Salmonella Serovars and Antibiotic Resistance in Chickens

Abstract

Poultry products (meat and eggs) play a key role in the global food supply as the demand for animal protein is constantly increasing. The poultry industry's implementation of intensive breeding programs to respond to this demand causes an increase in infectious diseases. Salmonellosis, which caused by bacteria of the Salmonella species, is one of the most important infectious diseases of poultry farming and is also one of the leading causes of foodborne bacterial zoonotic infections worldwide. Antibiotics are frequently used in the treatment of infections caused by Salmonella serovars in poultry farms. Unconscious and incorrect practices of antibiotics in poultry farm cause the development of antimicrobial resistance in Salmonella serovars. Particularly multidrug resistant Salmonella agents can pose a serious threat to public health as a result of the use of antibiotics in poultry. This study aimed to provide information about recent studies related to the prevalence and antibiotic resistance of Salmonella serovars.

Keywords

• Antibiotic resistance
• chicken
• Salmonella spp.

Tavuklarda Salmonella Serovarları ve Antibiyotik Direnci

Öz

Hayvansal proteine yönelik talep sürekli arttığından kanatlı hayvan ürünleri (et ve yumurta), küresel gıda arzında kilit bir rol oynamaktadır. Kanatlı endüstrisinin bu talebe cevap oluşturmak amacıyla yoğun yetiştiricilik programları uygulaması ile ilişkilendirilen infeksiyöz hastalıklarda artışa sebep olmaktadır. Bu infeksiyöz hastalıklardan birisi de Salmonella türlerinin sebep olduğu salmonellozdur. Salmonelloz, kanatlı hayvan yetiştiriciliğinin en önemli infeksiyöz hastalıklarından biri olup aynı zamanda dünya çapında gıda kaynaklı bakteriyel zoonotik infeksiyonların önde gelen nedenlerinden biridir. Kümeslerde Salmonella serovarlarının neden olduğu infeksiyonların sağaltımında sıklıkla antibiyotikler kullanılmaktadır. Kanatlı hayvan yetiştiriciliğinde yapılan bilinçsiz ve yanlış uygulamalar Salmonella serovarlarında antimikrobiyal direnç gelişimine sebep olmaktadır. Özellikle çoklu ilaca dirençli Salmonella etkenleri, kanatlı hayvanlarda antimikrobiyal ilaç kullanımının bir sonucu olarak toplum sağlığı için de ciddi bir tehdit oluşturabilmektedir. Bu derlemenin amacı, güncel araştırmalar ile Salmonella serovarlarının yaygınlığı ve antibiyotik direnci hakkında bilgiler sunmaktır.

Anahtar Kelimeler

• Antibiyotik direnci
• Salmonella spp.
• tavuk

Kaynakça

1. Tan SJ, Nordin S, Esah EM, Mahror N. (2022). Salmonella spp. in Chicken: Prevalence, Antimicrobial Resistance, and Detection Methods. Microbiol Re. 13(4):691-705.
2. Türkoğlu S, Özlü M. (2020). Kanatlı Hayvan Sektöründe Mevcut Durum ve Gelecek. Türkiye Ziraat Mühendisliği IX. Teknik Kongresi Bildiriler Kitabı-2, 153.
3. Aksakal V, Karaalp M. (2021). Kanatlı Hayvan Yetiştiriciliği Üzerine Bilimsel Araştırmalar. Iksad Yayınevi. Ankara.
4. Swelum AA, Elbestawy AR, El-Saadony MT, et al. (2021). Ways to Minimize Bacterial Infections, with Special Reference to Escherichia coli, to Cope with the First-Week Mortality in Chicks: An Updated Overview. Poult Sci. 100(5): 101039.
5. Hossain MJ, Attia Y, Ballah FM, et al. (2021). Zoonotic Significance and Antimicrobial Resistance in Salmonella in Poultry in Bangladesh for the Period of 2011–2021. Zoonoticdis. 1(1): 3-24.
6. Xing JH, Zhao W, Li QY, et al. (2021). Bacillus subtilis BSH has a Protective Effect on Salmonella Infection by Regulating the Intestinal Flora Structure in Chickens. Microb Pathog. 155: 104898.
7. Wang X, Wang H, Li T, et al. (2020). Characterization of Salmonella spp. Isolated from Chickens in Central China. BMC Vet Res. 16: 1-9.
8. Fall-Niang NK, Sambe-Ba B, Seck A, et al. (2019). Antimicrobial Resistance Profile of Salmonella Isolates in Chicken Carcasses in Dakar, Senegal. Foodborne Pathog Dis. 16(2):130-136.

