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Prognostic Value of CCI and HALP Score in Geriatric Femur Fractures: One-Year Emergency Department Experience

Yıl 2026, Cilt: 53 Sayı: 1, 77 - 85, 10.03.2026
https://doi.org/10.5798/dicletip.1906450
https://izlik.org/JA73SA68RG

Öz

Objective: The objective of this study was to assess and contrast the predictive accuracy of the Charlson Comorbidity Index (CCI) and HALP (Hemoglobin-Albumin-Lymphocyte-Platelet) score in predicting short-term (30-day) and long-term (1-year) mortality in elderly individuals presenting to the emergency department with proximal femur fractures.
Methods: This retrospective cohort study comprised 122 patients aged 65 years and older who had radiologically verified femoral neck or intertrochanteric fractures, who underwent surgical treatment between January 2023 and December 2023. Data regarding demographics, clinical features, and laboratory results were retrieved from electronic medical systems. The primary outcomes were short-term (30-day) and long-term (1-year) mortality. Statistical analyses were performed to assess associations between mortality and CCI, HALP, and other clinical variables.
Results: The mortality rates of 30 day and 1-year were 9.8% and 29.5%. One-year mortality showed a strong correlation with increased age (p<0.001) and lower serum albumin levels (p=0.030). The HALP score was lower in deceased patients, however, this difference did not reach statistical significance (p=0.244). No significant association was observed between CCI and mortality at either 30-days or 1-year. ICU admission and prolonged hospital stay were strongly correlated with elevated 30-day mortality rates (p<0.001 and p=0.003, respectively).
Conclusion: Advanced age and hypoalbuminemia were independently associated with increased 1-year mortality. While HALP and CCI scores showed numerical differences between survivors and non-survivors, only albumin reached statistical significance. ICU admission and extended hospitalization were significant predictors of short-term mortality. These findings highlight the need for multidimensional assessment tools combining clinical, nutritional, and inflammatory parameters to improve outcome prediction in elderly femur fracture patients.

Etik Beyan

The study was approved by the Ethics Committee for Noninterventional Studies on June 18, 2024, with decision number 230.

