Klinik Araştırma
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New Bone Formation during Horizontal Alveolar Distraction Osteogenesis

Yıl 2020, Cilt: 6 Sayı: 3, 1 - 7, 31.12.2020

Öz

Distraction osteogenesis is a method of generating new bone following an osteotomy and gradual distraction. It presents an alternative procedure for the augmentation of atrophic alveolar bone before inserting dental implants. The present study evaluates the bone formation during horizontal alveolar distraction osteogenesis used to expand the edentulous narrow ridges in the posterior region of the mandible. A total of 7 patients with an edentulous narrow alveolar bone ridge in the posterior mandibular region were included in the present study, horizontal alveolar distraction osteogenesis technique was applied to increase the width of alveolar bone. After 4 months of surgery at the time of implants insertion, 7 biopsies (one from each patient) of the regenerative zone were taken with trephine burr for histological analysis.The histological study showed that the interzone was bounded on either side by areas of bone formation that originated from the host bone margins. The newly formed bone consisted of woven bone reinforced by lamellar bone with the presence of bone marrow spaces in the newly formed bone. The activity of the osteoblast differentiation was good to excellent in 6 samples, and poor with intense vascular congestion and inflammation in one sample.Horizontal alveolar distraction osteogenesis successfully inducing the bone formation, and is a reliable technique to expand the narrow alveolar bone.

