effect of topical application of nigella sativa oil and oral acetaminophen on pain in elderly with knee osteoarthritis: A crossover clinical trial. Electron Physician 2016;8(11):3193-3197.
  • 3. World Health Organization. Chronic rheumatic conditions [online]. 2020. URL: http://www.who.int/chp/topics/rheumatic/en/#.WXC3gRWCqIU.link. 05 Nisan 2021
  • 4. Kellgren J, Moore R. Generalized osteoarthritis and heberden's nodes. Br Med J 1952;1(4751):181.
  • 5. Jin X, Wang BH, Wang X, Antony B, Zhu Z, Han W, et al. Associations between endogenous sex hormones and MRI structural changes in patients with symptomatic knee osteoarthritis. Osteoarthr Cartil 2017;25(7):1100-1106.
  • 6. Khalid AB, Krum SA. Estrogen receptors alpha and beta in bone. Bone 2016;87:130-135.
  • 7. Abbas H, Mirza N. Cytokine and hormonal profile in osteoarthritis subjects. J Med Sci 2019;27(1):38-41.
  • 8. Driban JB, Bannuru RR, Eaton CB, Spector TD, Hart DJ, McAlindon TE, et al. The incidence and characteristics of accelerated knee osteoarthritis among women: the Chingford cohort. BMC Musculoskelet Disord 2020;21(1):60-66.
  • 9. Mahajan A, Patni R. Menopause and osteoarthritis: Any association? J Mid-life Health 2018;9(4):171-172.
  • 10. Kim C, Stebbings S, Sundberg T, Munk N, Lauche R, Ward L. Complementary medicine for the management of knee and hip osteoarthritis–A patient perspective. Musculoskeletal Care 2020;18(1):53-63.
  • 11. Şaş S, Büyükturan Ö, Büyükturan B. Kas iskelet sistemi hastalıklarında tamamlayıcı ve alternatif tıp yöntemleri kullanım sıklığının değerlendirilmesi. Sakarya Tıp Dergisi 2018;8(3):481-488.
  • 12. Teymouri S, Rakhshandeh H, Baghdar HN, Yousefi M, Salari R. Analgesic herbal medicines in the treatment of knee osteoarthritis: A systematic review. Curr Rheumatol Rev 2019;15(4):290-303.
  • 13. NCCIH. Important events in NCCIH history: U.S. Department of Health & Human Services, National Institutes of Health [online]. 2020. URL: https://www.nih.gov/about-nih/what-we-do/nih-almanac/national-center-complementary-integrative-health-nccih. 05 Nisan 2021
  • 14. TC. Sağlık Bakanlığı. Geleneksel ve tamamlayıcı tıp daire başkanlığı uygulama merkezleri [online]. 2020. URL: https://getatportal.saglik.gov.tr/TR,8501/rehberler.html. 05 Nisan 2021
  • 15. Balouchi A, Mahmoudirad G, Hastings-Tolsma M, Shorofi SA, Shahdadi H, Abdollahimohammad A. Knowledge, attitude and use of complementary and alternative medicine among nurses: A systematic review. Complement Ther Clin Pract 2018;31:146-157.
  • 16. Shorofi SA, Arbon P. Complementary and alternative medicine (CAM) among Australian hospital-based nurses: Knowledge, attitude, personal and professional use, reasons for use, CAM referrals, and socio-demographic predictors of CAM users. Complement Ther Clin Pract 2017;27:37-45.
  • 17. Hall H, Brosnan C, Frawley J, Wardle J, Collins M, Leach M. Nurses’ communication regarding patients’ use of complementary and alternative medicine. Collegian 2018;25(3):285-291.
  • 18. Kılıç KN, Soylar P. Geleneksel ve tamamlayıcı tıp uygulamalarına başvuran bireylerin tutumları, başvurma nedenleri ve memnuniyet düzeylerinin incelenmesi. J Tradit Complem Med 2019;2(3):97-105.
  • 19. Ayaz S, Rathore F, Rathore F, Rathore F, Ahmad K, Gill Z. The use of complementary and alternative medicine therapies among patients with knee osteoarthritis in pakistan: A hospital based survey. Int J Rehabil Sci 2018;32(2):111-116.
  • 20. Dikici A, Ulaşlı AM, Çevik H, Eroğlu S, Solak Ö, Dündar Ü. Dejeneratif osteoartrit tanılı hastalarda tamamlayıcı ve alternatif tıp kullanımı. Eurasian Journal of Family Medicine 2015;4(3):126-30.
  • 21. Yang L, Sibbritt D, Adams J. A critical review of complementary and alternative medicine use among people with arthritis: A focus upon prevalence, cost, user profiles, motivation, decision-making, perceived benefits and communication. Rheumatol Int 2017;37(3):337-351.
  • 22. Roos EM, Juhl CB. Osteoarthritis 2012 year in review: Rehabilitation and outcomes. Osteoarthr Cartil 2012;20(12):1477-1483.
  • 23. Paker N, Bugdaycı D, Sabırlı F, Özel S, Ersoy S. Knee injury and osteoarthritis outcome score: Reliability and validation of the Turkish version. Turkiye Klinikleri J Med Sci. 2007;27:350-356.
