-

Öz

Objective: To evaluate the histopathological results of cases who presented with an eyelid mass and underwent mass excision.Methods: The histopathological results of 107 cases, who underwent eyelid mass excision between May 2011 and March 2014 were retrospectively analyzed. Age and sex, mass localization, operative technique, and histopathological results were recorded.Results: Of 107 subjects included in the study, 61 were male and 46 were female, with a mean age of 49.44±19.81 years. The distribution of benign eyelid tumors were as follows: 37 (37.8%) squamous papillomas, 19 (19.4%) intradermal nevus, 9 (9.2%) seborrheic keratosis, 7 (7.1%) epidermal inclusion cyst, 6 (6.1%) inflammatory lesions, 5 (5.1%) suderiferous cysts, 5 (5.1%) capillary hemangiomas, 3 (3.1%) xanthelasma, 3 (3.1%) fibromas, 1 (1.0%) moll gland cyst, 1 (1.0%) chondroid syringoma, 1 (1.0%) dermoid cyst, and 1 (1.0%) actinic keratosis. Malignant eyelid tumors included 8 (88.9%) cases of basal cell carcinomas and 1 (11.1%) squamous cell carcinoma.Conclusion: In this study squamous papilloma was the most common benign eyelid tumor followed by intradermal nevus. Basal cell carcinoma was the most common malignant eyelid tumor followed by squamous cell carcinoma

Anahtar Kelimeler

• Eyelid, mass, histopathology, benign, malignant, tumor

Primer göz kapağı tümörlerinde histopatoloji sonuçları

Öz

Amaç: Göz kapağında kitle nedeniyle başvuran ve kitle eksizyonu yapılan olguların histopatolojik sonuçlarını de- ğerlendirmek. Yöntemler: Mayıs 2011 ile Mart 2014 tarihleri arasında göz kapağı kitlesi eksizyonu yapılan 107 olgunun histopatolojik sonuçları retrospektif olarak değerlendirildi. Vakaların yaşı ve cinsiyeti, kitlenin lokalizasyonu, ameliyat tekniği ve histopatolojik tanıları kaydedildi. Bulgular: Çalışmaya dahil edilen 107 hastanın 61’i erkek, 46’sı kadın olup yaş ortalaması 49,44±19,81 yıl idi. İyi huylu göz kapağı tümörlerinin histopatolojik sonuçlarına göre dağılımı skuamöz papillom 37 olgu (%37,8), intradermal nevüs 19 olgu (%19,4), seboreik keratoz 9 olgu (%9,2), epidermal inklüzyon kisti 7 olgu (%7,1), inflamatuar lezyon 6 olgu (%6,1), suderiferöz kist 5 olgu (%5,1), kapiller hemanjiom 5 olgu (%5,1), ksantelezma 3 olgu (%3,1), fibrom 3 olgu (%3,1), moll gland kisti 1 olgu (%1,0), kondroid syringoma 1 olgu (%1,0), dermoid kist 1 olgu (%1,0), aktinik keratoz 1 olgu (%1,0) idi. Kötü huylu göz kapağı tümörlerinin histopatolojik sonuçlarına göre dağılımı bazal hücreli karsinom 8 olgu (%88,9), yassı hücreli karsinom 1 olgu (%11,1) idi. Sonuç: Çalışmamızda skuamöz papillom en sık görülen iyi huylu kapak tümörüdür ve bunu ikinci sırada intradermal nevüs izlemektedir. Kötü huylu kapak tümörlerinde en sık bazal hücreli karsinom gözlenmektedir, bunu ikinci sırada yassı hücreli karsinom izlemektedir. Anahtar kelimeler: Göz kapağı, kitle, histopatoloji, iyi huylu, kötü huylu, tümör

Anahtar Kelimeler

• Göz kapağı, kitle, histopatoloji, iyi huylu, kötü huylu, tümör

Kaynakça

1. Kandemir NO, Barut F, Bektaş S, ve ark. Tumors and tumorlike
2. lesions of the eyelid and conjunctiva. Turk J Pathol
3. ;25:112-117.
4. Bagheri A, Tavakoli M, Kanaani A, et al. Eyelid masses: A
5. -year survey from a tertiary eye hospital in Tehran. Middle
6. East African J Ophthalmol 2013;20:187-192.
7. Actis AG, Actis G, De Sanctis U, et al. Eyelid benign and
8. malignant tumors: issues in classification, excision and reconstruction.

