Iron Metabolism and Haematological Changes in Sheep During The Periparturient Period

Abstract

This study sought to evaluate changes in plasma iron (Fe), unsaturated iron-binding capacity (UIBC), and hematocrit (Hct) levels in pregnant ewes before and after parturition. Blood samples were collected 10 days before and 10 days after birth, and concentrations of Fe, UIBC, and Hct were evaluated. The results indicated a substantial reduction in plasma iron levels postpartum (p=0.042) and a considerable elevation in UIBC levels (p=0.004). No statistically significant variation in Hct level was observed between the prepartum and postpartum periods (p=0.531). The reduction in plasma iron levels may be linked to heightened physiological requirements for iron and bleeding associated with parturition. Increased UIBC levels indicate changes in transferrin binding capacity during the postpartum period. Hct levels remained consistent postnatally, signifying the preservation of hematopoietic equilibrium.

Keywords

• Ewes
• iron
• unsaturated iron-binding capacity

Koyunlarda Periparturient Periyotta Demir Metabolizmasi ve Hematolojik Değişiklikler

Öz

Bu çalışma, gebe koyunlarda doğum öncesi ve sonrası plazma demir (Fe), doymamış demir bağlama kapasitesi (UIBC) ve hematokrit (Hct) seviyelerindeki değişimleri değerlendirmek amacıyla gerçekleştirilmiştir. Çalışmada, doğumdan 10 gün önce ve doğumdan 10 gün sonra alınan kan örneklerinde Fe, UIBC ve Hct düzeyleri analiz edilmiştir. Elde edilen bulgular, doğum sonrası dönemde plazma Fe seviyelerinin anlamlı bir şekilde azaldığını (p=0.0425), buna karşılık UIBC seviyelerinin belirgin bir artış gösterdiğini (p=0.0004) ortaya koymuştur. Hematokrit seviyelerinde ise doğum öncesi ve sonrası dönemler arasında istatistiksel olarak anlamlı bir fark bulunmamıştır (p=0.531). Plazma Fe seviyelerindeki azalma, doğum sırasında meydana gelen kan kaybı ve artan fizyolojik demir ihtiyacı ile ilişkilendirilebilir. UIBC seviyelerindeki artış ise doğum sonrası transferrin bağlanma kapasitesindeki değişiklikleri yansıtmaktadır. Hct seviyelerindeki stabil durum, doğum sonrası hematopoetik dengenin korunduğunu göstermektedir.

Anahtar Kelimeler

• Demir
• doymamış demir bağlama kapasitesi
• koyun

Kaynakça

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