Kaynakça

  • 1- Schropp L, Wenzel A, Kostopoulos L, Karring T. Bone healing and soft tissue contour changes following single-tooth extraction: a clinical and radiographic 12-month prospective study. Int J Period Restor Dent 2003; 23: 313-23.
  • 2- Pietrokovski J, Massler M. Alveolar ridge resorption after tooth extraction. J Prosth Dent 8. 1967; 17: 21-7.
  • 3- Simion M, Baldoni M, Rossi P, Zaffe D. A comparative study of the effectiveness of e-PTFE 9. membranes with and without early exposure during the healing period. Int J Period Restor Dent 1994; 14: 166-80.
  • 4- Jahangiri L, Devlin H, Ting K, Nishimura I. Current perspectives in residual ridge remodeling and its clinical implications: a review. J Prosthet Dent. 1998; 80(2): 224-37.
  • 5- Johnson K. A study of the dimensional changes occurring in the maxilla following tooth extraction. Aust Dent J 1969; 14(4): 241-4.
  • 6- Lekovic V, Camargo PM, Klokkevold PR, et al. Preservation of alveolar bone in extraction sockets using bioabsorbable membranes. J Periodontol 1998; 69(9): 1044-9. 7- Lekovic, V., Kenney, E. B., Weinlaender, et al. A bone regenerative approach to alveolar ridge maintenance following tooth extraction. Report of 10 cases. Journal of Periodontology 1997; 68: 563–570.
  • 8- Arau´jo, M. G. & Lindhe, J. (2005) Dimensional ridge alterations following tooth extraction. An experimental study in the dog. Journal of Clinical Periodontology 2005; 32: 212–218.
  • 9- Pinho, M. N., Roriz, V. L., Novaes, et al. Titanium membranes in prevention of alveolar collapse after tooth extraction. Implant Dentistry 2006; 15: 53 61.
  • 10- Buser D, Martin W, Belser UC. Optimizing esthetics for implant restorations in the anterior maxilla: Anatomic and surgical considerations. Int J Oral Maxillofac Implants 2004; 19(Suppl.): 43-61.
  • 11- Klein, Marc O, Schiegnitz, Eik; Al-Nawas, et al. Systematic review on success of narrow-diameter dental implants. Int J Oral & Maxillofac Implants 2014; 29: 43–54.
  • 12- Chiapasco M, Casentini P, Zaniboni M. Bone augmentation procedures in implant dentistry. Int J Oral & Maxillofac Implants. 2009; 24 Suppl: 237–259.
  • 13- Codivilla A. On the means of lengthening, in the lower limbs, the muscles and tissues which are shortened through deformity. J Bone Joint Surg Am 1905; 2: 353-369.
  • 14- Amir LR · Everts V· Bronckers A. Bone regeneration during distraction osteogenesis. Odontology 2009; 97:63–75.
  • 15- Sumra N, Kulshrestha R. Distraction Osteogenesis in Implantology for Ridge Augmentation - A Systematic Review. Dent Implants Dentures 2017; 2: 119.
  • 16- Chin M, Toth BA. Distraction osteogenesis in maxillofacial surgery using internal devices: Review of five cases. J Oral Maxillofac Surg. 1996; 54(1): 45–53.
  • 17- Karp NS, McCarthy JG, Schreiber JS, et al. Membranous bone lengthening: a serial histological study. Ann Plast Surg 1992; 29(1): 2-7
  • 18- Takahashi T. Use of horizontal alveolar distraction osteogenesis for implant placement in a narrow alveolar ridge: A case report. Int J Oral Maxillofac Surg. 2004; 19(2): 291–294.
  • 19- Cope JB, Samchukov ML, Cherkashin AM Mandibular distraction osteogenesis: A historic perspective and future directions. Am J Orthod Dentofacial Orthop 1999; 115: 448-460.
  • 20- Ilizarov, G.A. Basic principles of transosseous compression and distraction osteosynthesis. Orthopedics Traumatology Protez 1975; 10: 7–155.
  • 21- McCarthy JG, Schreiber J, Karp N, et al: Lengthening the human mandible by gradual distraction. Plast Reconstr Surg 1992; 89(1): 1-8.
  • 22- Aparicio C, Jensen OT: Alveolar distraction to gain width, in Jensen OT (ed): Alveolar Distraction Osteogenesis. Chicago, IL, Quintessence, 2002, pp 133-148.
  • 23- Ilizarov GA. Clinical application of the tension-stress effect for limb lengthening. Clin Orthop 1990; 250: 8–26
  • 24- AI-Aql Z.S, Alag A.S, Graves D.T, Gerstenfeld L.C, Einhorn T.A. Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis. J Dent Res. 2008; 87(2): 107–118.
  • 25- Compton J, Fragomen A, Rozbruch R. Skeletal repair in distraction osteogenesis: Mechanisms and enhancements. JBJS REVIEWS 2015; 3(8): e2.
  • 26- Pérez-Sayáns M, Martínez-Martín JM, Chamorro-Petronacci C, Gallas- Torreira M, Marichalar-Mendía X, García- García A. 20 years of alveolar distraction: A systematic review of the literature. Med Oral Patol Oral Cir Bucal. 2018 Nov 1; 23(6): e742-e751.
  • 27- Saulacic N, Iizuka T, Martin MS, Garcia AG. Alveolar distraction osteogenesis: a systematic review. Int J Oral Maxillofac Surg. 2008; 37: 1-7.
  • 28- Cope JB, Samchukov ML. Regenerate bone formation and remodeling during mandibular osteodistraction. Angle Orthod 2000; 70: 99–111.
  • 29- Li G, Simpson AH, Kenwright J, Triffitt JT. Assessment of cell proliferation in regenerating bone during distraction osteogenesis at different distraction rates. J Orthop Res 1997; 15: 765–72.
  • 30- Rowe NM, Mehrara BJ, Luchs JS, Dudziak ME, Steinbrech DS, Illei PB, et al. Angiogenesis during mandibular distraction osteogenesis. Ann Plast Surg 1999; 42: 470–5.
  • 31- Choi IH, Chung CY, Cho TJ, Yoo WJ. Angiogenesis and mineralization during distraction osteogenesis. J Korean Med Sci 2002; 17: 435–47.
  • 32- Gantous A, Phillips JH, Catton P, Holmberg D Distraction osteogenesis in the irradiated canine mandible. Plast Reconstr Surg 1994; 93: 164-168.
  • 33- Amir, L.R., Becking, A.G., Jovanovic, A., Perdijk, F.B.T., Everts, V. & Bronckers, A.L.J.J. Vertical distraction osteogenesis in the human mandible: a prospective morphometric study. Clinical Oral Implants Research 2006; 17: 417–425.
  • 34- Baum R and Gravallese E.M. Impact of Inflammation on the Osteoblast in Rheumatic Diseases. Curr Osteoporos Rep. 2014 March ; 12(1): 9–16.
  • 35- Consolo, U., Bertoldi, C., Zaffe, D. Clinical evaluation, radiologic and histologic analysis in mandibular alveolar distraction procedures. Preliminary study. Minerva Stomatologica 2000; 49: 475–484.
  • 36- Zaffe, D., Bertoldi, C., Palumbo, C., Consolo, U. Morphofunctional and clinical study on mandibular alveolar distraction osteogenesis. Clinical Oral Implants Research 2002; 13: 550–557.
  • 37- Chiapasco M, Lang NP, Bosshardt DD. Quality and quantity of bone following alveolar distraction osteogenesis in the human mandible. Clin.Oral Impl. Res. 2006; 17: 394–402
  • 38- Türker N, Basa S, Vural G. Evaluation of osseous regeneration in alveolar distraction osteogenesis with histological and radiological aspects, J Oral Maxillofac Surg. 2007 Apr; 65(4): 608-614.

