Öz
Objective: To evaluate the histopathological results of cases who presented with an eyelid mass and underwent mass excision.Methods: The histopathological results of 107 cases, who underwent eyelid mass excision between May 2011 and March 2014 were retrospectively analyzed. Age and sex, mass localization, operative technique, and histopathological results were recorded.Results: Of 107 subjects included in the study, 61 were male and 46 were female, with a mean age of 49.44±19.81 years. The distribution of benign eyelid tumors were as follows: 37 (37.8%) squamous papillomas, 19 (19.4%) intradermal nevus, 9 (9.2%) seborrheic keratosis, 7 (7.1%) epidermal inclusion cyst, 6 (6.1%) inflammatory lesions, 5 (5.1%) suderiferous cysts, 5 (5.1%) capillary hemangiomas, 3 (3.1%) xanthelasma, 3 (3.1%) fibromas, 1 (1.0%) moll gland cyst, 1 (1.0%) chondroid syringoma, 1 (1.0%) dermoid cyst, and 1 (1.0%) actinic keratosis. Malignant eyelid tumors included 8 (88.9%) cases of basal cell carcinomas and 1 (11.1%) squamous cell carcinoma.Conclusion: In this study squamous papilloma was the most common benign eyelid tumor followed by intradermal nevus. Basal cell carcinoma was the most common malignant eyelid tumor followed by squamous cell carcinoma
Kaynakça
- Kandemir NO, Barut F, Bektaş S, ve ark. Tumors and tumorlike
- lesions of the eyelid and conjunctiva. Turk J Pathol
- ;25:112-117.
- Bagheri A, Tavakoli M, Kanaani A, et al. Eyelid masses: A
- -year survey from a tertiary eye hospital in Tehran. Middle
- East African J Ophthalmol 2013;20:187-192.
- Actis AG, Actis G, De Sanctis U, et al. Eyelid benign and
- malignant tumors: issues in classification, excision and reconstruction.
- Minerva Chir 2013;68:11-25.
- Gilchrist H, Lee G. Management of chalazia in general practice.
- Aust Fam Physician. 2009 ;38:311-314.
- Smith RJ, Kuo IC, Reviglio VE. Multiple apocrine hidrocystomas
- of the eyelids. Orbit 2012;31:140-142.
- Margo CE. Eyelid tumors: accuracy of clinical diagnosis.
- Am J Ophthalmol. 1999 ;128:635-636.
- Chang CH, Chang SM, Lai YH, et al. Eyelid tumors in southern
- Taiwan: a 5-year survey from a medical university.
- Kaohsiung J Med Sci 2003;19:549-554.
- Obata H, Aoki Y, Kubota S, et al. Incidence of benign and
- malignant lesions of eyelid and conjunctival tumors. Nippon
- Ganka Gakkai Zasshi 2005;109:573-579.
- Xu XL, Li B, Sun XL, et al. Eyelid neoplasms in the Beijing
- Tongren Eye Centre between 1997 and 2006. Ophthalmic
- Surg Lasers Imaging 2008;39:367-372.
- Deprez M, Uffer S. Clinicopathological features of eyelid
- skin tumors. A retrospective study of 5504 cases and review
- of literature. Am J Dermatopathol 2009;31:256-262.
- Erdoğan H, Demirci Y, Dursun A, ve ark. Göz kapağı kitlelerinin
- histopatolojik sonuçları. Türkiye Klinikleri J Opthalmol.
- ;22:75-80.
- Hałoń A, Błazejewska M, Sabri H, Rabczyński J. Tumors
- and tumor-like lesions of eyelids collected at Department
- of Pathological Anatomy, Wroclaw Medical University, between
- and 1999 Klin Oczna. 2005;107:475-478.
- Uzun A, Gündüz K, Erden E, Heper OA. İyi huylu göz kapağı
- tümörlerinde klinik ve histopatolojik tanı. Turk J Ophthalmol
- ;42:43-46.
- Nithithanaphat C, Ausayakhun S, Wiwatwongwana D, Mahanupab
- P. Histopathological diagnosis of eyelid tumors
- in Chiang Mai University Hospital. J Med Assoc Thai
- ;97:1096-1099.
