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3 Aydan küçük İnfantlarda yapılan Piyeloplasti sonuçlarımız

Yıl 2025, Cilt: 52 Sayı: 4, 883 - 890, 12.12.2025
https://doi.org/10.5798/dicletip.1841273

Öz

Amaç: Üreteropelvik bileşke obstrüksiyonu (UPBO), genellikle antenatal dönemde tanı alan ve yaklaşık %0,1 insidansla görülen konjenital bir anomalidir. Açık dismembered pyeloplasti yüksek başarı oranları nedeniyle günümüzde altın standart yöntem olarak kabul edilmektedir. Bu çalışmada üç aydan küçük infantlarda uygulanan ‘minyatürize ekstrakorporeal dismembered pyeloplasti (MExDP) tekniğinin fonksiyonel ve postoperatif sonuçları değerlendirilmiştir.
Yöntemler: Kasım 2019 - Nisan 2025 tarihleri arasında antenatal hidronefroz tanısı ile merkezimize yönlendirilen ve UPBO tanısı konularak cerrahi endikasyonu olan 58 infant retrospektif olarak incelendi. Preoperatif değerlendirmede ultrasonografi, laboratuvar analizleri ve diüretikli MAG3 sintigrafi uygulandı. Cerrahi endikasyon kriterleri arasında split renal fonksiyon <%40, parankim kalınlığı <3 mm, progresif AP çap >40 mm ve SFU evre 3-4 hidronefroz yer aldı. Tüm olgular tek cerrah tarafından 2 cm subkostal mini insizyonla opere edildi. İntraoperatif ve postoperatif bulgular kayıt altına alındı.
Bulgular: Olguların yaş ortalaması 65,3 gündü (32–88). Ortalama insizyon uzunluğu 2,1 cm, ortalama operasyon süresi 65 dakika olarak belirlendi. Peroperatif olarak bir olguda retrokaval üreter, iki olguda aberran damar ve 55 olguda primer UPBO saptandı. Komplikasyon oranı %3 olup majör komplikasyon gözlenmedi. Postoperatif 3. ayda tüm olgularda hidronefroz derecesinde gerileme ve MAG3 sintigrafide drenajda düzelme izlendi. Başarı oranı %100 idi.
Sonuç: MExDP tekniği, üç aydan küçük infantlarda UPBO tedavisinde güvenilir ve etkili bir yöntemdir. Daha küçük cerrahi kesi, daha az postoperatif ağrı, daha hızlı iyileşme ve üstün kozmetik sonuçlar sağlamasıyla öne çıkmaktadır. Robotik veya laparoskopik cerrahi imkanı bulunmayan merkezlerde MExDP, pratik ve uygulanabilir bir alternatif olarak değerlendirilebilir.

Etik Beyan

Çalışma için Etik Kurul onay alındı (308/2025).