Yatay Alveoler Distraksiyon Osteogenezi Tekniğinde Yeni Kemik Oluşumu

Yıl 2020, Cilt: 6 Sayı: 3, 1 - 7, 31.12.2020

Öz

Distraksiyon osteogenezi, bir osteotomi ve aşamalı traksiyon sonrası yeni kemik üretme yöntemidir. Dental implantları yerleştirmeden önce atrofik alveoler kemiğin büyütülmesi için alternatif bir teknik sunar. Bu çalışmada, mandibulanın posterior bölgesindeki dişsiz dar sırtları genişletmek için kullanılan yatay alveolar, distraksiyon osteogenezi sırasında kemik oluşumunu değerlendirir.Posterior mandibular bölgesinde, dişsiz ve dar alveolar kemik sırtına sahip toplam 7 hasta çalışmaya dahil edildi. Alveolar kemiğin genişliğini arttırmak için yatay alveoler distraksiyon osteogenez tekniği uygulandı. İmplantların yerleştirildiği ameliyattan 4 ay sonra, Rejeneratif bölgenin biyopsisi (her hastadan bir tane) histolojik analiz için trefin burr ile alındı.Histolojik çalışma, interzonun her iki tarafından kemik oluşumu ile sınırlandığını (kemik olusumu konak kemik sınırlarından kaynaklanır) göstermiştir. Yeni oluşan kemik, lamel kemiği ile güçlendirilmiş dokuma kemikten oluşuyordu ve yeni oluşan kemikte kemik iliği boşlukları tespit edildi. 6 biyopside osteoblast farklılaşmasının etkinliği iyi ila mükemmel arasındaydı, 1 biyopside ise osteoblast farklılaşmasının etkinligi zayif ayrica yoğun vasküler konjesyon ve inflamasyon vardi. Yatay alveoler distraksiyon osteogenezi, kemik oluşumunu başarılı bir şekilde indükler ve dar alveolar kemiği genişletmek için güvenilir bir tekniktir.