Kaynakça

  • 1.Delgadillo C.A., Rojas Lievano J. & Olarte C.M.Geriatric distal femoral fractures: post-operativecomplications and nine-year mortality—aretrospective analysis of two tertiary traumacentres. International Orthopaedics (SICOT) 48,841–848 (2024). https://doi.org/10.1007/s00264-023-06075-3
  • 2.Charlson ME, Pompei P, Ales KL, MacKenzie CR. Anew method of classifying prognostic comorbidity inlongitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373-83. doi: 10.1016/0021-9681(87)90171-8. PMID: 3558716.
  • 3.Zhang DL, Cong YX, Zhuang Y, Xu X, Zhang BF. Age-adjusted Charlson comorbidity index predictspostoperative mortality in elderly patients with hipfracture: A prospective cohort. Front Med(Lausanne). 2023 Mar 7;10:1066145. doi:10.3389/fmed.2023.1066145. PMID: 36960340;PMCID: PMC10027731.
  • 4.Kalan Farmanfarma K, Yarmohammadi S,Fakharian E, et al. Prognostic Factors of Hip Fracturein Elderly: A Systematic Review. Int J Prev Med. 2024Aug 30;15:42. doi: 10.4103/ijpvm.ijpvm_169_23.PMID: 39381356; PMCID: PMC11460988.
  • 5.Wang Z, Liu H, Liu M. The hemoglobin, albumin,lymphocyte, and platelet score as a useful predictorfor mortality in older patients with hip fracture.Front Med (Lausanne). 2025;12:1450818.Published 2025 Feb 18. doi:10.3389/fmed.2025.1450818
  • 6.Zhang C, Peng W, Ning M, et al. Correlationbetween hemoglobin, albumin, lymphocyte, andplatelet score and short-term mortality in criticallyill patients. J Health Popul Nutr. 2025;44(1):36.Published 2025 Feb 8. doi:10.1186/s41043-025-00759-9
  • 7.Gao Y, Zhou S, Gao W, et al. Preoperative Indicatorsfor 1-year Mortality in Elderly Individuals FollowingHip Fracture Surgery Under A MultidisciplinaryTeam Co-Management Model: A Single-CentreRetrospective Observational Study. Geriatr OrthopSurg Rehabil. 2025;16:21514593251356135.Published 2025 Jun 25. doi:10.1177/21514593251356135
  • 8.Dyer SM, Crotty M, Fairhall N, et al. A criticalreview of the long-term disability outcomes following hip fracture. BMC Geriatr. 2021;21(1):658. doi:10.1186/s12877-021-02633-5
  • 9.Inoue T, Kuwagata Y, Yamamoto S, et al. Advancedage as a risk factor for mortality after hip fracture inelderly patients: A multicenter retrospective study. JOrthop Sci. 2022;27(3):567-72.doi:10.1016/j.jos.2021.09.011
  • 10.Cecchi F, Pancani S, Antonioli D, et al. Predictivevalue of age-adjusted Charlson Comorbidity Indexon mortality after hip fracture surgery in elderlypatients. Aging Clin Exp Res. 2021;33(9):2423-30.doi:10.1007/s40520-021-01877-y
  • 11.Kim J, Cho J, Lee JH, et al. The predictive ability ofCharlson Comorbidity Index for mortality after hipfracture surgery: A nationwide cohort study. GeriatrGerontol Int. 2024;24(2):175-81.doi:10.1111/ggi.14678
  • 12.Kim JW, Kim R, Jang WY, et al. Serum albuminlevel as a predictor of mortality in patients with hipfracture: A systematic review and meta-analysis. JBone Metab. 2022;29(1):1-9.doi:10.11005/jbm.2022.29.1.1
  • 13.Li Y, Li J, Wang Y, et al. Prognostic value of HALPscore in elderly trauma patients: A retrospectivecohort study. Front Med (Lausanne).2023;10:1163217.doi:10.3389/fmed.2023.1163217
  • 14.Zhang Z, Tang Y, Ma W, et al. Hemoglobin,albumin, lymphocyte, and platelet (HALP) score as apredictive factor in geriatric femoral fracturepatients: A large cohort study. Aging Clin Exp Res.2023;35(8):2019-27. doi:10.1007/s40520-023-02333-7
  • 15.González-Zabaleta J, Guerra-Farfán E, Pérez-García MJ, et al. ICU admission and mortality inelderly patients after hip fracture surgery: Riskfactors and outcomes. Injury. 2021;52(11):3243-9.doi:10.1016/j.injury.2021.07.027

Geriatrik Femur Kırıklarında CCI ve HALP Skorunun Prognostik Değeri: Bir Yıllık Acil Servis Tecrübesi

Yıl 2026, Cilt: 53 Sayı: 1, 77 - 85, 10.03.2026
https://doi.org/10.5798/dicletip.1906450
https://izlik.org/JA73SA68RG

Öz

Amaç: Bu çalışmada, acil servise proksimal femur kırığı ile başvuran geriyatrik hastalarda Charlson Komorbidite İndeksi (CCI)ve HALP (Hemoglobin, Albümin, Lenfosit, Trombosit) skorunun 30 günlük ve 1 yıllık mortaliteyi öngörmedekiprognostik değerinin değerlendirilmesi amaçlandı.
Yöntemler: Retrospektif kohort tasarımla yürütülen bu çalışmaya, Ocak 2023–Aralık 2023 tarihleri arasında cerrahi tedavi uygulanmış, radyolojik olarak doğrulanmış femur boyun veya intertrokanterik kırığı olan 65 yaş üstü 122 hasta dâhil edildi. Demografik, klinik ve laboratuvar verileri elektronik kayıt sisteminden elde edildi. Birincil sonuçlar 30 günlük ve 1 yıllık mortaliteydi. CCI, HALP ve diğer klinik değişkenlerle mortalite arasındaki ilişkiler analiz edildi.
Bulgular: 30 günlük mortalite %9.8, 1 yıllık mortalite %29.5 olarak saptandı. 1 yıllık mortalite; ileri yaş (p<0.001) ve düşük serum albümin düzeyleriyle (p=0.030) anlamlı şekilde ilişkiliydi. Ölen hastalarda HALP skoru daha düşük bulunmasına rağmen, bu fark istatistiksel olarak anlamlı değildi(p=0,244). CCI skoru ile mortalite arasında anlamlı bir ilişki gözlenmedi. Yoğun bakım ihtiyacı ve uzun hastanede kalış süresi 30 günlük mortalite ile anlamlı ilişki gösterdi (sırasıyla p<0.001 ve p=0.003).
Sonuç: İleri yaş ve hipoalbüminemi, 1 yıllık mortalite açısından bağımsız risk faktörleri olarak saptandı. HALP ve CCI skorları sayısal farklılık gösterse de yalnızca albümin düzeyi anlamlıydı. Yoğun bakım gereksinimi ve uzamış hastane yatışı erken dönem mortalite ile ilişkilendirildi. Bu bulgular, geriyatrik femur kırığı hastalarında prognozun daha doğru belirlenmesi için klinik, beslenme ve inflamasyon parametrelerini birleştiren çok boyutlu değerlendirme araçlarına ihtiyaç olduğunu göstermektedir.

