The predictive value of three-dimensional Doppler ultrasonography in determining implantation in patients underwent in vitro fertilization
Öz
Objective: The aim of this study is to evaluate the relationship between endometrial and sub-endometrial blood flow and implantation rate in patients whose undergone in vitro fertilization.
Methods: A prospective study was conducted. Long protocol and antagonist regimens were administered to the patients. Endometrial and sub-endometrial blood flow was evaluated by using 3 dimensional Doppler ultrasonography on the day of oocyt retrieval measurement. For comparison pregnant and non-pregnant women in terms of endometrial and sub-endometrial blood flow, t test was used. The p value was considered statistically meaningful as <0.05.
Results: Endometrial and sub-endometrial blood flow was not different between pregnant and non-pregnant women in both groups (p>0.05). In long protocol group, the number of embryo was greater in pregnant women than non-pregnant women (p=0.012). The number of transferred embryo increased pregnancy rate almost 3.5 fold (p=0.002).
Conclusion: The endometrial and subendometrial blood flow is not reliable factor in prediction pregnancy or implantation.
Key words: Doppler ultrasonography, in vitro fertilization, pregnant women
Anahtar Kelimeler
Kaynakça
- Ng EH, Chan CC, Tang OS, Ho PC. Comparison of 2-dimensional,
- -dimensional, and vascular ultrasonographic parameters for endometrial receptivity between 2 consecutive stimulated in vitro fertilization cycles. J Ultrasound Med. 2007;26:931-939.
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- immune histochemical evaluation of endometrium in fertile and infertile women with implantation failure. Dicle Medical Journal 2012;39:269-295.
- Gannon BJ, Carati CJ, Verco CJ. Endometrial perfusion across the normal human menstrual cycle assessed by laser Doppler fluxmetry. Hum Reprod. 1997;12:132-139.
- Raine-Fenning NJ, Campbell BK, Clewes JS, Kendall NR, Johnson IR. The reliability of virtual organ computer-aided analysis (VOCAL) for the semi quantification of ovarian, endometrial and subendometrial perfusion. Ultrasound Obstet Gynecol 2003;22:633-639.
- Chien LW, Au HK, Chen PL, et al. Assessment of uterine receptivity by the endometrial-subendometrial blood flow distribution pattern in women undergoing in vitro fertilization-embryo transfer. Fertil Steril 2002;78:245-251.
- Hsieh YY, Chang FC, Tsai HD. Doppler evaluation of the uterine and spiral arteries from different sampling sites and phases of the menstrual cycle during controlled ovarian hyper-stimulation.
Ayrıntılar
Birincil Dil
Türkçe
Konular
-
Bölüm
-
Yayımlanma Tarihi
8 Ocak 2016
Gönderilme Tarihi
8 Ocak 2016
Kabul Tarihi
-
Yayımlandığı Sayı
Yıl 2015 Cilt: 42 Sayı: 4