Kaynakça

  • 1- Schropp L, Wenzel A, Kostopoulos L, Karring T. Bone healing and soft tissue contour changes following single-tooth extraction: a clinical and radiographic 12-month prospective study. Int J Period Restor Dent 2003; 23: 313-23.
  • 2- Pietrokovski J, Massler M. Alveolar ridge resorption after tooth extraction. J Prosth Dent 8. 1967; 17: 21-7.
  • 3- Simion M, Baldoni M, Rossi P, Zaffe D. A comparative study of the effectiveness of e-PTFE 9. membranes with and without early exposure during the healing period. Int J Period Restor Dent 1994; 14: 166-80.
  • 4- Jahangiri L, Devlin H, Ting K, Nishimura I. Current perspectives in residual ridge remodeling and its clinical implications: a review. J Prosthet Dent. 1998; 80(2): 224-37.
  • 5- Johnson K. A study of the dimensional changes occurring in the maxilla following tooth extraction. Aust Dent J 1969; 14(4): 241-4.
  • 6- Lekovic V, Camargo PM, Klokkevold PR, et al. Preservation of alveolar bone in extraction sockets using bioabsorbable membranes. J Periodontol 1998; 69(9): 1044-9. 7- Lekovic, V., Kenney, E. B., Weinlaender, et al. A bone regenerative approach to alveolar ridge maintenance following tooth extraction. Report of 10 cases. Journal of Periodontology 1997; 68: 563–570.
  • 8- Arau´jo, M. G. & Lindhe, J. (2005) Dimensional ridge alterations following tooth extraction. An experimental study in the dog. Journal of Clinical Periodontology 2005; 32: 212–218.
  • 9- Pinho, M. N., Roriz, V. L., Novaes, et al. Titanium membranes in prevention of alveolar collapse after tooth extraction. Implant Dentistry 2006; 15: 53 61.
  • 10- Buser D, Martin W, Belser UC. Optimizing esthetics for implant restorations in the anterior maxilla: Anatomic and surgical considerations. Int J Oral Maxillofac Implants 2004; 19(Suppl.): 43-61.
  • 11- Klein, Marc O, Schiegnitz, Eik; Al-Nawas, et al. Systematic review on success of narrow-diameter dental implants. Int J Oral & Maxillofac Implants 2014; 29: 43–54.
  • 12- Chiapasco M, Casentini P, Zaniboni M. Bone augmentation procedures in implant dentistry. Int J Oral & Maxillofac Implants. 2009; 24 Suppl: 237–259.
  • 13- Codivilla A. On the means of lengthening, in the lower limbs, the muscles and tissues which are shortened through deformity. J Bone Joint Surg Am 1905; 2: 353-369.
  • 14- Amir LR · Everts V· Bronckers A. Bone regeneration during distraction osteogenesis. Odontology 2009; 97:63–75.
  • 15- Sumra N, Kulshrestha R. Distraction Osteogenesis in Implantology for Ridge Augmentation - A Systematic Review. Dent Implants Dentures 2017; 2: 119.
  • 16- Chin M, Toth BA. Distraction osteogenesis in maxillofacial surgery using internal devices: Review of five cases. J Oral Maxillofac Surg. 1996; 54(1): 45–53.
  • 17- Karp NS, McCarthy JG, Schreiber JS, et al. Membranous bone lengthening: a serial histological study. Ann Plast Surg 1992; 29(1): 2-7
  • 18- Takahashi T. Use of horizontal alveolar distraction osteogenesis for implant placement in a narrow alveolar ridge: A case report. Int J Oral Maxillofac Surg. 2004; 19(2): 291–294.
  • 19- Cope JB, Samchukov ML, Cherkashin AM Mandibular distraction osteogenesis: A historic perspective and future directions. Am J Orthod Dentofacial Orthop 1999; 115: 448-460.
  • 20- Ilizarov, G.A. Basic principles of transosseous compression and distraction osteosynthesis. Orthopedics Traumatology Protez 1975; 10: 7–155.
  • 21- McCarthy JG, Schreiber J, Karp N, et al: Lengthening the human mandible by gradual distraction. Plast Reconstr Surg 1992; 89(1): 1-8.
  • 22- Aparicio C, Jensen OT: Alveolar distraction to gain width, in Jensen OT (ed): Alveolar Distraction Osteogenesis. Chicago, IL, Quintessence, 2002, pp 133-148.
  • 23- Ilizarov GA. Clinical application of the tension-stress effect for limb lengthening. Clin Orthop 1990; 250: 8–26
  • 24- AI-Aql Z.S, Alag A.S, Graves D.T, Gerstenfeld L.C, Einhorn T.A. Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis. J Dent Res. 2008; 87(2): 107–118.
  • 25- Compton J, Fragomen A, Rozbruch R. Skeletal repair in distraction osteogenesis: Mechanisms and enhancements. JBJS REVIEWS 2015; 3(8): e2.
  • 26- Pérez-Sayáns M, Martínez-Martín JM, Chamorro-Petronacci C, Gallas- Torreira M, Marichalar-Mendía X, García- García A. 20 years of alveolar distraction: A systematic review of the literature. Med Oral Patol Oral Cir Bucal. 2018 Nov 1; 23(6): e742-e751.
  • 27- Saulacic N, Iizuka T, Martin MS, Garcia AG. Alveolar distraction osteogenesis: a systematic review. Int J Oral Maxillofac Surg. 2008; 37: 1-7.
  • 28- Cope JB, Samchukov ML. Regenerate bone formation and remodeling during mandibular osteodistraction. Angle Orthod 2000; 70: 99–111.
  • 29- Li G, Simpson AH, Kenwright J, Triffitt JT. Assessment of cell proliferation in regenerating bone during distraction osteogenesis at different distraction rates. J Orthop Res 1997; 15: 765–72.
  • 30- Rowe NM, Mehrara BJ, Luchs JS, Dudziak ME, Steinbrech DS, Illei PB, et al. Angiogenesis during mandibular distraction osteogenesis. Ann Plast Surg 1999; 42: 470–5.
  • 31- Choi IH, Chung CY, Cho TJ, Yoo WJ. Angiogenesis and mineralization during distraction osteogenesis. J Korean Med Sci 2002; 17: 435–47.
  • 32- Gantous A, Phillips JH, Catton P, Holmberg D Distraction osteogenesis in the irradiated canine mandible. Plast Reconstr Surg 1994; 93: 164-168.
  • 33- Amir, L.R., Becking, A.G., Jovanovic, A., Perdijk, F.B.T., Everts, V. & Bronckers, A.L.J.J. Vertical distraction osteogenesis in the human mandible: a prospective morphometric study. Clinical Oral Implants Research 2006; 17: 417–425.
  • 34- Baum R and Gravallese E.M. Impact of Inflammation on the Osteoblast in Rheumatic Diseases. Curr Osteoporos Rep. 2014 March ; 12(1): 9–16.
  • 35- Consolo, U., Bertoldi, C., Zaffe, D. Clinical evaluation, radiologic and histologic analysis in mandibular alveolar distraction procedures. Preliminary study. Minerva Stomatologica 2000; 49: 475–484.
  • 36- Zaffe, D., Bertoldi, C., Palumbo, C., Consolo, U. Morphofunctional and clinical study on mandibular alveolar distraction osteogenesis. Clinical Oral Implants Research 2002; 13: 550–557.
  • 37- Chiapasco M, Lang NP, Bosshardt DD. Quality and quantity of bone following alveolar distraction osteogenesis in the human mandible. Clin.Oral Impl. Res. 2006; 17: 394–402
  • 38- Türker N, Basa S, Vural G. Evaluation of osseous regeneration in alveolar distraction osteogenesis with histological and radiological aspects, J Oral Maxillofac Surg. 2007 Apr; 65(4): 608-614.
Toplam 37 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Diş Hekimliği
Bölüm Research Article
Yazarlar