9. Dieye Y, Hull DM, Wane AA, et al. (2022). Genomics of Human and Chicken Salmonella Isolates in Senegal: Broilers as a Source of Antimicrobial Resistance and Potentially Invasive Nontyphoidal Salmonellosis Infections. PLoS One, 17(3): e0266025.
10. Mellou K, Gkova M, Panagiotidou E, Tzani M, Sideroglou T, Mandilara G. (2021). Diversity and Resistance Profiles of Human Non-Typhoidal Salmonella spp. in Greece, 2003–2020. Antibiotics. 10(8): 983.
11. Kasımoglu Dogru A, Ayaz ND, Gencay YE. (2010). Serotype Identification and Antimicrobial Resistance Profiles of Salmonella spp. Isolated from Chicken Carcasses. Trop Anim Health Prod. 42, 893-897.
12. VT Nair D, Venkitanarayanan K, Kollanoor Johny A. (2018). Antibiotic-Resistant Salmonella in the Food Supply and the Potential Role of Antibiotic Alternatives for Control. Foods. 7(10): 167.
13. Wright JG, Tengelsen LA, Smith KE, et al. (2005). Multidrug-Resistant Salmonella Typhimurium in Four Animal Facilities. Emerg Infect Dis. 11(8): 1235.
14. Lai J, Wu C, Wu C, et al. (2014). Serotype Distribution and Antibiotic Resistance of Salmonella in Food-Producing Animals iShandong Province of China, 2009 and 2012. Int J Food Microbiol. 180: 30-38.
15. Khan MAS, Rahman SR. (2022). Use of Phages to Treat Antimicrobial-Resistant Salmonella Infections in Poultry. Vet Sci. 9(8): 438.
16. Ryan MP, O’Dwyer J, Adley CC. (2017). Evaluation of the Complex Nomenclature of the Clinically and Veterinary Significant Pathogen Salmonella. Biomed Res Int. 3782182: 6 pages.
17. Zhang N. (2013). A Comparison of Salmonella enterica Serovars: Are Prevalence, Virulence and Responses to Environmental Conditions Serovar or Strain Dependent, Master’s Thesis. University of Tennessee.
18. Erol İ. (2007). Gıda Hijyeni ve Mikrobiyolojisi. Pozitif Matbaacılık Ltd. Şti. Ankara.
19. Mahmoud B. (2012). Salmonella- A Dangerous Foodborne Pathogen. BoD–Books on Demand. Croatia.
20. Atasever M. (2017). Kanatlı Etlerinde Salmonella Riski. Vet Sci Pract. 12(1): 90-98.
21. Hantash T. (2022). A Quantitative Approach for Evaluating Current and Alternative Border Control of Salmonella Typhimurium and Enteritidis in İmported Frozen Poultry Meat in Respect to Human Risk of Salmonellosis, PhD Thesis. National Food Institute.
22. Gast RK, Porter Jr R.E. (2020). Salmonella Infections. in Diseases of Poultry pp 717-753.
23. Metzger N, Alvarez-Ordóñez A, Leong D, Hunt K, Jordan K. (2015). Survival of Foodborne Pathogens during Frozen Storage of Cheese Made from Artificially Inoculated Milk. Int J Dairy Technol. 95(5): 759–767.
24. Keerthirathne TP, Ross K, Fallowfield H, Whiley H. (2016). A Review of Temperature, Ph, and Other Factors that Influence the Survival of Salmonella in Mayonnaise and Other Raw Egg Products. Pathogens. 5(4): 63.
25. Grimont PA, Weill FX. (2007). Antigenic Formulae of the Salmonella Serovars. WHO Collaborating Centre for Reference and Research on Salmonella, 9:1-166.
