Dermoid Kist Nedeniyle Tedavi Edilen 114 Olgunun Retrospektif Analizi

Öz

Amaç: Bu çalışmanın amacı; hastanemizde cerrahi tedavi uygulanan dermoid kist olgularının klinik bulguları, tanı yöntemleri, tümör belirteç düzeyleri, cerrahi tedavi yaklaşımları ve nihai patoloji sonuçlarını değerlendirmektir. Yöntemler: Çalışmamız retrospektif olarak planlanmıştır. Hastanemiz elektronik kayıt sisteminden dermoid kist nedeniyle tedavi edilen toplam 114 hasta çalışmaya dâhil edildi. Hasta dosyalarından demografik verilerin yanı sıra, pre-operatif klinik bulgular, tümör boyutu, ultrasonografik özellikleri, tümör belirteç sonuçları, cerrahi tedavi şekli (laparatomi-laparoskopi), uygulanan cerrahi tedavi şekli (kistektomi, ooforektomi, salpingo-ooforektomi, total abdominal histerektomi-salpingo-ooforektomi) ve patoloji sonuçları not edildi. Bulgular: Hastalarımızın ortalama yaşı 33,59±12,79 yıl (11 ile 70 yaş arası) olarak tespit edildi. Hastaneye başvuru sırasında en sık tespit edilen şikâyetin 32 hastada (%28,07) tespit edilen karın ağrısı olduğu görüldü. 70 hastanın (%38,59) ise insidental olarak tespit edildiği görüldü. Ultrasonografik incelemede ortalama kist boyutunun 47,70±48,49 cm2 olduğu tespit edildi (12 ile 300 cm2 arasında). Çalışmaya dâhil edilen 114 hastanın sadece 12’sinde (%10,52) Ca 125,29 hastada (%25,43) ise Ca 19-9 düzeyinin normal değerin üstünde olduğu saptandı. Nihai patoloji sonuçlarına göre en sık tespit edilen sonuç 103 hastada (%90,4) görülen dermoid kist idi. Diğer histopatolojik sonuçlar ise immatür teratom, skuamöz hücreli karsinom ve seröz karsinom idi. Sonuç: Ovaryan dermoid kistler genelde benign neoplazmlar olup nadiren malign transformasyon gösterirler. Tümör belirteçleri bu ayrımı yapmada tam anlamıyla yeterli olmamaktadır. Ancak özellikle ileri yaşlarda olan hastalarda malignite yönünden risk artışı olduğundan dikkatli olunmalıdır.

Anahtar Kelimeler

• Dermoid kist, ultrasonografi, yaş, histopatolojik içerik

Retrospective Analysis of 114 Cases Treated for Dermoid Cyst

Öz

Objective: The purpose of this study is to evaluate the clinical findings, tumor markers, surgical treatment ap­proaches and final pathological results of the dermoid cyst subjects treated at our hospital. Methods: The study was planned retrospectively. 114 subjects with dermoid cyst were included from our hos­pitals electronic log system. Along with the demographic data’s, pre-operative clinical findings, tumor sizes, ul­trasonographic characteristics, tumor marker results, surgical treatment method (laparotomy-laparoscopy), administered surgical treatment procedure (cystectomy, oopherectomy, salpingo-oopherectomy, total abdominal hysterectomy-salpingo-oopherectomy) and pathology re­sults were recorded from the patient files. Results: Mean age of the patients was 33.59±12.79 years (11-70). Abdominal pain was observed in 32 patients (%28.07) as the most common complaint during hospi­tal admission. 70 patients (%38.59) were determined in­cidentally. Average cyst size was 47.70±48.49 cm2 dur­ing the ultrasonographic examination. Ca 125 level was higher than normal limits in only 12 (%10.52) patients and Ca 19-9 level was higher in only 29 (%25.43) of patients. The most common final histopathological diagnosis was dermoid cyst in 103 (%90.40) patients. Other histopatho­logical diagnoses were immature teratoma, squamous cell carcinoma and serous carcinoma. Conclusion: Ovarian dermoid cysts are usually benign neoplasms and rarely show malign transformations. Tu­mor markers are not fairly enough to make discrimina­tions. However especially in older patients treatment should be done cautiously due to the raised risk of ma­lignity.

Anahtar Kelimeler

• Dermoid cyst, ultrasonography, age, histopathologic content

Kaynakça

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