Yıl 2019, Cilt 9 , Sayı 2, Sayfalar 95 - 101 2019-05-31

Effect of Delayed Umbilical Cord Clamping on Newborn Health
Geciktirilmiş Umbilikal Kordon Klemplemenin Yenidoğan Sağlığına Etkisi

Gonca KARATAŞ BARAN [1] , Sevil ŞAHİN [2]


It is defined that transfer from blood placenta to baby as "placental transfusion" during the time of birth and until the umbilical cord is clamped. Early cord clamping is an avoidable, unphysiologic intervention that prevents the natural process of placental transfusion. Delayed cord clamping provides blood transfer from the placenta to the newborn at birth. 25-60% of fetal placental total blood volume and 60% of fetal red blood cells are present in the placental circulation and this blood is rich in part of hematopoietic stem cells. Placental transfusion may have significant effects on the successful postnatal physiological transition of the newborn. Baby’s birth, after birth with enough blood volume significantly affects the health and well-being of his later life. Recently, a number of studies have been conducted on the importance of providing placental transfusion to the newborn. There is no consensus on the timing of ideal cord clamping and terminology of cord clamping, as evidenced by the benefits of delayed cord clamping with evidence. Health care providers have still applied early cord clamping and there might be differences between institutions and individuals at clamping time. Cord clamping application should be standardized and national guidelines should be developed by studying to determine the optimal cord clamping time.

Doğum sırasında bebeğin doğumu ile umbilikal kordonun klemplenmesine kadar geçen sürede kanın plasentadan bebeğe transferi “plasental transfüzyon” olarak tanımlanmaktadır. Erken kordon klempleme plasental transfüzyonun doğal sürecini engelleyen fizyolojik olmayan bir uygulamadır. Geciktirilmiş kordon klempleme doğumda plasentadan yenidoğana kan transferini sağlar. Fetoplasental total kan volümünün %25-60’ı ve fetal kırmızı kan hücrelerinin %60’ı plasental sirkülasyonda bulunur ve bu kan hematopoetik kök hücreleri yönünden zengindir. Plasental transfüzyon, yenidoğanın başarılı postnatal fizyolojik geçişinde önemli etkilere sahip olabilmektedir. Bebeğin doğum sonrası yeterli kan hacmi ile doğmuş olması sonraki yaşamındaki sağlık ve iyilik halini önemli ölçüde etkilemektedir. Son zamanlarda, yenidoğana plasental transfüzyon sağlanmasının önemi konusunda bir dizi çalışma yapılmıştır. Kanıtlar ile geç kordon klemplemenin yararları ortaya konulmuş olmakla birlikte kordon klempleme ile ilgili terminaloji ve ideal kordon klempleme zamanı konusunda fikir birliği bulunmamaktadır. Sağlık bakım sağlayıcıları hala erken kordon klemplemeyi uygulamakta, klempleme zamanında kurumlar ve kişiler arası farklılıklar bulunabilmektedir. Optimal kordon klempleme zamanını belirlemeye yönelik çalışmalar yapılarak kordon klempleme uygulaması standardize edilmeli ve ulusal kılavuzlar geliştirilmelidir.