- Kharrat W, Benzina Z, Khlif H, et al. J. Palpebral seborrheic
- keratosis: a case study J Fr Ophtalmol 2004;27:1146-1149.
- Kim JH, Bae HW, Lee KK, et al. Seborrheic keratosis
- of the conjunctiva: a case report. Korean J Ophthalmol
- ;23:306-308.
- Jordan DR. Multiple epidermal inclusion cysts of the eyelid:
- a simple technique for removal. Can J Ophthalmol
- ;37:39-40.
- Sarabi K, Khachemoune A. Hidrocystomas-a brief review.
- MedGenMed 2006;8:57.
- Rauso R, Tartaro G, Siniscalchi G, Colella G. Ecrine hidrocystoma:
- a neoformation to be considered in differential
- diagnoses of facial swellings. Minerva Stomatol
- ;58:301-305.
- Haik BG, Karcioglu ZA, Gordon RA, Pechous BP. Capillary
- hemangioma (infantile periocular hemangioma) Surv
- Ophthalmol 1994;38:399-426.
- Ceisler E, Blei F. Ophthalmic issues in hemangiomas of
- infancy. Lymphat Res Biol 2003;1:321-30.
- Bergman R. The pathogenesis and clinical significance
- of xanthelasma palpebrarum. J Am Acad Dermatol
- ;30:236-242.
- Park EJ, Youn SH, Cho EB, et al. Xanthelasma palpebrarum
- treatment with a 1,450-nm-diode laser Dermatol Surg
- ;37:791-796.
- Perlman GS, Hornblass A. Basal cell carcinoma of the eyelids:
- a review of patients treated by surgical excision. Ophthalmic
- Surg 1976;7:23-27.
- Hacker SM, Browder JF, Ramos-Caro FA Basal cell carcinoma.
- Choosing the best method of treatment for a particular
- lesion. Postgrad Med 1993;93:101-4, 106-8, 111.
- Allali J, D’Hermies F, Renard G. Basal cell carcinomas of
- the eyelids Ophthalmologica 2005;219:57-71.
- Çömez TA, Akçay L, Doğan KÖ. Göz kapaklarının primer
- kötü huylu tümörleri. Turk J Opthalmol 2012;42:412-417.
- Soysal HG, Markoç F. Invasive squamous cell carcinoma
- of the eyelids and periorbital region. Br J Ophthalmol
- ;91:325-329.
- Rene C. Oculoplastic aspects of ocular oncology. Eye
- [Lond] 2013;27:199-207.
- Cook BE Jr, Bartley GB. Epidemiologic characteristics and
- clinical course of patients with malignant eyelid tumors in
- an incidence cohort in Olmsted County, Minnesota. Opthalmology
- ;106:746-750.
- Donaldson MJ, Sullivan TJ, Whitehead KJ, Williamson
- RM. Squamous cell carcinoma of the eyelids. Br J Ophthalmol
- ;86:1161-1165.
- Kwitko M, Boniuk M, Zimmerman LE. Eyelid tumors with
- reference to lesions confused with squamous cell carcinoma.
- Incidence and errors in diagnosis. Arch Ophthalmol
- ;69:693-697.
- Soysal HG, Albayrak A. Primary malignant tumors of eyelid.
- Turk J Ophthalmol 2001;31:370-377.
