Dentinogenic ghost cell tumour of mandible: Case report

Öz

A 67 year old man with a gingival mass of six months duration was evaluated by aspiration cytology and excisional biopsy. Cytologic findings showed degenerated benign epithelial cells reminiscent of benign odontogenic keratocyst. However, the excisional biopsy was quite remarkable with odontogenic epithelium showing aberrant keratinization, i.e., ghost cells and dysplastic dentin that were features of dentinogenic ghost cell tumor. There was no sign of malignancy. After local resection of the mass, there was not any complication or recurrence six months later.

Anahtar Kelimeler

• Odontogenic tumor, gingiva mass, dentinogenic ghost cell tumor

Mandibulada Dentinojenik Ghost Hücreli Tümör: Olgu sunumu

Öz

Altı aydır gingivada kitlesi olan 67 yaşındaki erkek hasta aspirasyon sitolojisi ve eksizyonel biyopsi ile değerlendirildi. Sitolojik bulgularda benign odontojenik keratositleri anımsatan dejenere benign epitelyal hücreler görüldü. Fakat eksizyonel biyopsi, dentinojenik ghost hücreli tümör özelliklerinden olan aberant keratinizasyon, ghost hücreleri ve displastik dentin görülen odontejenik epitel açısından oldukça belirgindi. Malignite belirtisi yoktu. Kitlenin lokal rezeksiyonundan sonraki 6 aylık dönemde herhangi bir komplikasyon veya rekürrens izlenmedi.

Anahtar Kelimeler

• Odontojenik tümör, gingiva kitlesi, dentinojenik ghost hücreli tümör

Kaynakça

1. Quinn M, BraceM. Dentinogenic ghost cell tumor of the max- illa. Otolaryngology-Head Neck Surg 2008;139(4):604-5.
2. Praetorius F, Ledesma-Montes C. Dentinogenic ghost cell tu- mour. World Head Organization Classification of Tumours. Pathology & Genetics Head and Neck Tumours. Edited by Leon Barnes, John W. Evenson, Peter Reichart, David Sid- ransky. IARCPress, Lyon, 2005:314.
3. Tomich CE. Calsifying odontogenic cyst and dentinogenic ghost cell tumor. Oral Maxillofac Surg Clin North Am 2004;16(2):391-7.
4. Mori M, Kasai T, Nakai M, et al. Dentinogenic ghost cell tumor:histologic aspects, immunohistocemistry, lectin binding profiles, and biophysical studies. Oral Oncology 2000;36(1):134-43.
5. Gorlin RJ, Pindborg JJ, Clausen FP. Et al.The calcifying odontegenic cyst: A possible analogue of the cutaneous cal- cifying epithelioma of Malherbe. Oral Surg Oral Med Oral Pathol Oral Radiol endod 1962;15(9):1235-43.
6. Ellis GL. Odontogenic ghost cell tumor. Semin Diagn Pathol 1999;16(2):288-92.
7. Alice E. Curran.Peripheral odontogenic tumors.Oral Maxil- lofacial Surg Clin N Am 2004;16(2):399-408.
8. Stone CH, Gaba AR, Benninger MS, et al. Odontogenic ghost cell tumor: A case report with cytological findings. Diagn Cytopathol 1998;18(2):199-203.