Kaynakça

  • 1.Delgadillo C.A., Rojas Lievano J. & Olarte C.M.Geriatric distal femoral fractures: post-operativecomplications and nine-year mortality—aretrospective analysis of two tertiary traumacentres. International Orthopaedics (SICOT) 48,841–848 (2024). https://doi.org/10.1007/s00264-023-06075-3
  • 2.Charlson ME, Pompei P, Ales KL, MacKenzie CR. Anew method of classifying prognostic comorbidity inlongitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373-83. doi: 10.1016/0021-9681(87)90171-8. PMID: 3558716.
  • 3.Zhang DL, Cong YX, Zhuang Y, Xu X, Zhang BF. Age-adjusted Charlson comorbidity index predictspostoperative mortality in elderly patients with hipfracture: A prospective cohort. Front Med(Lausanne). 2023 Mar 7;10:1066145. doi:10.3389/fmed.2023.1066145. PMID: 36960340;PMCID: PMC10027731.
  • 4.Kalan Farmanfarma K, Yarmohammadi S,Fakharian E, et al. Prognostic Factors of Hip Fracturein Elderly: A Systematic Review. Int J Prev Med. 2024Aug 30;15:42. doi: 10.4103/ijpvm.ijpvm_169_23.PMID: 39381356; PMCID: PMC11460988.
  • 5.Wang Z, Liu H, Liu M. The hemoglobin, albumin,lymphocyte, and platelet score as a useful predictorfor mortality in older patients with hip fracture.Front Med (Lausanne). 2025;12:1450818.Published 2025 Feb 18. doi:10.3389/fmed.2025.1450818
  • 6.Zhang C, Peng W, Ning M, et al. Correlationbetween hemoglobin, albumin, lymphocyte, andplatelet score and short-term mortality in criticallyill patients. J Health Popul Nutr. 2025;44(1):36.Published 2025 Feb 8. doi:10.1186/s41043-025-00759-9
  • 7.Gao Y, Zhou S, Gao W, et al. Preoperative Indicatorsfor 1-year Mortality in Elderly Individuals FollowingHip Fracture Surgery Under A MultidisciplinaryTeam Co-Management Model: A Single-CentreRetrospective Observational Study. Geriatr OrthopSurg Rehabil. 2025;16:21514593251356135.Published 2025 Jun 25. doi:10.1177/21514593251356135
  • 8.Dyer SM, Crotty M, Fairhall N, et al. A criticalreview of the long-term disability outcomes following hip fracture. BMC Geriatr. 2021;21(1):658. doi:10.1186/s12877-021-02633-5
  • 9.Inoue T, Kuwagata Y, Yamamoto S, et al. Advancedage as a risk factor for mortality after hip fracture inelderly patients: A multicenter retrospective study. JOrthop Sci. 2022;27(3):567-72.doi:10.1016/j.jos.2021.09.011
  • 10.Cecchi F, Pancani S, Antonioli D, et al. Predictivevalue of age-adjusted Charlson Comorbidity Indexon mortality after hip fracture surgery in elderlypatients. Aging Clin Exp Res. 2021;33(9):2423-30.doi:10.1007/s40520-021-01877-y
  • 11.Kim J, Cho J, Lee JH, et al. The predictive ability ofCharlson Comorbidity Index for mortality after hipfracture surgery: A nationwide cohort study. GeriatrGerontol Int. 2024;24(2):175-81.doi:10.1111/ggi.14678
  • 12.Kim JW, Kim R, Jang WY, et al. Serum albuminlevel as a predictor of mortality in patients with hipfracture: A systematic review and meta-analysis. JBone Metab. 2022;29(1):1-9.doi:10.11005/jbm.2022.29.1.1
  • 13.Li Y, Li J, Wang Y, et al. Prognostic value of HALPscore in elderly trauma patients: A retrospectivecohort study. Front Med (Lausanne).2023;10:1163217.doi:10.3389/fmed.2023.1163217
  • 14.Zhang Z, Tang Y, Ma W, et al. Hemoglobin,albumin, lymphocyte, and platelet (HALP) score as apredictive factor in geriatric femoral fracturepatients: A large cohort study. Aging Clin Exp Res.2023;35(8):2019-27. doi:10.1007/s40520-023-02333-7
  • 15.González-Zabaleta J, Guerra-Farfán E, Pérez-García MJ, et al. ICU admission and mortality inelderly patients after hip fracture surgery: Riskfactors and outcomes. Injury. 2021;52(11):3243-9.doi:10.1016/j.injury.2021.07.027
Toplam 15 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi, Tıp Eğitimi, Sağlık Hizmetleri ve Sistemleri (Diğer)
Bölüm Araştırma Makalesi
Yazarlar