Abdulkareem Almarrawi 0000-0002-9163-6973

Yayımlanma Tarihi 31 Aralık 2020
Kabul Tarihi 30 Aralık 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 6 Sayı: 3

Kaynak Göster

APA Almarrawi, A. (2020). New Bone Formation during Horizontal Alveolar Distraction Osteogenesis. Journal of International Dental Sciences (Uluslararası Diş Hekimliği Bilimleri Dergisi), 6(3), 1-7.
AMA Almarrawi A. New Bone Formation during Horizontal Alveolar Distraction Osteogenesis. J Int Dent Sci. Aralık 2020;6(3):1-7.
Chicago Almarrawi, Abdulkareem. “New Bone Formation During Horizontal Alveolar Distraction Osteogenesis”. Journal of International Dental Sciences (Uluslararası Diş Hekimliği Bilimleri Dergisi) 6, sy. 3 (Aralık 2020): 1-7.
EndNote Almarrawi A (01 Aralık 2020) New Bone Formation during Horizontal Alveolar Distraction Osteogenesis. Journal of International Dental Sciences (Uluslararası Diş Hekimliği Bilimleri Dergisi) 6 3 1–7.
IEEE A. Almarrawi, “New Bone Formation during Horizontal Alveolar Distraction Osteogenesis”, J Int Dent Sci, c. 6, sy. 3, ss. 1–7, 2020.
ISNAD Almarrawi, Abdulkareem. “New Bone Formation During Horizontal Alveolar Distraction Osteogenesis”. Journal of International Dental Sciences (Uluslararası Diş Hekimliği Bilimleri Dergisi) 6/3 (Aralık 2020), 1-7.
JAMA Almarrawi A. New Bone Formation during Horizontal Alveolar Distraction Osteogenesis. J Int Dent Sci. 2020;6:1–7.
MLA Almarrawi, Abdulkareem. “New Bone Formation During Horizontal Alveolar Distraction Osteogenesis”. Journal of International Dental Sciences (Uluslararası Diş Hekimliği Bilimleri Dergisi), c. 6, sy. 3, 2020, ss. 1-7.
Vancouver Almarrawi A. New Bone Formation during Horizontal Alveolar Distraction Osteogenesis. J Int Dent Sci. 2020;6(3):1-7.

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