Metabolic Effectiveness of Laparoscopic Sleeve Gastrectomy in Morbid Obesity Treatment: Early and Mid-Term Results of a Single Center

Öz

Objective: The aim of this study is to reveal the efficacy of laparoscopic sleeve gastrectomy (LSG) in the preventable metabolic consequences of morbid obesity. We evaluated the weight loss according to body mass index (BMI), changes in comorbid diseases accompanying obesity in patients who underwent surgery in our clinic in the early and mid-period postoperatively, whether there was vitamin deficiency in the mid-term, and the complications associated with the surgery. Methods: In this study, a total of 50 patients aged 18-60 who underwent LSG intervention due to morbid obesity between January 1, 2010 and December 2019 by Dicle University School of Medicine, General Surgery Clinic, were retrospectively evaluated. Sociodemographic data of the patients, preoperative BMI, postoperative 3th month, 6th month and 1st year BMI values, preoperative and postoperative 12th month HgA1c levels were measured. Mortality and complication rates were evaluated. Results: The mean BMI of 50 patients at pre-LSG, postoperative 3rd month, 6th month and 1st year controls were respectively; 45.83±6.37, 37.63±5.88, 31.91±5.10 and 26.82±3.08kg/m2. Compared to before the intervention, the decrease in BMI was significant at the 3rd month, 6th month and 1st year controls (p <0.05). When paired comparisons were made, the BMI at the 1st year control was lower than the 6th and 3rd month (p<0.05). It was found that the preoperative HbA1c level of 6.55±1.37 decreased to 5.32±0.57 in the postoperative 12th month (p<0.05). Complication rate was determined as 2%. No mortality was observed during the follow-up. Conclusion: As a result of this study, it has been shown that LSG provides sufficient weight loss. In addition, LSG was found to be effective in achieving glycemic control and remission in Type 2 diabetes. In this study where mortality was not observed, LSG, which is a reliable method with acceptable operation time and postoperative complication rates, seems to be an effective solution in the surgical treatment of obesity. However, there is a need for more comprehensive randomized studies evaluating the long-term results of LSG.

Anahtar Kelimeler

• Complication
• Diabetes
• Laparoscopic Sleeve Gastrectomy

Kaynakça

1. 1. Cummings DE, Rubino F. Metabolic surgery for the treatment of type 2 diabetes in obese individuals. Diabetologia. 2018; 61: 257-64.
2. 2. Schauer PR, Bhatt DL, Kirwan JP, et al.; STAMPEDE Investigators. Bariatric Surgery versus Intensive Medical Therapy for Diabetes - 5-Year Outcomes. N Engl J Med. 2017; 376: 641-51.