26. Petano-Duque JM, Rueda-García V, Rondón-Barragán IS. (2023). Virulence Genes Identification in Salmonella Enterica Isolates from Humans, Crocodiles, and Poultry Farms from Two Regions in Colombia. Veterinary World, 16(10): 2096.
27. Centers for Disease Control and Prevention (CDC) (2013). The National Center for Emerging and Zoonotic Infectious Diseases.
28. Cilo BD, Karakeçili F, Güleşen R, Levent B, Özakın C, Gedikoğlu S. (2013). Salmonella Serotiplerinin Konvansiyonel ve Molekü- ler Yöntemler ile Belirlenmesi. Mikrobiyol Bul. 47: 693-701.
29. Oludairo OO, Kwaga JK, Kabir J, et al. (2022). A review on Salmonella Characteristics, Taxonomy, Nomenclature with Special Reference to Non-Typhoidal and Typhoidal Salmonellosis. Zagazig Vet J. 50(2): 161-176.
30. Metiner K, Boral, ÖB, Çelik B, et al. (2016). Antimicrobial Resistance Profiles of the Two Porcine Salmonella Typhimurium Isolates. İstanbul Univ Vet Fak Derg. 42(2): 156-160.
31. Newell DG, Koopmans M, Verhoef L, et al. (2010). Food-Borne Diseases- the Challenges of 20 Years Ago Still Persist while New Ones Continue to Emerge. Int J Food Microbiol. 139(Suppl 1):3- 15.
32. Akan M. (2008). Kanatlılarda Salmonella İnfeksiyonları ve Kontrolünde Temel Prensipler. Mektup Ankara. 6:3-4.
33. Ran X, Yang Z, Shao G, Wen X, Liu S, Ni H. (2018). Avian Salmonella Enteritidis Serovar Enteritidis with Clpp Deletion is Attenuated and Highly Immunogenic İn Chickens. Turk J Vet AnimSci. 42(4): 269-276.
34. Ata Z. (2008). Ankara Bölgesi’ndeki Tavukçuluk İşletmelerinden Salmonella spp. İzolasyonu. Doktora Tezi. Ankara Üniversitesi Sağlık Bilimleri Enstitüsü.
35. Eng SK, Pusparajah P, Mutalib NS, Ser HL, Chan KG, Lee LH. (2015). Salmonella: A Review on Pathogenesis, Epidemiology and Antibiotic Resistance. Front Life Sci. 8(3):284–293.
36. Castro-Vargas RE, Herrera-Sánchez MP, Rodríguez-Hernández R, Rondón-Barragán IS. (2020). Antibiotic Resistance in Salmonella spp. Isolated from Poultry: A Global Overview. Vet World. 13(10): 2070.
37. Authority, E. F. S. (2019). The European Union One Health 2018 Zoonoses Report. EFSA Journal. 17(12).
38. European Food Safety Authority, & European Centre for Disease Prevention and Control. (2022). The European Union One Health 2021 Zoonoses Report. EFSA Journal. 20(12): e07666
39. Ulusal Salmonella Kontrol Programı (USKP). (2018). Ulusal Salmonella Kontrol Programı Sonuç Raporu. Erişim:https://www.tarimorman.gov.tr/GKGM/Duyuru/323/UlusalSalmonella-Kontrol-Programi. Erişim Tarihi: 12.01.2024.
40. Alessiani A, Goffredo E, Mancini M, et al. (2022). Evaluation of Antimicrobial Resistance in Salmonella Strains Isolated from Food, Animal and Human Samples between 2017 and 2021 in Southern Italy. Microorganisms. 10(4): 812.
41. Gutierrez A, De J, Schneider KR. (2020). Prevalence, Concentration, and Antimicrobial Resistance Profiles of Salmonella Isolated from Florida Poultry Litter. J. Food Prot. 83(12): 2179-2186.
42. Yu X, Zhu H, Bo Y, et al. (2021). Prevalence and Antimicrobial Resistance of Salmonella Enterica Subspecies Enterica Serovar Enteritidis Isolated from Broiler Chickens in Shandong Province, China, 2013–2018. Poult Sci. 100(2): 1016-1023.