  • 24. Phang JK, Kwan YH, Goh H, Tan VIC, Thumboo J, Østbye T and Fong W. Complementary and alternative medicine for rheumatic diseases: a systematic review of randomized controlled trials. Complement Ther Med 2018;37:143-157.
  • 25. Tharakan CS, Ungcharoen N, Sabu J, Moorthy A. THU0650 complementary and alternative medicine in rheumatology: A survey of its use for common rheumatological conditions among multi-ethnic patients in leicestershire. Ann Rheum Dis 2019;78:621.
  • 26. Shafii NAHN, Yaacob LH, Ishak A, Kadir AA. Traditional and complementary medicine use in knee osteoarthritis and its associated factors among patients in northeast peninsular malaysia. Oman Med J 2018;33(2):148.
  • 27. Bruyère O, Cooper C, Pelletier J-P. An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: A report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Semin Arthritis Rheum 2014;44(3):253-263.
  • 28. Bannuru RR, Osani M, Vaysbrot E, Arden N, Bennell K, Bierma-Zeinstra S, et al. OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis. Osteoarthr Cartil 2019;27(11):1578-1589.
  • 29. Cantista P, Maraver F. Balneotherapy for knee osteoarthritis in S. Jorge: A randomized controlled trial. Int J Biometeorology 2020;64(6):1027-1038.
  • 30. Antonelli M, Donelli D, Fioravanti A. Effects of balneotherapy and spa therapy on quality of life of patients with knee osteoarthritis: A systematic review and meta-analysis. Rheumatology Int 2018;38(10):1807-1824.
  • 31. Dilekçi E, Özkuk K, Kaki B. Effect of balneotherapy on pain and fatigue in elderly with knee osteoarthritis receiving physical therapy: A randomized trial. Int J Biometeorology 2019;63(12):1555-1568.
  • 32. Kısa İ, Ok E, Er F. Osteoartrit Tanılı Hastalarda Balneoterapinin Ağrı, Depresyon Belirtileri, Uyku ve Yaşam Kalitesi Üzerine Etkisi. J Tradit Complem Med. 2020;3(1):27-33.
  • 33. Durmuş İskender M, Eren H. Türkiye’de Ağrıya Yönelik Akupresur Uygulaması ile İlgili Yapılmış Hemşirelik Tezlerinin İncelenmesi. J Tradit Complem Med. 2020;3(1):40-46.
  • 34. Yang L, Sibbritt D, Adams J. A critical review of complementary and alternative medicine use among people with arthritis: A focus upon prevalence, cost, user profiles, motivation, decision-making, perceived benefits and communication. Rheumatol Int 2017;37(3):337-351.
  • 35. Bai FY, Xu QL. Difference between China and Europe acupuncture in the treatment of degenerative knee arthritis. In AIP Conference Proceedings 2020; 2252(1):020019.
  • 36. Karadağ A, Hayta E, Kaptanoğlu E, Konak A. Complementary and alternative treatment methods in chronic rheumatic diseases in the Central Anatolia. Electron J Gen Med 2018;15(4):1-7.
  • 37. Pandey P, Tiwari S. Therapeutic potential of Indian plants for the treatment of rheumatoid arthritis. Journal of Pharmacognosy and Phytochemistry 2018;7(3):37-41.
  • 38. Khan MU, Jamshed SQ, Ahmad A, Bidin MABA, Siddiqui MJ, Al-Shami AK. Use of complementary and alternative medicine among osteoarthritic patients: A review. J Clin Diagn Res 2016;10(2):1-6.
  • 39. Nasiri A, Mahmodi MA. Aromatherapy massage with lavender essential oil and the prevention of disability in ADL in patients with osteoarthritis of the knee: A randomized controlled clinical trial. Complement Ther Clin Pract 2018;30:116-121.
  • 40. Branco M, Rêgo NN, Silva PH, Archanjo IE, Ribeiro MC, Trevisani VF. Bath thermal waters in the treatment of knee osteoarthritis: A randomized controlled clinical trial. Eur J Phys Rehabil Med 2016;52(4):422-430.
  • 41. Field T. Knee osteoarthritis pain in the elderly can be reduced by massage therapy, yoga and tai chi: A review. Complement Ther Clin Pract 2016;22:87-92.
  • 42. Shoara R, Hashempur MH, Ashraf A, Salehi A, Dehshahri S, Habibagahi Z. Efficacy and safety of topical matricaria chamomilla l. (chamomile) oil for knee osteoarthritis: A randomized controlled clinical trial. Complement Ther Clin Pract 2015;21(3):181-187.
  • 43. Ng JY, Azizudin AM. Rheumatoid arthritis and osteoarthritis clinical practice guidelines provide few complementary and alternative medicine therapy recommendations: A systematic review. Clin Rheumatol 2020;39:2861-2873.