Kaynakça

  • 1.Nguyen HT, Herndon CD, Cooper C, et al. TheSociety for Fetal Urology consensus statement onthe evaluation and management of antenatalhydronephrosis. J Pediatr Urol. 2010; 6: 212-31.
  • 2.Yarmohamadi A, Saeedi P, Hoghabrosadat A.Surgical Results of Anderson-Hynes DismemberedPyeloplasty Without Internal Drainage in AdultsWith Ureteroplevic Junction Obstruction. NephroUrol Mon. 2015 May; 7: e21800.
  • 3.Piaggio LA, Corbetta JP, Weller S, et al.Comparative, prospective, case–control study ofopen versus laparoscopic pyeloplasty in childrenwith ureteropelvic junction obstruction: long-termresults. Front Pediatr. 2017; 5: 10-7.
  • 4.El-Abd SA, Bastawisy MG, Ramadan AR, El-Abd AS.Pyeloplasty the dilemma: open, endoscopic, orlaparoscopic? Clin Surg. 2018; 3: 2031.
  • 5.Sharma L, Ahmed N, Bhat M, et al. Laparoscopicpyeloplasty: our experience of initial fifty two cases.J Urol Surg. 2020; 7: 125-9.
  • 6.Tufekci EC, Karabulut A, Gokce MI, et al. Mini openpyeloplasty in infants: an alternative with goodcosmetic outcomes. J Pediatr Surg. 2020; 55: 695-9.
  • 7.Hodhod A, Eid H, Fermin-Risso C, et al. Significantimprovement in hydronephrosis with pyeloplastyprior to 3 months of age in patients with antenatalsevere hydronephrosis. Int Urol Nephrol. 2024; 56:2467-73.
  • 8.Elbaset MA, Zahran MH, Sharaf MA, et al. Longterm functional success after pyeloplasty for pelvi-ureteral junction obstruction in unilateral poorlyfunctioning kidney in exclusively adults population.Urology. 2019; 131:234-9.
  • 9.Vidhya T, Rajiv P, Sripathi V. Analysis of outcomesof robot-assisted laparoscopic pyeloplasty inchildren from a tertiary pediatric center in SouthIndia. Front Pediatr. 2021; 9: 642923.
  • 10.Gadelmoula M, Abdel-Kader MS, Shalaby M, et al.Laparoscopic versus open pyeloplasty: a multi-institutional prospective study. Cent European JUrol. 2018; 71: 342-5.
  • 11.Esposito C, Cerulo M, Lepore B, et al. Robotic-assisted pyeloplasty in children: a systematic reviewof the literature. J Robot Surg. 2023; 17:1239-46.
  • 12.Sharma L, Ahmed N, Bhat M, et al. Laparoscopicpyeloplasty: our experience of initial fifty two cases.J Urol Surg. 2020; 7: 125-9.
  • 13.Cui X, Li H, Sun N, Wei X, Li Z. Mini-laparoscopicpyeloplasty versus open pyeloplasty forureteropelvic junction obstruction in infants: acomparative study. Minim Invasive Ther AlliedTechnol. 2022; 31: 473-8.
  • 14.Langreen S, Ludwikowski B, Dingemann J, et al.Laparoscopic pyeloplasty in neonates and infants issafe and efficient. Front Pediatr. 2024; 12: 1397614.
  • 15.Singh V, Garg M, Sharma P, Sinha RJ, Kumar M.Mini incision open pyeloplasty: improvement inpatient outcome. Indian J Urol. 2015; 41: 927-34.
  • 16.Donmez MI, Carrasco A Jr, Saltzman AF, WilcoxDT. Inpatient interventions that may precludeoutpatient open pyeloplasty in infants. Int Braz JUrol. 2019; 45: 145-9.
  • 17.Kajbafzadeh AM, Tourchi A, Nezami BG, et al.Miniature pyeloplasty as a minimally invasivesurgery with less than 1 day admission in infants. JPediatr Urol. 2011; 7: 283-8.
  • 18.Sharifiaghdas FMM, Daneshpajooh A,Abbaszadeh S. Minimally invasive opendismembered pyeloplasty technique: miniatureincision, muscle-splitting dissection, and no pelvisreduction in children. Asian J Urol. 2019; 6: 290-3.
  • 19.Alizadeh F, Haghdani S, Seydmohammadi B.Minimally invasive open pyeloplasty in children:long-term follow-up. Turk J Urol. 2020; 46: 393-7.
  • 20.Wael M, Lubbad MA, Jaber A, Abuarafeh W, AlHammouri M. Pyeloplasty for a child with aretrocaval ureter: a case report. Cureus. 2023; 15:e36536.

Results of Pyeloplasty in infants Under 3 Months of Age

Yıl 2025, Cilt: 52 Sayı: 4, 883 - 890, 12.12.2025
https://doi.org/10.5798/dicletip.1841273