43. El-Mohsen A, El-Sherry S. (2022). Serological and Antibacterial Characteristics of Salmonella Isolates From Chickens in Assiut, Egypt. Benha Vet Med J. 41(2): 93-99.
44. Sodagari HR, Habib I, Whiddon S, et al. (2020). Occurrence and Characterization of Salmonella Isolated from Table Egg Layer Farming Environments in Western Australia and İnsights into Biosecurity and Egg Handling Practices. Pathogens. 9(1): 56.
45. Polat İ, Şen B, Onurdağ FK. (2023). Salmonella Enterica Serotypes Isolated for the First Time in Laying Hens, and Their Susceptibility to Antibiotics. Poult Sci. 103180
46. Çokal Y, Günaydın E, Goncagül G, Önat K, Gökmen TG. (2020). Salmonella Serovars and Antimicrobial Resistance Profiles in Commercial Layer Flocks. Isr J Vet Med. 75(1): 23-30.
47. Kahya Demirbilek S, Kesin Tug B, Temelli S, Carlı K, Eyigor A. (2014). Detection of Salmonella from Layer Flocks and Typing of the Isolates. Kafkas Univ Vet Fak Derg. 20(6): 939-944
48. Şık Z, Altıntaş Ö, Atıcı EG, Elitok Y, Şen S. (2022). Distribution of Salmonella Serovars of Animal Origin in Türkiye between 2015 and 2020. J Etlik Vet Microbiol. 33(2): 7-14.
49. de Mesquita Souza Saraiva M, Lim K, do Monte DFM, et al. (2022). Antimicrobial Resistance in the Globalized Food Chain: A One Health Perspective Applied to the Poultry Industry. Braz J Microbiol. 53(1): 465-486.
50. Ince SS, & Akan M. (2023). Phenotypic and Genotypic Characterization of Antimicrobial Resistance in Commonly Isolated Salmonella Serovars from Chickens. Turk J Vet Anim Sci. 47(1): 19-25.
51. World Health Organization. (2019). Critically Important Antimicrobials for Human Medicine. 6th Revision. Eri- şim: https://www.who.int/publications-detail-redirect/9789241515528. Erişim Tarihi: 13.01.2024
52. FDA- Food and Drug Administration (2018). NARMS Update: Integrated Report Summary. Erişim: https://www.fda.gov/animal-veterinary/national-antimicrobial-resistance-monitoringsystem/2018-narms-update-integrated-report-summary. Eri-şim Tarihi: 13.01.2024.
53. Gorbach SL. (2001). Antimicrobial Use in Animal Feed—Time to Stop. N Engl J Med. 345(16): 1202-1203.
54. Castello A, Piraino C, Butera G, et al. (2023). Prevalence and Antimicrobial Resistance Profiles of Salmonella spp. in Poultry Meat. Ital. J. Food Saf 12(2): 11135.
55. Li Y, Kang X, Ed-Dra A, et al. (2022). Genome-based Assessment of Antimicrobial Resistance and Virulence Potential of Isolates of Non-Pullorum/Gallinarum Salmonella Serovars Recovered from Dead Poultry in China. Microbiol Spectr. 10(4): e00965- 22.
56. Sigirci BD, Celik B, Kahraman BB, Bagcigil AF, Ak, S. (2019). Tetracycline Resis"tance of Enterobacteriaceae Isolated from Feces of Synanthropic Birds. J Exot Pet Med. 28: 13-18
57. Sigirci BD, Celik B, Halac B, et al. (2020). Antimicrobial Resistance Profiles of Escherichia Coli Isolated from Companion Birds. J King Saud Univ Sci. 32(1): 1069-1073.