Diz Osteoartritli Kadınlarda Tamamlayıcı ve Destekleyici Uygulamanın Semptom ve Fonksiyonel Duruma Etkisi

Yıl 2021, Cilt: 14 Sayı: 2, 94 - 101, 15.04.2021
https://doi.org/10.46483/deuhfed.714475

Öz

Giriş: Osteoartritli (OA) hastaların çoğunda, hastalıkla ilişkili semptomların etkili bir şekilde yönetilmediği görülmektedir. Amaç: Araştırma, diz OA’li kadınların tamamlayıcı ve destekleyici uygulama (TDU) kullanım durumları ile kullanılan yöntemlerin semptom ve fonksiyonel durumunu belirlemek amacıyla yapılmıştır. Yöntem: Tanımlayıcı çalışmanın örneklemini, bir devlet ve bir üniversite hastanesinin romatoloji polikliniğinde Mayıs -Aralık 2017 tarihleri arasında başvuran 255 kadın hasta oluşturmuştur. Çalışmanın verileri, Tanıtıcı Bilgiler Formu ve Diz İncinme ve Osteoartrit Sonuç Skoru Ölçeği (KOOS) kullanılarak toplanmıştır. Verilerin değerlendirilmesinde, tanımlayıcı ista
tistikler, Mann-Whitney U testi, Kruskal-Wallis H testi kullanılmıştır. Bulgular: Çalışmada, OA’li kadınların %22’sinin TDU ve bunun %75’ini bitkisel desteğin oluşturduğu, hastaların %55.4’ünün sosyal çevre tavsiyesi ile TDU’ya başvurduğu, %83.9’unun ise kullandığı yönteme ilişkin sağlık personeline bilgi vermediği belirlenmiştir. Hastaların yarısı kullandıkları yöntemden fayda gördüklerini ifade etmişlerdir. Hastaların tamamı ağrı şikayetleri nedeniyle TDU yöntemlerini kullandıklarını ifade etmiştir. TDU kullanan hastaların ağrı ve günlük yaşam aktiviteleri puan ortalamalarının, kullanmayan hastalara göre istatistiksel olarak anlamlı düzeyde daha yüksek olduğu tespit edilmiştir (p < 0.05). TDU kullanan hastaların yaş, eğitim durumu ve hastalık yılına göre KOOS alt boyut puan ortalamaları arasındaki fark istatistiksel olarak anlamlı bulunmuştur (p < 0.005). Sonuç: Diz OA’lı kadınların ağrı nedeniyle TDU yöntemlerini kullandıkları ve bu yöntemlerden fayda gördükleri belirlenmiştir. Bu yöntemleri kullanan hastaların ağrı ve günlük yaşam aktivite puanlarının kullanmayanlara göre daha yüksek olduğu saptanmıştır.