Hasan Mansur Durgun Bu kişi benim

Emin Özkul

Gönderilme Tarihi 13 Ekim 2025
Kabul Tarihi 16 Ocak 2026
Yayımlanma Tarihi 10 Mart 2026
DOI https://doi.org/10.5798/dicletip.1906450
IZ https://izlik.org/JA73SA68RG
Yayımlandığı Sayı Yıl 2026 Cilt: 53 Sayı: 1

Kaynak Göster

APA Durgun, H. M., & Özkul, E. (2026). Prognostic Value of CCI and HALP Score in Geriatric Femur Fractures: One-Year Emergency Department Experience. Dicle Medical Journal, 53(1), 77-85. https://doi.org/10.5798/dicletip.1906450
AMA 1.Durgun HM, Özkul E. Prognostic Value of CCI and HALP Score in Geriatric Femur Fractures: One-Year Emergency Department Experience. diclemedj. 2026;53(1):77-85. doi:10.5798/dicletip.1906450
Chicago Durgun, Hasan Mansur, ve Emin Özkul. 2026. “Prognostic Value of CCI and HALP Score in Geriatric Femur Fractures: One-Year Emergency Department Experience”. Dicle Medical Journal 53 (1): 77-85. https://doi.org/10.5798/dicletip.1906450.
EndNote Durgun HM, Özkul E (01 Mart 2026) Prognostic Value of CCI and HALP Score in Geriatric Femur Fractures: One-Year Emergency Department Experience. Dicle Medical Journal 53 1 77–85.
IEEE [1]H. M. Durgun ve E. Özkul, “Prognostic Value of CCI and HALP Score in Geriatric Femur Fractures: One-Year Emergency Department Experience”, diclemedj, c. 53, sy 1, ss. 77–85, Mar. 2026, doi: 10.5798/dicletip.1906450.
ISNAD Durgun, Hasan Mansur - Özkul, Emin. “Prognostic Value of CCI and HALP Score in Geriatric Femur Fractures: One-Year Emergency Department Experience”. Dicle Medical Journal 53/1 (01 Mart 2026): 77-85. https://doi.org/10.5798/dicletip.1906450.
JAMA 1.Durgun HM, Özkul E. Prognostic Value of CCI and HALP Score in Geriatric Femur Fractures: One-Year Emergency Department Experience. diclemedj. 2026;53:77–85.
MLA Durgun, Hasan Mansur, ve Emin Özkul. “Prognostic Value of CCI and HALP Score in Geriatric Femur Fractures: One-Year Emergency Department Experience”. Dicle Medical Journal, c. 53, sy 1, Mart 2026, ss. 77-85, doi:10.5798/dicletip.1906450.
Vancouver 1.Hasan Mansur Durgun, Emin Özkul. Prognostic Value of CCI and HALP Score in Geriatric Femur Fractures: One-Year Emergency Department Experience. diclemedj. 01 Mart 2026;53(1):77-85. doi:10.5798/dicletip.1906450