Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi

Özlem Demirci; Pelin Uğurlu; Nurcan Doğan; Ömer Acer; Ersin Kılınç

EN TR

Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi

Öz

Elastin prolin, valin ve glisin aminoasitlerinin yoğun olarak yer aldığı hidrofobik bölge ve alanin aminoasitinin yer aldığı çapraz bağlanma bölgesinden oluşan ve omurgalı canlıların dokularına esneklik ve hareketlilik sağlayan bir protein çeşididir. Elastinde meydana gelecek hasarlar pek çok hastalığa neden olduğundan elastin proteini üzerine çok sayıda araştırma yapılmıştır. Fakat toksik bir maddeye maruz kalan elastinde oluşacak hasarla ilgili çalışmalar literatürde sınırlı sayıdadır. Bu amaçla önemli kalıcı organik kirleticilerden biri olan Aroclor 1254’e maruz kalan elastin proteininin yapısında meydana gelen değişiklikler histopatolojik olarak incelenmiş ve oluşan hasarın konsantrasyona bağlı olduğu tespit edilmiştir.

Anahtar Kelimeler

Aroclor 1254, Elastin, Histopatoloji

Destekleyen Kurum

Dicle Üniversitesi Bilimsel Araştırma Projeleri Koordinatörlüğü

Proje Numarası

FEN.17.025

Teşekkür

Makale, Dicle Üniversitesi Bilimsel Araştırma Projeleri Koordinatörlüğü tarafından desteklenen FEN.17.025 numaralı projeden üretilmiştir.

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Yapısal Biyoloji

Bölüm

Araştırma Makalesi

Yazarlar

Özlem Demirci ^*
0000-0001-9511-2010
Türkiye

Pelin Uğurlu Bu kişi benim
0000-0002-4790-2533
Türkiye

Nurcan Doğan
0000-0002-5689-2250
Türkiye

Ömer Acer
0000-0002-5314-0475
Türkiye

Ersin Kılınç
0000-0001-5223-9919
Türkiye

Yayımlanma Tarihi

31 Aralık 2020

Gönderilme Tarihi

25 Ekim 2020

Kabul Tarihi

29 Kasım 2020

Yayımlandığı Sayı

Yıl 2020 Cilt: 9 Sayı: 2

IZ

https://izlik.org/JA39RZ82KF

APA

Demirci, Ö., Uğurlu, P., Doğan, N., Acer, Ö., & Kılınç, E. (2020). Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi. Dicle Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 9(2), 137-146. https://izlik.org/JA39RZ82KF

AMA

1.Demirci Ö, Uğurlu P, Doğan N, Acer Ö, Kılınç E. Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi. DÜFED. 2020;9(2):137-146. https://izlik.org/JA39RZ82KF

Chicago

Demirci, Özlem, Pelin Uğurlu, Nurcan Doğan, Ömer Acer, ve Ersin Kılınç. 2020. “Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi”. Dicle Üniversitesi Fen Bilimleri Enstitüsü Dergisi 9 (2): 137-46. https://izlik.org/JA39RZ82KF.

EndNote

Demirci Ö, Uğurlu P, Doğan N, Acer Ö, Kılınç E (01 Aralık 2020) Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi. Dicle Üniversitesi Fen Bilimleri Enstitüsü Dergisi 9 2 137–146.

IEEE

[1]Ö. Demirci, P. Uğurlu, N. Doğan, Ö. Acer, ve E. Kılınç, “Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi”, DÜFED, c. 9, sy 2, ss. 137–146, Ara. 2020, [çevrimiçi]. Erişim adresi: https://izlik.org/JA39RZ82KF

ISNAD

Demirci, Özlem - Uğurlu, Pelin - Doğan, Nurcan - Acer, Ömer - Kılınç, Ersin. “Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi”. Dicle Üniversitesi Fen Bilimleri Enstitüsü Dergisi 9/2 (01 Aralık 2020): 137-146. https://izlik.org/JA39RZ82KF.

JAMA

1.Demirci Ö, Uğurlu P, Doğan N, Acer Ö, Kılınç E. Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi. DÜFED. 2020;9:137–146.

MLA

Demirci, Özlem, vd. “Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi”. Dicle Üniversitesi Fen Bilimleri Enstitüsü Dergisi, c. 9, sy 2, Aralık 2020, ss. 137-46, https://izlik.org/JA39RZ82KF.

Vancouver

1.Özlem Demirci, Pelin Uğurlu, Nurcan Doğan, Ömer Acer, Ersin Kılınç. Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi. DÜFED [Internet]. 01 Aralık 2020;9(2):137-46. Erişim adresi: https://izlik.org/JA39RZ82KF

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https://doi.org/10.55007/dufed.xxxxxxx

Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi

Investigation of Changes in the Structure of Elastin Exposed to Aroclor 1254

Öz

Anahtar Kelimeler

Proje Numarası

Aroclor 1254’e Maruz Kalan Elastinin Yapısında Meydana Gelen Değişikliklerin İncelenmesi

Öz

Anahtar Kelimeler

Destekleyen Kurum

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Gönderilme Tarihi

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Yayımlandığı Sayı

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