Öz

Objective: Ureteropelvic junction obstruction (UPJO) is a congenital anomaly most often diagnosed antenatally, with an incidence of approximately 0.1%. Open dismembered pyeloplasty remains the gold standard with high success rates. This study aimed to evaluate the functional and postoperative outcomes of miniaturized extracorporeal dismembered pyeloplasty (MExDP) in infants younger than 3 months of age.
Methods: Between November 2019 and April 2025, 58 infants under 3 months of age diagnosed with UPJO and meeting surgical criteria were retrospectively analyzed. Preoperative evaluation included ultrasonography, laboratory tests, and diuretic Tc-99m MAG3 renography. Indications included split renal function <40%, parenchymal thickness <3 mm, progressive AP diameter >40 mm, and SFU grade 3–4 hydronephrosis. All surgeries were performed by a single surgeon via a 2 cm subcostal mini-incision. Intra- and postoperative parameters were recorded.
Results: The mean age was 65.3 days (32–88). Mean incision length was 2.1 cm, and mean operative time was 65 minutes. Intraoperatively, one retrocaval ureter, two aberrant vessels, and 55 primary UPJO cases were identified. The complication rate was 3%, with no major complications. At 3 months follow-up, all patients demonstrated improvement in hydronephrosis and drainage on MAG3 renography, yielding a 100% success rate.
Conclusions: MExDP is a safe and effective surgical option for UPJO in infants younger than 3 months, offering reduced surgical trauma, smaller cosmetic scars, and outcomes comparable to laparoscopic or robotic approaches. In centers lacking robotic or advanced laparoscopic expertise, MExDP represents a feasible alternative.

Kaynakça

  • 1.Nguyen HT, Herndon CD, Cooper C, et al. TheSociety for Fetal Urology consensus statement onthe evaluation and management of antenatalhydronephrosis. J Pediatr Urol. 2010; 6: 212-31.
  • 2.Yarmohamadi A, Saeedi P, Hoghabrosadat A.Surgical Results of Anderson-Hynes DismemberedPyeloplasty Without Internal Drainage in AdultsWith Ureteroplevic Junction Obstruction. NephroUrol Mon. 2015 May; 7: e21800.
  • 3.Piaggio LA, Corbetta JP, Weller S, et al.Comparative, prospective, case–control study ofopen versus laparoscopic pyeloplasty in childrenwith ureteropelvic junction obstruction: long-termresults. Front Pediatr. 2017; 5: 10-7.
  • 4.El-Abd SA, Bastawisy MG, Ramadan AR, El-Abd AS.Pyeloplasty the dilemma: open, endoscopic, orlaparoscopic? Clin Surg. 2018; 3: 2031.
  • 5.Sharma L, Ahmed N, Bhat M, et al. Laparoscopicpyeloplasty: our experience of initial fifty two cases.J Urol Surg. 2020; 7: 125-9.
  • 6.Tufekci EC, Karabulut A, Gokce MI, et al. Mini openpyeloplasty in infants: an alternative with goodcosmetic outcomes. J Pediatr Surg. 2020; 55: 695-9.
  • 7.Hodhod A, Eid H, Fermin-Risso C, et al. Significantimprovement in hydronephrosis with pyeloplastyprior to 3 months of age in patients with antenatalsevere hydronephrosis. Int Urol Nephrol. 2024; 56:2467-73.
  • 8.Elbaset MA, Zahran MH, Sharaf MA, et al. Longterm functional success after pyeloplasty for pelvi-ureteral junction obstruction in unilateral poorlyfunctioning kidney in exclusively adults population.Urology. 2019; 131:234-9.
  • 9.Vidhya T, Rajiv P, Sripathi V. Analysis of outcomesof robot-assisted laparoscopic pyeloplasty inchildren from a tertiary pediatric center in SouthIndia. Front Pediatr. 2021; 9: 642923.
  • 10.Gadelmoula M, Abdel-Kader MS, Shalaby M, et al.Laparoscopic versus open pyeloplasty: a multi-institutional prospective study. Cent European JUrol. 2018; 71: 342-5.
  • 11.Esposito C, Cerulo M, Lepore B, et al. Robotic-assisted pyeloplasty in children: a systematic reviewof the literature. J Robot Surg. 2023; 17:1239-46.
  • 12.Sharma L, Ahmed N, Bhat M, et al. Laparoscopicpyeloplasty: our experience of initial fifty two cases.J Urol Surg. 2020; 7: 125-9.
  • 13.Cui X, Li H, Sun N, Wei X, Li Z. Mini-laparoscopicpyeloplasty versus open pyeloplasty forureteropelvic junction obstruction in infants: acomparative study. Minim Invasive Ther AlliedTechnol. 2022; 31: 473-8.
  • 14.Langreen S, Ludwikowski B, Dingemann J, et al.Laparoscopic pyeloplasty in neonates and infants issafe and efficient. Front Pediatr. 2024; 12: 1397614.
  • 15.Singh V, Garg M, Sharma P, Sinha RJ, Kumar M.Mini incision open pyeloplasty: improvement inpatient outcome. Indian J Urol. 2015; 41: 927-34.
  • 16.Donmez MI, Carrasco A Jr, Saltzman AF, WilcoxDT. Inpatient interventions that may precludeoutpatient open pyeloplasty in infants. Int Braz JUrol. 2019; 45: 145-9.
  • 17.Kajbafzadeh AM, Tourchi A, Nezami BG, et al.Miniature pyeloplasty as a minimally invasivesurgery with less than 1 day admission in infants. JPediatr Urol. 2011; 7: 283-8.
  • 18.Sharifiaghdas FMM, Daneshpajooh A,Abbaszadeh S. Minimally invasive opendismembered pyeloplasty technique: miniatureincision, muscle-splitting dissection, and no pelvisreduction in children. Asian J Urol. 2019; 6: 290-3.
  • 19.Alizadeh F, Haghdani S, Seydmohammadi B.Minimally invasive open pyeloplasty in children:long-term follow-up. Turk J Urol. 2020; 46: 393-7.
  • 20.Wael M, Lubbad MA, Jaber A, Abuarafeh W, AlHammouri M. Pyeloplasty for a child with aretrocaval ureter: a case report. Cureus. 2023; 15:e36536.
Toplam 20 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi, Tıp Eğitimi, Sağlık Hizmetleri ve Sistemleri (Diğer)
Bölüm Araştırma Makalesi
Yazarlar