Kaynakça

  • 1. Andriacchi TP, Griffin TM, Loeser RF, Chu CR, Roos EM, Hawker GA, et al. Bridging disciplines as a pathway to finding new solutions for osteoarthritis a collaborative program presented at the 2019 orthopedic research society and the osteoarthritis research society international. Osteoarthr Cartil 2020:2(1);1-7.
  • 2. Kooshki A, Forouzan R, Rakhshani MH, Mohammadi M. Effect of topical application of nigella sativa oil and oral acetaminophen on pain in elderly with knee osteoarthritis: A crossover clinical trial. Electron Physician 2016;8(11):3193-3197.
  • 3. World Health Organization. Chronic rheumatic conditions [online]. 2020. URL: http://www.who.int/chp/topics/rheumatic/en/#.WXC3gRWCqIU.link. 05 Nisan 2021
  • 4. Kellgren J, Moore R. Generalized osteoarthritis and heberden's nodes. Br Med J 1952;1(4751):181.
  • 5. Jin X, Wang BH, Wang X, Antony B, Zhu Z, Han W, et al. Associations between endogenous sex hormones and MRI structural changes in patients with symptomatic knee osteoarthritis. Osteoarthr Cartil 2017;25(7):1100-1106.
  • 6. Khalid AB, Krum SA. Estrogen receptors alpha and beta in bone. Bone 2016;87:130-135.
  • 7. Abbas H, Mirza N. Cytokine and hormonal profile in osteoarthritis subjects. J Med Sci 2019;27(1):38-41.
  • 8. Driban JB, Bannuru RR, Eaton CB, Spector TD, Hart DJ, McAlindon TE, et al. The incidence and characteristics of accelerated knee osteoarthritis among women: the Chingford cohort. BMC Musculoskelet Disord 2020;21(1):60-66.
  • 9. Mahajan A, Patni R. Menopause and osteoarthritis: Any association? J Mid-life Health 2018;9(4):171-172.
  • 10. Kim C, Stebbings S, Sundberg T, Munk N, Lauche R, Ward L. Complementary medicine for the management of knee and hip osteoarthritis–A patient perspective. Musculoskeletal Care 2020;18(1):53-63.
  • 11. Şaş S, Büyükturan Ö, Büyükturan B. Kas iskelet sistemi hastalıklarında tamamlayıcı ve alternatif tıp yöntemleri kullanım sıklığının değerlendirilmesi. Sakarya Tıp Dergisi 2018;8(3):481-488.
  • 12. Teymouri S, Rakhshandeh H, Baghdar HN, Yousefi M, Salari R. Analgesic herbal medicines in the treatment of knee osteoarthritis: A systematic review. Curr Rheumatol Rev 2019;15(4):290-303.
  • 13. NCCIH. Important events in NCCIH history: U.S. Department of Health & Human Services, National Institutes of Health [online]. 2020. URL: https://www.nih.gov/about-nih/what-we-do/nih-almanac/national-center-complementary-integrative-health-nccih. 05 Nisan 2021
  • 14. TC. Sağlık Bakanlığı. Geleneksel ve tamamlayıcı tıp daire başkanlığı uygulama merkezleri [online]. 2020. URL: https://getatportal.saglik.gov.tr/TR,8501/rehberler.html. 05 Nisan 2021
  • 15. Balouchi A, Mahmoudirad G, Hastings-Tolsma M, Shorofi SA, Shahdadi H, Abdollahimohammad A. Knowledge, attitude and use of complementary and alternative medicine among nurses: A systematic review. Complement Ther Clin Pract 2018;31:146-157.
  • 16. Shorofi SA, Arbon P. Complementary and alternative medicine (CAM) among Australian hospital-based nurses: Knowledge, attitude, personal and professional use, reasons for use, CAM referrals, and socio-demographic predictors of CAM users. Complement Ther Clin Pract 2017;27:37-45.
