DENTAL BOTOKS UYGULAMALARI

Öz

    Botulinum toksini (BT) Clostridium Botulinum tarafından anaerobik koşullar altında üretilen en ölümcül toksinlerden biridir. BT, kolinerjik nöron sinapslarında asetilkolin salınımını bloke ettiği nöromüsküler kavşak (NMJ) üzerindeki etkisiyle kas felcine neden olduğunun öğrenilmesinden itibaren tıpta ve kozmetik alanda kullanılmaya başlanmıştır. Dünyada en yaygın olarak kullanılan BTA Botox®faciodental estetik ve terapötik amaçlara yönelik olarak diş hekimliğinde de kendine yer bulmuştur.  BT’nın terapötik ve dentofasiyal estetik kullanımda etkili ve güvenli sonuçlar elde edilmiştir. Özellikle temporo mandibuler bozukluklar, bruksizm, gummy smile gibi vakalarda radikal cerrahiye göre çok daha az invaziv olması ve yardımcı tedavi olarak fayda sağlaması nedeniyle kendine yer edinmiştir. BT'nın terapötik etkisi geçici ve nispeten güvenli olmasına rağmen, ilgili anatomi ve yüze uygulanan ilaçların sistemik ve lokal yan etkileri hakkında bilgi sahibi olmak esastır.

Anahtar Kelimeler

• Botulinum toksin A,bruksizm,diş hekimliği

APPLICATION OF DENTAL BOTOX

Öz

    Botulinum is one of the most lethal toxins known and botulinum neurotoxin produced under anaerobic conditions by Clostridium Botulinum. BT has been used in medicine and cosmetics since it has been learned that it causes muscle paralysis due to its effect on the neuromuscular junction (NMJ) where it blocks acetylcholine release in cholinergic neuron synapses. The most widely used BTA Botox® in the world has found its place in dentistry for aesthetic and therapeutic purposes such as temporomandibular disorders, bruxism, trigeminal neuralgia, oromandibular spasm, gummy smile, masseterhipertrofisi, sialorrhea. BTA injections are a much more minimally invasive method than radical surgical procedures and can be used as an adjunctive treatment. Although the therapeutic effect of CT is transient and relatively reliable, it is essential to have knowledge of the relevant anatomy and systemic and local side effects of the drugs administered to the face.

Anahtar Kelimeler

• Botulinum toxin A,bruxism,dentistry

Kaynakça

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