Araştırma Makalesi

Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients

Cilt: 47 Sayı: 1 17 Mart 2020
  • Alper Sarı
  • Memnune Sena Ulu
  • Sinan Kazan
  • Onur Tunca
  • Elif Dizen Kazan
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Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients

Öz

Objective: Chronic kidney disease (CKD) is an inflammatory process. Serum proinflammatory cytokines are known to be ten times higher in patients with CKD when compared to normal population. Monocyte/High density lipoprotein (HDL) cholesterol ratio (MHR) have been shown to be a new marker of inflammation and claimed that, it may be used to predict cardiovascular events in patients with CKD. This cross-sectional study aimed to compare monocyte / HDL cholesterol ratio in patients treated with hemodialysis and peritoneal dialysis. Methods: Files of patients who have been followed up with end stage renal disease (ESRD) and have peritoneal dialysis or hemodialysis therapy in Nephrology Clinic of our hospital have been retrospectively examined. Patients were divided into two groups regarding renal replacement treatment type. Monocyte / HDL cholesterol ratio was compared between groups. IBM SPSS Statistics 22.0 (IBM Corp., NY, USA) packaged software and appropriate statistical methods were used to analyse data. Results: Monocyte / HDL cholesterol ratio was significantly higher in patients treated with hemodialysis (p= 0.028). HDL cholesterol levels were significantly higher in peritoneal dialysis group (p= 0.046). Total cholesterol, LDL cholesterol, triglyceride and VLDL cholesterol have been ascertained to be similar in both patient groups (p> 0.05). The high sensitivity CRP and sedimentation levels have been detected to be similar within the groups (p> 0.05). Conclusion: This is the first study evaluating the monocyte/HDL cholesterol ratio among renal replacement therapy modalities in our literature review. In this study, it has been shown that; monocyte/HDL cholesterol ratio were statistically higher in patients having hemodialysis than in the ones followed up with peritoneal dialysis. According to these results, it may be considered that; peritoneal dialysis may be associated with less systemic inflammation than hemodialysis.

Anahtar Kelimeler

Kaynakça

  1. 1. National Kidney Foundation. K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Clasification and Stratification. Am J Kidney Dis. 2002; Vol. 39: 1-266
  2. 2. Zyga S, Christopoulou G, Malliarou M. Malnutrition-inflammation-atherosclerosis syndrome in patients with end-stage renal disease. J Ren Care. 2011; 37: 12–5.
  3. 3. Tonbul HZ, Demir M, Altintepe L, et al. Malnutrition-Inflammation-Atherosclerosis syndrome componentsin hemodialysis and peritoneal dialysis patients. 2006; 24: 287-94.
  4. 4. Rao P, Reddy GC, Kanagasabapathy AS. Malnutrition-inflammation-atherosclerosis syndrome in Chronic Kidney disease. Indian J ClinBiochem. 2008; 23: 209–17.
  5. 5. Stenvinkel P. Inflammation in end-stage renal failure: could it be treated? Nephrol Dial Transpl. 2002; 17 Suppl 8: 33–8; discussion 40.
  6. 6. Daugirdas JT, Blake P, Ing TS, et al. Handbook of Dialysis, Fourth Edition. Dial Transplant. 2007; 36: 322.
  7. 7. Ancuta P, Wang J, Gabuzda D. CD16+ monocytes produce IL-6, CCL2, and matrix metalloproteinase-9 upon interaction with CX3CL1-expressing endothelial cells. J Leukoc Biol. 2006; 80: 1156–64.
  8. 8. Hessler JR, Robertson AL, Chisolm GM. LDL-induced cytotoxicity and its inhibition by HDL in human vascular smooth muscle and endothelial cells in culture. Atherosclerosis. 1979; 32: 213–29.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yazarlar

Alper Sarı Bu kişi benim
Türkiye

Memnune Sena Ulu Bu kişi benim
Türkiye

Sinan Kazan Bu kişi benim
Türkiye

Onur Tunca Bu kişi benim
Türkiye

Elif Dizen Kazan Bu kişi benim
Türkiye

Yayımlanma Tarihi

17 Mart 2020

Gönderilme Tarihi

4 Şubat 2020

Kabul Tarihi

5 Mart 2020

Yayımlandığı Sayı

Yıl 2020 Cilt: 47 Sayı: 1

Kaynak Göster

APA
Sarı, A., Ulu, M. S., Kazan, S., Tunca, O., & Kazan, E. D. (2020). Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients. Dicle Medical Journal, 47(1), 139-137. https://doi.org/10.5798/dicletip.706097
AMA
1.Sarı A, Ulu MS, Kazan S, Tunca O, Kazan ED. Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients. diclemedj. 2020;47(1):139-137. doi:10.5798/dicletip.706097
Chicago
Sarı, Alper, Memnune Sena Ulu, Sinan Kazan, Onur Tunca, ve Elif Dizen Kazan. 2020. “Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients”. Dicle Medical Journal 47 (1): 139-37. https://doi.org/10.5798/dicletip.706097.
EndNote
Sarı A, Ulu MS, Kazan S, Tunca O, Kazan ED (01 Mart 2020) Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients. Dicle Medical Journal 47 1 139–137.
IEEE
[1]A. Sarı, M. S. Ulu, S. Kazan, O. Tunca, ve E. D. Kazan, “Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients”, diclemedj, c. 47, sy 1, ss. 139–137, Mar. 2020, doi: 10.5798/dicletip.706097.
ISNAD
Sarı, Alper - Ulu, Memnune Sena - Kazan, Sinan - Tunca, Onur - Kazan, Elif Dizen. “Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients”. Dicle Medical Journal 47/1 (01 Mart 2020): 139-137. https://doi.org/10.5798/dicletip.706097.
JAMA
1.Sarı A, Ulu MS, Kazan S, Tunca O, Kazan ED. Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients. diclemedj. 2020;47:139–137.
MLA
Sarı, Alper, vd. “Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients”. Dicle Medical Journal, c. 47, sy 1, Mart 2020, ss. 139-7, doi:10.5798/dicletip.706097.
Vancouver
1.Alper Sarı, Memnune Sena Ulu, Sinan Kazan, Onur Tunca, Elif Dizen Kazan. Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients. diclemedj. 01 Mart 2020;47(1):139-7. doi:10.5798/dicletip.706097

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