  • 17. Hall H, Brosnan C, Frawley J, Wardle J, Collins M, Leach M. Nurses’ communication regarding patients’ use of complementary and alternative medicine. Collegian 2018;25(3):285-291.
  • 18. Kılıç KN, Soylar P. Geleneksel ve tamamlayıcı tıp uygulamalarına başvuran bireylerin tutumları, başvurma nedenleri ve memnuniyet düzeylerinin incelenmesi. J Tradit Complem Med 2019;2(3):97-105.
  • 19. Ayaz S, Rathore F, Rathore F, Rathore F, Ahmad K, Gill Z. The use of complementary and alternative medicine therapies among patients with knee osteoarthritis in pakistan: A hospital based survey. Int J Rehabil Sci 2018;32(2):111-116.
  • 20. Dikici A, Ulaşlı AM, Çevik H, Eroğlu S, Solak Ö, Dündar Ü. Dejeneratif osteoartrit tanılı hastalarda tamamlayıcı ve alternatif tıp kullanımı. Eurasian Journal of Family Medicine 2015;4(3):126-30.
  • 21. Yang L, Sibbritt D, Adams J. A critical review of complementary and alternative medicine use among people with arthritis: A focus upon prevalence, cost, user profiles, motivation, decision-making, perceived benefits and communication. Rheumatol Int 2017;37(3):337-351.
  • 22. Roos EM, Juhl CB. Osteoarthritis 2012 year in review: Rehabilitation and outcomes. Osteoarthr Cartil 2012;20(12):1477-1483.
  • 23. Paker N, Bugdaycı D, Sabırlı F, Özel S, Ersoy S. Knee injury and osteoarthritis outcome score: Reliability and validation of the Turkish version. Turkiye Klinikleri J Med Sci. 2007;27:350-356.
  • 24. Phang JK, Kwan YH, Goh H, Tan VIC, Thumboo J, Østbye T and Fong W. Complementary and alternative medicine for rheumatic diseases: a systematic review of randomized controlled trials. Complement Ther Med 2018;37:143-157.
  • 25. Tharakan CS, Ungcharoen N, Sabu J, Moorthy A. THU0650 complementary and alternative medicine in rheumatology: A survey of its use for common rheumatological conditions among multi-ethnic patients in leicestershire. Ann Rheum Dis 2019;78:621.
  • 26. Shafii NAHN, Yaacob LH, Ishak A, Kadir AA. Traditional and complementary medicine use in knee osteoarthritis and its associated factors among patients in northeast peninsular malaysia. Oman Med J 2018;33(2):148.
  • 27. Bruyère O, Cooper C, Pelletier J-P. An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: A report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Semin Arthritis Rheum 2014;44(3):253-263.
  • 28. Bannuru RR, Osani M, Vaysbrot E, Arden N, Bennell K, Bierma-Zeinstra S, et al. OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis. Osteoarthr Cartil 2019;27(11):1578-1589.
  • 29. Cantista P, Maraver F. Balneotherapy for knee osteoarthritis in S. Jorge: A randomized controlled trial. Int J Biometeorology 2020;64(6):1027-1038.
  • 30. Antonelli M, Donelli D, Fioravanti A. Effects of balneotherapy and spa therapy on quality of life of patients with knee osteoarthritis: A systematic review and meta-analysis. Rheumatology Int 2018;38(10):1807-1824.
  • 31. Dilekçi E, Özkuk K, Kaki B. Effect of balneotherapy on pain and fatigue in elderly with knee osteoarthritis receiving physical therapy: A randomized trial. Int J Biometeorology 2019;63(12):1555-1568.