- Özkılıç E, Peksayar G. Epidemiolojic investigation of eyelid
- tumors. Turk J Ophthalmol 2003;33:631-640
Öz
Amaç: Göz kapağında kitle nedeniyle başvuran ve kitle eksizyonu yapılan olguların histopatolojik sonuçlarını de- ğerlendirmek. Yöntemler: Mayıs 2011 ile Mart 2014 tarihleri arasında göz kapağı kitlesi eksizyonu yapılan 107 olgunun histopatolojik sonuçları retrospektif olarak değerlendirildi. Vakaların yaşı ve cinsiyeti, kitlenin lokalizasyonu, ameliyat tekniği ve histopatolojik tanıları kaydedildi. Bulgular: Çalışmaya dahil edilen 107 hastanın 61’i erkek, 46’sı kadın olup yaş ortalaması 49,44±19,81 yıl idi. İyi huylu göz kapağı tümörlerinin histopatolojik sonuçlarına göre dağılımı skuamöz papillom 37 olgu (%37,8), intradermal nevüs 19 olgu (%19,4), seboreik keratoz 9 olgu (%9,2), epidermal inklüzyon kisti 7 olgu (%7,1), inflamatuar lezyon 6 olgu (%6,1), suderiferöz kist 5 olgu (%5,1), kapiller hemanjiom 5 olgu (%5,1), ksantelezma 3 olgu (%3,1), fibrom 3 olgu (%3,1), moll gland kisti 1 olgu (%1,0), kondroid syringoma 1 olgu (%1,0), dermoid kist 1 olgu (%1,0), aktinik keratoz 1 olgu (%1,0) idi. Kötü huylu göz kapağı tümörlerinin histopatolojik sonuçlarına göre dağılımı bazal hücreli karsinom 8 olgu (%88,9), yassı hücreli karsinom 1 olgu (%11,1) idi. Sonuç: Çalışmamızda skuamöz papillom en sık görülen iyi huylu kapak tümörüdür ve bunu ikinci sırada intradermal nevüs izlemektedir. Kötü huylu kapak tümörlerinde en sık bazal hücreli karsinom gözlenmektedir, bunu ikinci sırada yassı hücreli karsinom izlemektedir. Anahtar kelimeler: Göz kapağı, kitle, histopatoloji, iyi huylu, kötü huylu, tümör
Anahtar Kelimeler
Kaynakça
- Kandemir NO, Barut F, Bektaş S, ve ark. Tumors and tumorlike
- lesions of the eyelid and conjunctiva. Turk J Pathol
- ;25:112-117.
- Bagheri A, Tavakoli M, Kanaani A, et al. Eyelid masses: A
- -year survey from a tertiary eye hospital in Tehran. Middle
- East African J Ophthalmol 2013;20:187-192.
- Actis AG, Actis G, De Sanctis U, et al. Eyelid benign and
- malignant tumors: issues in classification, excision and reconstruction.
- Minerva Chir 2013;68:11-25.
- Gilchrist H, Lee G. Management of chalazia in general practice.
- Aust Fam Physician. 2009 ;38:311-314.
- Smith RJ, Kuo IC, Reviglio VE. Multiple apocrine hidrocystomas
- of the eyelids. Orbit 2012;31:140-142.
- Margo CE. Eyelid tumors: accuracy of clinical diagnosis.
- Am J Ophthalmol. 1999 ;128:635-636.
- Chang CH, Chang SM, Lai YH, et al. Eyelid tumors in southern
- Taiwan: a 5-year survey from a medical university.
- Kaohsiung J Med Sci 2003;19:549-554.
- Obata H, Aoki Y, Kubota S, et al. Incidence of benign and
- malignant lesions of eyelid and conjunctival tumors. Nippon
- Ganka Gakkai Zasshi 2005;109:573-579.
- Xu XL, Li B, Sun XL, et al. Eyelid neoplasms in the Beijing
- Tongren Eye Centre between 1997 and 2006. Ophthalmic
- Surg Lasers Imaging 2008;39:367-372.
- Deprez M, Uffer S. Clinicopathological features of eyelid
- skin tumors. A retrospective study of 5504 cases and review
- of literature. Am J Dermatopathol 2009;31:256-262.
- Erdoğan H, Demirci Y, Dursun A, ve ark. Göz kapağı kitlelerinin
- histopatolojik sonuçları. Türkiye Klinikleri J Opthalmol.
- ;22:75-80.
- Hałoń A, Błazejewska M, Sabri H, Rabczyński J. Tumors
- and tumor-like lesions of eyelids collected at Department
- of Pathological Anatomy, Wroclaw Medical University, between
- and 1999 Klin Oczna. 2005;107:475-478.