Mehmet Mazhar Utangac

Onur Dede

Gönderilme Tarihi 1 Ekim 2025
Kabul Tarihi 1 Aralık 2025
Yayımlanma Tarihi 12 Aralık 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 52 Sayı: 4

Kaynak Göster

APA Utangac, M. M., & Dede, O. (2025). 3 Aydan küçük İnfantlarda yapılan Piyeloplasti sonuçlarımız. Dicle Medical Journal, 52(4), 883-890. https://doi.org/10.5798/dicletip.1841273
AMA Utangac MM, Dede O. 3 Aydan küçük İnfantlarda yapılan Piyeloplasti sonuçlarımız. diclemedj. Aralık 2025;52(4):883-890. doi:10.5798/dicletip.1841273
Chicago Utangac, Mehmet Mazhar, ve Onur Dede. “3 Aydan küçük İnfantlarda yapılan Piyeloplasti sonuçlarımız”. Dicle Medical Journal 52, sy. 4 (Aralık 2025): 883-90. https://doi.org/10.5798/dicletip.1841273.
EndNote Utangac MM, Dede O (01 Aralık 2025) 3 Aydan küçük İnfantlarda yapılan Piyeloplasti sonuçlarımız. Dicle Medical Journal 52 4 883–890.
IEEE M. M. Utangac ve O. Dede, “3 Aydan küçük İnfantlarda yapılan Piyeloplasti sonuçlarımız”, diclemedj, c. 52, sy. 4, ss. 883–890, 2025, doi: 10.5798/dicletip.1841273.
ISNAD Utangac, Mehmet Mazhar - Dede, Onur. “3 Aydan küçük İnfantlarda yapılan Piyeloplasti sonuçlarımız”. Dicle Medical Journal 52/4 (Aralık2025), 883-890. https://doi.org/10.5798/dicletip.1841273.
JAMA Utangac MM, Dede O. 3 Aydan küçük İnfantlarda yapılan Piyeloplasti sonuçlarımız. diclemedj. 2025;52:883–890.
MLA Utangac, Mehmet Mazhar ve Onur Dede. “3 Aydan küçük İnfantlarda yapılan Piyeloplasti sonuçlarımız”. Dicle Medical Journal, c. 52, sy. 4, 2025, ss. 883-90, doi:10.5798/dicletip.1841273.
Vancouver Utangac MM, Dede O. 3 Aydan küçük İnfantlarda yapılan Piyeloplasti sonuçlarımız. diclemedj. 2025;52(4):883-90.