  • 32. Kısa İ, Ok E, Er F. Osteoartrit Tanılı Hastalarda Balneoterapinin Ağrı, Depresyon Belirtileri, Uyku ve Yaşam Kalitesi Üzerine Etkisi. J Tradit Complem Med. 2020;3(1):27-33.
  • 33. Durmuş İskender M, Eren H. Türkiye’de Ağrıya Yönelik Akupresur Uygulaması ile İlgili Yapılmış Hemşirelik Tezlerinin İncelenmesi. J Tradit Complem Med. 2020;3(1):40-46.
  • 34. Yang L, Sibbritt D, Adams J. A critical review of complementary and alternative medicine use among people with arthritis: A focus upon prevalence, cost, user profiles, motivation, decision-making, perceived benefits and communication. Rheumatol Int 2017;37(3):337-351.
  • 35. Bai FY, Xu QL. Difference between China and Europe acupuncture in the treatment of degenerative knee arthritis. In AIP Conference Proceedings 2020; 2252(1):020019.
  • 36. Karadağ A, Hayta E, Kaptanoğlu E, Konak A. Complementary and alternative treatment methods in chronic rheumatic diseases in the Central Anatolia. Electron J Gen Med 2018;15(4):1-7.
  • 37. Pandey P, Tiwari S. Therapeutic potential of Indian plants for the treatment of rheumatoid arthritis. Journal of Pharmacognosy and Phytochemistry 2018;7(3):37-41.
  • 38. Khan MU, Jamshed SQ, Ahmad A, Bidin MABA, Siddiqui MJ, Al-Shami AK. Use of complementary and alternative medicine among osteoarthritic patients: A review. J Clin Diagn Res 2016;10(2):1-6.
  • 39. Nasiri A, Mahmodi MA. Aromatherapy massage with lavender essential oil and the prevention of disability in ADL in patients with osteoarthritis of the knee: A randomized controlled clinical trial. Complement Ther Clin Pract 2018;30:116-121.
  • 40. Branco M, Rêgo NN, Silva PH, Archanjo IE, Ribeiro MC, Trevisani VF. Bath thermal waters in the treatment of knee osteoarthritis: A randomized controlled clinical trial. Eur J Phys Rehabil Med 2016;52(4):422-430.
  • 41. Field T. Knee osteoarthritis pain in the elderly can be reduced by massage therapy, yoga and tai chi: A review. Complement Ther Clin Pract 2016;22:87-92.
  • 42. Shoara R, Hashempur MH, Ashraf A, Salehi A, Dehshahri S, Habibagahi Z. Efficacy and safety of topical matricaria chamomilla l. (chamomile) oil for knee osteoarthritis: A randomized controlled clinical trial. Complement Ther Clin Pract 2015;21(3):181-187.
  • 43. Ng JY, Azizudin AM. Rheumatoid arthritis and osteoarthritis clinical practice guidelines provide few complementary and alternative medicine therapy recommendations: A systematic review. Clin Rheumatol 2020;39:2861-2873.
Toplam 43 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Hemşirelik
Bölüm Araştırma Makaleleri
Yazarlar

Afra Çalık 0000-0001-7277-3393

Sevgisun Kapucu 0000-0003-3908-3846

Yayımlanma Tarihi 15 Nisan 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 14 Sayı: 2

Kaynak Göster

APA Çalık, A., & Kapucu, S. (2021). Diz Osteoartritli Kadınlarda Tamamlayıcı ve Destekleyici Uygulamanın Semptom ve Fonksiyonel Duruma Etkisi. Dokuz Eylül Üniversitesi Hemşirelik Fakültesi Elektronik Dergisi, 14(2), 94-101. https://doi.org/10.46483/deuhfed.714475

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