9. Minerva Chir 2013;68:11-25.
10. Gilchrist H, Lee G. Management of chalazia in general practice.
11. Aust Fam Physician. 2009 ;38:311-314.
12. Smith RJ, Kuo IC, Reviglio VE. Multiple apocrine hidrocystomas
13. of the eyelids. Orbit 2012;31:140-142.
14. Margo CE. Eyelid tumors: accuracy of clinical diagnosis.
15. Am J Ophthalmol. 1999 ;128:635-636.
16. Chang CH, Chang SM, Lai YH, et al. Eyelid tumors in southern
17. Taiwan: a 5-year survey from a medical university.
18. Kaohsiung J Med Sci 2003;19:549-554.
19. Obata H, Aoki Y, Kubota S, et al. Incidence of benign and
20. malignant lesions of eyelid and conjunctival tumors. Nippon
21. Ganka Gakkai Zasshi 2005;109:573-579.
22. Xu XL, Li B, Sun XL, et al. Eyelid neoplasms in the Beijing
23. Tongren Eye Centre between 1997 and 2006. Ophthalmic
24. Surg Lasers Imaging 2008;39:367-372.
25. Deprez M, Uffer S. Clinicopathological features of eyelid
26. skin tumors. A retrospective study of 5504 cases and review
27. of literature. Am J Dermatopathol 2009;31:256-262.
28. Erdoğan H, Demirci Y, Dursun A, ve ark. Göz kapağı kitlelerinin
29. histopatolojik sonuçları. Türkiye Klinikleri J Opthalmol.
30. ;22:75-80.
31. Hałoń A, Błazejewska M, Sabri H, Rabczyński J. Tumors
32. and tumor-like lesions of eyelids collected at Department
33. of Pathological Anatomy, Wroclaw Medical University, between
34. and 1999 Klin Oczna. 2005;107:475-478.
35. Uzun A, Gündüz K, Erden E, Heper OA. İyi huylu göz kapağı
36. tümörlerinde klinik ve histopatolojik tanı. Turk J Ophthalmol
37. ;42:43-46.
38. Nithithanaphat C, Ausayakhun S, Wiwatwongwana D, Mahanupab
39. P. Histopathological diagnosis of eyelid tumors
40. in Chiang Mai University Hospital. J Med Assoc Thai
41. ;97:1096-1099.
42. Kharrat W, Benzina Z, Khlif H, et al. J. Palpebral seborrheic
43. keratosis: a case study J Fr Ophtalmol 2004;27:1146-1149.
44. Kim JH, Bae HW, Lee KK, et al. Seborrheic keratosis
45. of the conjunctiva: a case report. Korean J Ophthalmol
46. ;23:306-308.
47. Jordan DR. Multiple epidermal inclusion cysts of the eyelid:
48. a simple technique for removal. Can J Ophthalmol
49. ;37:39-40.
50. Sarabi K, Khachemoune A. Hidrocystomas-a brief review.
51. MedGenMed 2006;8:57.
52. Rauso R, Tartaro G, Siniscalchi G, Colella G. Ecrine hidrocystoma:
53. a neoformation to be considered in differential
54. diagnoses of facial swellings. Minerva Stomatol
55. ;58:301-305.
56. Haik BG, Karcioglu ZA, Gordon RA, Pechous BP. Capillary
57. hemangioma (infantile periocular hemangioma) Surv
58. Ophthalmol 1994;38:399-426.
59. Ceisler E, Blei F. Ophthalmic issues in hemangiomas of
60. infancy. Lymphat Res Biol 2003;1:321-30.
61. Bergman R. The pathogenesis and clinical significance
62. of xanthelasma palpebrarum. J Am Acad Dermatol
63. ;30:236-242.
64. Park EJ, Youn SH, Cho EB, et al. Xanthelasma palpebrarum
65. treatment with a 1,450-nm-diode laser Dermatol Surg
66. ;37:791-796.
67. Perlman GS, Hornblass A. Basal cell carcinoma of the eyelids:
68. a review of patients treated by surgical excision. Ophthalmic
69. Surg 1976;7:23-27.
70. Hacker SM, Browder JF, Ramos-Caro FA Basal cell carcinoma.
71. Choosing the best method of treatment for a particular
72. lesion. Postgrad Med 1993;93:101-4, 106-8, 111.
73. Allali J, D’Hermies F, Renard G. Basal cell carcinomas of
74. the eyelids Ophthalmologica 2005;219:57-71.
75. Çömez TA, Akçay L, Doğan KÖ. Göz kapaklarının primer
76. kötü huylu tümörleri. Turk J Opthalmol 2012;42:412-417.
77. Soysal HG, Markoç F. Invasive squamous cell carcinoma
78. of the eyelids and periorbital region. Br J Ophthalmol
79. ;91:325-329.
80. Rene C. Oculoplastic aspects of ocular oncology. Eye
81. [Lond] 2013;27:199-207.
82. Cook BE Jr, Bartley GB. Epidemiologic characteristics and
83. clinical course of patients with malignant eyelid tumors in
84. an incidence cohort in Olmsted County, Minnesota. Opthalmology
85. ;106:746-750.
86. Donaldson MJ, Sullivan TJ, Whitehead KJ, Williamson
87. RM. Squamous cell carcinoma of the eyelids. Br J Ophthalmol
88. ;86:1161-1165.
89. Kwitko M, Boniuk M, Zimmerman LE. Eyelid tumors with
90. reference to lesions confused with squamous cell carcinoma.
91. Incidence and errors in diagnosis. Arch Ophthalmol
92. ;69:693-697.
93. Soysal HG, Albayrak A. Primary malignant tumors of eyelid.
94. Turk J Ophthalmol 2001;31:370-377.
95. Özkılıç E, Peksayar G. Epidemiolojic investigation of eyelid
96. tumors. Turk J Ophthalmol 2003;33:631-640