Araştırma Makalesi

The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio

Cilt: 47 Sayı: 1 17 Mart 2020
  • Nizamettin Selçuk Yelgeç *
  • Mehmet Baran Karataş
  • Can Yücel Karabay
  • Yiğit Çanga
  • Ali Nazmi Çalık
  • Barış Şimşek
  • Özge Güzelburç
  • Ayşe Emre
PDF İndir

The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio

Öz

Objective: Transcatheter aortic valve replacement (TAVR) is a less invasive alternative to open-heart surgery for patients with severe symptomatic aortic stenosis who has a high risk for surgery. Acute kidney injury (AKI) is not a rare complication after TAVR and has been associated with poorer outcomes and survival. This study aims to analyze the relation between serum Neutrophil-lymphocyte ratio (NLR) and AKI in Post-TAVR patients. Methods: 148 patients who have been performed TAVR at our institution between 2010 and 2018, analyzed retrospectively. We divided the patients into two groups. Group 1 (n=116): The patients who did not develop AKI after TAVR procedure (control group) and Group 2 (n=32): The patients who developed AKI after TAVR. The independent relation between possible independent predictors of AKI in post-TAVI patients was analyzed by regression analysis. Results: 32 patients (22%) suffered from AKI after TAVR during hospitalization. NLR was significantly associated with the development of AKI (3.22 ±0.62 vs. 2.42 ± 0.45, p<0.01). In multivariate regression analysis, NLR (OR: 1.79, p=0,01), diabetes mellitus (OR: 1.41, p=0,01), and preprocedural creatinine levels (OR: 1.86, p=0,01) were found to be independently correlated with the development of AKI after TAVR. Conclusion: This study suggests that High NLR was independently associated with AKI in post-TAVR patients. High values of NLR may indicate a poor prognosis.

Anahtar Kelimeler

Kaynakça

  1. 1. Lindman BR, Clavel M-A, Mathieu P, et al. Calcific aortic stenosis. Nat Rev Dis Prim. 2016; 2: 16006.
  2. 2. Eveborn GW, Schirmer H, Heggelund G, et al. The evolving epidemiology of valvular aortic stenosis. theTromsø Study. Heart. 2013 Mar 15; 99: 396–400.
  3. 3. Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am CollCardiol. 2014 Jun 10; 63: e57-185.
  4. 4. Bagur R, Webb JG, Nietlispach F, et al. Acute kidney injury following transcatheter aortic valve implantation: predictive factors, prognostic value, and comparison with surgical aortic valve replacement. Eur Heart J. 2010 Apr 1; 31: 865–74.
  5. 5. Najjar M, Salna M, George I. Acute kidney injury after aortic valve replacement: Incidence, risk factors and outcomes. Expert Review of Cardiovascular Therapy. 2015.
  6. 6. Papa A, Emdin M, Passino C, et al. Predictive value of elevated neutrophil-lymphocyte ratio on cardiac mortality in patients with stable coronary artery disease. ClinChimActa. 2008 Sep; 395: 27–31.
  7. 7. Park B-J, Shim J-Y, Lee H-R, et al. Relationship of neutrophil-lymphocyte ratio with arterial stiffness and coronary calcium score. ClinChimActa. 2011 May 12; 412: 925–9.
  8. 8. Zazula AD, Précoma-Neto D, Gomes AM, et al. An assessment of neutrophils/lymphocytes ratio in patients suspected of acute coronary syndrome. Arq Bras Cardiol. 2008 Jan; 90: 31–6.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yazarlar

Nizamettin Selçuk Yelgeç * Bu kişi benim
Türkiye

Mehmet Baran Karataş Bu kişi benim
Türkiye

Can Yücel Karabay Bu kişi benim
Türkiye

Yiğit Çanga Bu kişi benim
Türkiye

Ali Nazmi Çalık Bu kişi benim
Türkiye

Barış Şimşek Bu kişi benim
Türkiye

Özge Güzelburç Bu kişi benim
Türkiye

Ayşe Emre Bu kişi benim
Türkiye

Yayımlanma Tarihi

17 Mart 2020

Gönderilme Tarihi

2 Ekim 2019

Kabul Tarihi

11 Şubat 2020

Yayımlandığı Sayı

Yıl 2020 Cilt: 47 Sayı: 1

Kaynak Göster

APA
Yelgeç, N. S., Karataş, M. B., Karabay, C. Y., Çanga, Y., Çalık, A. N., Şimşek, B., Güzelburç, Ö., & Emre, A. (2020). The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio. Dicle Medical Journal, 47(1), 1-9. https://doi.org/10.5798/dicletip.705532
AMA
1.Yelgeç NS, Karataş MB, Karabay CY, vd. The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio. diclemedj. 2020;47(1):1-9. doi:10.5798/dicletip.705532
Chicago
Yelgeç, Nizamettin Selçuk, Mehmet Baran Karataş, Can Yücel Karabay, vd. 2020. “The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio”. Dicle Medical Journal 47 (1): 1-9. https://doi.org/10.5798/dicletip.705532.
EndNote
Yelgeç NS, Karataş MB, Karabay CY, Çanga Y, Çalık AN, Şimşek B, Güzelburç Ö, Emre A (01 Mart 2020) The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio. Dicle Medical Journal 47 1 1–9.
IEEE
[1]N. S. Yelgeç vd., “The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio”, diclemedj, c. 47, sy 1, ss. 1–9, Mar. 2020, doi: 10.5798/dicletip.705532.
ISNAD
Yelgeç, Nizamettin Selçuk - Karataş, Mehmet Baran - Karabay, Can Yücel - Çanga, Yiğit - Çalık, Ali Nazmi - Şimşek, Barış - Güzelburç, Özge - Emre, Ayşe. “The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio”. Dicle Medical Journal 47/1 (01 Mart 2020): 1-9. https://doi.org/10.5798/dicletip.705532.
JAMA
1.Yelgeç NS, Karataş MB, Karabay CY, Çanga Y, Çalık AN, Şimşek B, Güzelburç Ö, Emre A. The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio. diclemedj. 2020;47:1–9.
MLA
Yelgeç, Nizamettin Selçuk, vd. “The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio”. Dicle Medical Journal, c. 47, sy 1, Mart 2020, ss. 1-9, doi:10.5798/dicletip.705532.
Vancouver
1.Nizamettin Selçuk Yelgeç, Mehmet Baran Karataş, Can Yücel Karabay, Yiğit Çanga, Ali Nazmi Çalık, Barış Şimşek, Özge Güzelburç, Ayşe Emre. The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio. diclemedj. 01 Mart 2020;47(1):1-9. doi:10.5798/dicletip.705532

Cited By