The frequency of polyneuropathy and comparison of laboratory parameters in patients with multiple myeloma
Öz
Objective: Multiple myeloma(MM) is a B-cell neoplasia, characterized by clonal expansion of malignant plasma cells in bone marrow. Polyneuropathy (PN) is the most important complications in the treatment of MM. The aim of our study is to find out whether the lab parameters and the incidence of PN, are markers in MM patients or not.
Methods: Totally 70 patients (31 male, 39 female) who presented to hematology outpatient department were retrospectively evaluated. Pre-treatment laboratory parameters and electromyography records of the patients taken from the file.
Results: 15.7% of the cases the diagnosis was immediately available PN. Levels of β2 microglubin, uric acid, total protein, calcium, ALT, AST, creatinine, LDH and albumin levels didn’t differ significantly between two groups (p>0.05).
Conclusion: Presence or development of PN in MM and its readiness to be used as an early marker, will obviously facilitate the treatment and follow-up of MM.
Key words: Multiple myeloma, polyneuropathy, electromyography
Anahtar Kelimeler
Kaynakça
- Decaux O, Laurat E, Perlat A, et al. Systemic manifestations of monoclonal gammopathy. Eur J Intern Med 2009;20:457-461.
- Ramchandren S, Lewis RA. Monoclonal gammopathy and
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Ayrıntılar
Birincil Dil
Türkçe
Konular
-
Bölüm
-
Yazarlar
Mesut Ayer
Bu kişi benim
Kenan Çelik
Bu kişi benim
Fatih Berkil
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Hürtan Acar
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Aylin Ayer
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Ayşegül Sakin
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Fuat Şar
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Yayımlanma Tarihi
8 Ocak 2016
Gönderilme Tarihi
8 Ocak 2016
Kabul Tarihi
-
Yayımlandığı Sayı
Yıl 2015 Cilt: 42 Sayı: 4