- Uzun A, Gündüz K, Erden E, Heper OA. İyi huylu göz kapağı
- tümörlerinde klinik ve histopatolojik tanı. Turk J Ophthalmol
- ;42:43-46.
- Nithithanaphat C, Ausayakhun S, Wiwatwongwana D, Mahanupab
- P. Histopathological diagnosis of eyelid tumors
- in Chiang Mai University Hospital. J Med Assoc Thai
- ;97:1096-1099.
- Kharrat W, Benzina Z, Khlif H, et al. J. Palpebral seborrheic
- keratosis: a case study J Fr Ophtalmol 2004;27:1146-1149.
- Kim JH, Bae HW, Lee KK, et al. Seborrheic keratosis
- of the conjunctiva: a case report. Korean J Ophthalmol
- ;23:306-308.
- Jordan DR. Multiple epidermal inclusion cysts of the eyelid:
- a simple technique for removal. Can J Ophthalmol
- ;37:39-40.
- Sarabi K, Khachemoune A. Hidrocystomas-a brief review.
- MedGenMed 2006;8:57.
- Rauso R, Tartaro G, Siniscalchi G, Colella G. Ecrine hidrocystoma:
- a neoformation to be considered in differential
- diagnoses of facial swellings. Minerva Stomatol
- ;58:301-305.
- Haik BG, Karcioglu ZA, Gordon RA, Pechous BP. Capillary
- hemangioma (infantile periocular hemangioma) Surv
- Ophthalmol 1994;38:399-426.
- Ceisler E, Blei F. Ophthalmic issues in hemangiomas of
- infancy. Lymphat Res Biol 2003;1:321-30.
- Bergman R. The pathogenesis and clinical significance
- of xanthelasma palpebrarum. J Am Acad Dermatol
- ;30:236-242.
- Park EJ, Youn SH, Cho EB, et al. Xanthelasma palpebrarum
- treatment with a 1,450-nm-diode laser Dermatol Surg
- ;37:791-796.
- Perlman GS, Hornblass A. Basal cell carcinoma of the eyelids:
- a review of patients treated by surgical excision. Ophthalmic
- Surg 1976;7:23-27.
- Hacker SM, Browder JF, Ramos-Caro FA Basal cell carcinoma.
- Choosing the best method of treatment for a particular
- lesion. Postgrad Med 1993;93:101-4, 106-8, 111.
- Allali J, D’Hermies F, Renard G. Basal cell carcinomas of
- the eyelids Ophthalmologica 2005;219:57-71.
- Çömez TA, Akçay L, Doğan KÖ. Göz kapaklarının primer
- kötü huylu tümörleri. Turk J Opthalmol 2012;42:412-417.
- Soysal HG, Markoç F. Invasive squamous cell carcinoma
- of the eyelids and periorbital region. Br J Ophthalmol
- ;91:325-329.
- Rene C. Oculoplastic aspects of ocular oncology. Eye
- [Lond] 2013;27:199-207.
- Cook BE Jr, Bartley GB. Epidemiologic characteristics and
- clinical course of patients with malignant eyelid tumors in
- an incidence cohort in Olmsted County, Minnesota. Opthalmology
- ;106:746-750.
- Donaldson MJ, Sullivan TJ, Whitehead KJ, Williamson
- RM. Squamous cell carcinoma of the eyelids. Br J Ophthalmol
- ;86:1161-1165.
- Kwitko M, Boniuk M, Zimmerman LE. Eyelid tumors with
- reference to lesions confused with squamous cell carcinoma.
- Incidence and errors in diagnosis. Arch Ophthalmol
- ;69:693-697.
- Soysal HG, Albayrak A. Primary malignant tumors of eyelid.
- Turk J Ophthalmol 2001;31:370-377.
- Özkılıç E, Peksayar G. Epidemiolojic investigation of eyelid
- tumors. Turk J Ophthalmol 2003;33:631-640
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Araştırma Yazıları |
| Yazarlar | |
| Yayımlanma Tarihi | 9 Mayıs 2015 |
| Gönderilme Tarihi | 9 Mayıs 2015 |
| Yayımlandığı Sayı | Yıl 2015 Cilt: 42 Sayı: 1 |