Objective: Transcatheter aortic valve replacement (TAVR) is a less invasive alternative to open-heart surgery for patients with severe symptomatic aortic stenosis who has a high risk for surgery. Acute kidney injury (AKI) is not a rare complication after TAVR and has been associated with poorer outcomes and survival. This study aims to analyze the relation between serum Neutrophil-lymphocyte ratio (NLR) and AKI in Post-TAVR patients.
Methods: 148 patients who have been performed TAVR at our institution between 2010 and 2018, analyzed retrospectively. We divided the patients into two groups. Group 1 (n=116): The patients who did not develop AKI after TAVR procedure (control group) and Group 2 (n=32): The patients who developed AKI after TAVR. The independent relation between possible independent predictors of AKI in post-TAVI patients was analyzed by regression analysis.
Results: 32 patients (22%) suffered from AKI after TAVR during hospitalization. NLR was significantly associated with the development of AKI (3.22 ±0.62 vs. 2.42 ± 0.45, p<0.01). In multivariate regression analysis, NLR (OR: 1.79, p=0,01), diabetes mellitus (OR: 1.41, p=0,01), and preprocedural creatinine levels (OR: 1.86, p=0,01) were found to be independently correlated with the development of AKI after TAVR.
Conclusion: This study suggests that High NLR was independently associated with AKI in post-TAVR patients. High values of NLR may indicate a poor prognosis.
Neutrophil to lymphocyte ratio Transcatheter aortic valve implantation
Birincil Dil | İngilizce |
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Konular | Sağlık Kurumları Yönetimi |
Bölüm | Original Articles |
Yazarlar | |
Yayımlanma Tarihi | 17 Mart 2020 |
Gönderilme Tarihi | 2 Ekim 2019 |
Yayımlandığı Sayı | Yıl 2020 Cilt: 47 Sayı: 1 |