Stereotactic biopsy of the brain mass lesions: a tertiary hospital experience
Öz
Objectives: Stereotactic
biopsy (SB) is a guided technic performed for the lesions on eloquent brain
areas. The aim of this study is revealing the diagnostic reliability and the
risk ratio of SB.
Methods:
Data of patients performed SB due to various intracranial lesions was collected
retrospectively. The study took place in Department of Neurosurgery, Gazi
University Faculty of Medicine between February 2004 and April 2014. Data
analysis performed in terms of age, gender, lesion location, histopathology,
and outcomes of surgery.
Results:
Sixty percent of patients were male (146 patients) and forty percent of them
was female (96 patients), between the ages of 11 and 84 years (mean age of 49
years) with a total number of 242. Mortality and morbidity rates were
respectively 0.4% and 3.3%. The overall diagnostic yield was 81% (196
patients), while 19% (46 patients) had nonspecific results, which did cannot
lead any further therapy. Among 36 patients of whom pathologies were confirmed
with an excisional biopsy, the diagnostic accuracy was shown in 24 patients
(67%).
Conclusions: Beside low risk of mortality and morbidity, the high rate of non-diagnostic results and low rate of diagnostic accuracy are the limitations of SB, which should be improved by careful skills to obtain more specimen, sophisticated software for planning, and intraoperative pathological examination for guaranteeing.
Anahtar Kelimeler
Kaynakça
- 1. Horsley V, Clarke RH. The structure and functions of the cerebellum examined by a new method. Brain. 1908; 31: 45–124.
- 2. Schulder M. Handbook of Stereotactic and Functional Neurosurgery, 1st edn. New Jersey Medical School, USA: CRC Press, 2003: 1-608
- 3. Burger PC, Nelson JS. Stereotactic brain biopsies. Pathol Lab Med. 1997; 121: 477-80.
- 4. Krieger MD, Chandrasoma PT, Zee CS, Apuzzo ML. Role of stereotactic biopsy in the diagnosis and management of brain tumors. Seminars in surgical oncology. John Wiley & Sons, Inc. 1998; 14: 1-11.
- 5. Chandrasoma PT, Smith MM, Apuzzo ML. Stereotactic biopsy in the diagnosis of brain masses: comparison of results of biopsy and resected surgical specimen. Neurosurgery. 1989; 24: 160-5.
- 6. Savas A. Beyin Biyopsisi – Stereotaksik Cerrahi Tekniği. Society of Turkish Neurosurgery, Basic Neurosurgery, 2nd edn: 1999, 2010.
- 7. Kim JE, Kim DG, Paek SH, Jung HW. Stereotactic biopsy for intracranial lesions: reliability and its impact on the planning of treatment. Acta neurochirurgica. 2003; 145: 547-55.
- 8. Fritsch MJ, Leber MJ, Gossett L, Lulu BA, Hamilton AJ. Stereotactic biopsy of intracranial brain lesions. High diagnostic yield without increased complications: 65 consecutive biopsies with early postoperative CT scans. Stereotact Funct Neurosurg. 1998; 71: 36-42.
Ayrıntılar
Birincil Dil
Türkçe
Konular
-
Bölüm
Araştırma Makalesi
Yazarlar
Ayfer Aslan
Bu kişi benim
0000-0002-5413-7833
Türkiye
Özgür Öcal
Bu kişi benim
0000-0002-8985-2626
Türkiye
Ömer Hakan Emmez
Bu kişi benim
0000-0002-3290-179X
Türkiye
Gökhan Kurt
Bu kişi benim
0000-0002-2773-056X
Türkiye
Şükrü Aykol
Bu kişi benim
0000-0001-7896-1563
Türkiye
Yayımlanma Tarihi
5 Eylül 2018
Gönderilme Tarihi
4 Eylül 2018
Kabul Tarihi
-
Yayımlandığı Sayı
Yıl 2018 Cilt: 45 Sayı: 3