Bacteremia caused by Campylobacter jejuni subsp. jejuni in a patient with liver cirrhosis: A case report

Öz

Campylobacter türleri Gram negatif, sporsuz, kapsülsüz ve oksidaz pozitif bakterilerdir. Bunlar arasında insan ve hayvanlarda en çok enfeksiyon oluşturan türler Campylobacter jejuni, Campylobacter fetus ve Campylobacter coli\'dir. İnsanda intestinal ve ekstra intestinal hastalıklara sebep olabilmektedirler. İntestinal olgularda en sık saptanan tip C.jejuni subsp. jejuni olmakla birlikte “Centers for Disease Control and Prevention (CDC)” a bildirilen bakteriyemi olgularının hemen tamamında etken C.fetus subsp. fetus\'tur. C.jejuni ile enfekte hastaların %1 ‘inden azında ise bakteriyemi görülebilmektedir. Kronik karaciğer hastalığı olan hepatobiliyer ya da gastrointestinal kanserli ve HIV enfekte hastalarda bakteriyemi insidansı yüksektir. Bu olguda kan kültüründen C.jejuni subsp. jejuni\'nin izole edildiği, 47 yaşında, karaciğer sirozlu bir erkek hasta sunulmaktadır.

Anahtar Kelimeler

• Campylobacter jejuni, bakteriyemi, siroz

Bacteremia caused by Campylobacter jejuni subsp. jejuni in a patient with liver cirrhosis: A case report

Öz

Campylobacter species are Gram-negative, oxidase-positive, non-spore forming and encapsulated bacteria. Among these, most infectious agents seen in human and animal species are Campylobacter jejuni, Campylobacter fetus and Campylobacter coli. They can cause intestinal and extra-intestinal diseases in humans. Although C.jejuni subsp. jejuni is the most frequently identified agent in intestinal cases, C.fetus subsp. fetus is the most frequently identified agent in almost all bacteremia cases that reported to CDC (Centers for Disease Control and Prevention).Bacteremia can be seen less than 1 % of patients infected with C.jejuni. Incidence of bacteremia is higher among patients with chronic liver diseases, hepatobiliary or gastrointestinal cancers and HIV-infected patients. In this case report, we present a previously diagnosed 47-years-old liver cirrhosis patient whom C.jejuni subsp. jejuni isolated from blood culture.

Anahtar Kelimeler

• Campylobacter jejuni, bacteremia, cirrhosis

Kaynakça

1. Perçin D. İnsanlarda Kampilobakteriyoz. In: Doğanay M, Al- tındaş N, eds. Zoonozlar Hayvanlardan İnsanlara Bulaşan Enfeksiyonlar. Ankara: Bilimsel Tıp Yayınevi, 2009:121-8.
2. Pacanowski J, Lalande V, Lacombe, et al. Campylobacter bacteremia: clinical features factors associated with fetal outcome. Clin Infect Dis 2008;47(6):790-6.
3. Başustaoğlu AC, Kılıç A, Özyurt M, Turhan V, Hasçelik G. Campylobacter jejuni spp. jejuni’ye bağlı bir bakteriyemi olgusu. Türk Hij Den Biyol Derg 2001;58(2):67-70.
4. Allos BM. Campylobacter jejuni infections: update on emerg- ing issues and trends. Clin Infect Dis 2001;32(8):1201-6.
5. Monselise A, Blickstein D, Ostfeld I, Segal R, Weinberger M. A case of cellulitis complicating Campylobacter jejuni subspecies jejuni bacteremia and review of the literature. Eur J Clin Microbiol Infect Dis 2004;23(9):718-21.
6. Feedoroff B, Lauhio A, Elilström P, Rautelin H. A nationwide study of Campylobacter jejuni and Campylobacter coli bacteremia in finland over a 10-year period, 1998-2007, with special reference to clinical characteristics and anti- microbial susceptibility. Clin Infect Dis 2011;53(8):99-106.
7. Alfredson DA, Korolik V. Antibiotic resistance and resis- tance mechanisms in Campylobacter jejuni and Campylo- bacter coli. FEMS Microbiol Lett 2007;277(2):123-32.