  • 1. Tiryaki Ö, Doğu Ö, Hafızoğlu T. Plasenta ve umbilikal kordon hakkında ebelere verilen eğitimin değerlendirilmesi. Perinatoloji Dergisi. 2017; 25(2): 64-70.
  • 2. Rabe H, Diaz-Rossello JL, Duley L, Dowswell T. Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes. Cochrane Database Syst Rev. 2012; (8): CD003248. doi:10.1002/14651858.CD003248.pub3.
  • 3. Mcdonald SJ, Middleton P, Dowswell T, Morris PS. Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes. Cochrane Database Syst Rev. 2013; (7): CD004074. doi: 10.1002/14651858.CD004074.pub3.
  • 4. Kim AJ, Warren JB. Optimal timing of umbilical cord clamping: The debate settled? Part 1 of 2: History, rationale, influencing factors and concerns. Neo Reviews. 2015; 16: e263. doi: 10.1542/neo.16-5-e263.
  • 5. Garabedian C, Rakza T, Drumez E, Poleszczuk M, Ghesquiere L, Wibaut B, et al. Benefits of delayed cord clamping in red blood cell alloimmunization. Pediatrics. 2016; 137(3): e20153236. doi: 10.1542/peds.2015-3236.
  • 6. who.int [Internet]. World Health Organization (WHO) Guideline: Delayed umbilical cord clamping for improved maternal and infant health and nutrition outcomes. Geneva: World Health Organization; 2014 [Updated: 2014; Cited: 05.03.2018]. Available from: http://apps.who.int/iris/bitstream/handle/10665/148793/9789241508209_eng.pdf.%2015%20%20ubat%202018;jsessionid=3FE6250A2D7FBC7927383258AA4CC775?sequence=1.
  • 7. aap.org [Internet]. American Academy of Pediatrics/ American Heart Association, Summary of the revised neonatal resuscitation guidelines [Updated: 2015; Cited: 02.03. 2018]. Available from: https://www.aap.org/en-us/Documents/nrp_newsletter _2015_fallwinter.pdf.
  • 8. rcog.org.uk [Internet]. Royal College of Obstetricians and Gynaecologists, Clamping of the umbilical cord and placental transfusion [Updated: 2015; Cited: 02.03.2018]. Available from: https://www.rcog.org.uk /en/guidelines-research-services/guidelines/sip14/.
  • 9. midwife.org [Internet]. American College of Nurse Midwives (ACNM), Delayed umbilical cord clamping. Position statement [Updated: 2014; Cited: 02.03. 2018]. Available from: http://www.midwife. org/ACNM/files/ACNMLibraryData/UPLOADFILENAME/000000000290/Delayed-Umbilical-Cord-Clamping-May-2014.pdf.
  • 10. neonatology.org.tr [Internet]. Doğum salonu yönetimi rehberi [Son güncelleme tarihi: 2016; Erişim tarihi: 02.03.2018]. Erişim adresi: http://www.neonatology.org.tr/wcontent/uploads/2016/12/dogum_odasi_yonetimi.pdf.
  • 11. acog.org [Internet]. American College of Obstetricians and Gynecologists (ACOG), Committee opinion, Number 684 [Internet]. Washington: American College of Obstetricians and Gynecologists; 2017 [Updated: 2017; Cited: 02.03.2018]. Available from: https://www.acog.org/-/media/Committee-Opinions/Committee-on-Obstetric-Practice/co687.pdf.
  • 12. Mercer JS, Erickson-Owens DA, Vohr BR, Tucker RJ, Parker AB, Oh W, et al. Effects of placental transfusion on neonatal and 18 month outcomes in preterm infants: A randomized controlled trial. J Pediatr. 2016; 168: 50-5. e1. doi: 10.1016/j.jpeds. 2015.09.068.
  • 13. KC A, Målqvist M, Rana N, Ranneberg LJ, Andersson O. Effect of timing of umbilical cord clamping on anaemia at 8 and 12 months and later neurodevelopment in late pre-term and term infants; a facility-based, randomized controlled trial in Nepal. BMC Pediatrics. 2016; 16: 35. doi: 10.1186/s12887-016-0576-z.
  • 14. ICEA. Delyed cord clamping [Internet]. Morrisville: International Childbirth Education Association, 2015 [Updated: 2015; Cited: 18.04.2018]. Available from: http://icea.org/wp-content/uploads/2016/01/Delayed_ Cord_Clamping_PP.pdf.
  • 15. who.int [Internet]. World Health Organization (WHO), Recommendations for the prevention and treatment of postpartum haemorrhage. Geneva: World Health Organization; 2012 [Updated: 2012; Cited: 05.03.2018]. Available from: http://apps.who.int/iris/ bitstream/10665/75411/1/9789241548502_eng.pdf?ua=1&ua=1.
  • 16. Uwins C, Hutchon DJR. Delayed umbilical cord clamping after childbirth: Potential benefits to baby’s health. Pediatric Health, Medicine and Therapeutics. 2014; 2014(5): 161-71
  • 17. Katheria AC, Lakshminrusimha S, Rabe H, Mcadams R, Mercer JS. Placental transfusion: A Review. Journal of Perinatology. 2017; 37(2): 105-11. doi:10.1038/jp.2016.151.
  • 18. Madhavanprabhakaran GK, Wittmann AL, Vaidyanathan G, Aldughaishi T, Thomas DS. Knowledge and practice of umbilical cord clamping among maternity care providers. Journal of Midwifery and Reproductive Health. 2018; 6(3): 1311-8. doi: 10.22038/JMRH.2018.23553.1252.
  • 19. Jelin AC, Kuppermann M, Erickson K, Clyman R, Schulkin J. Obstetricians’ attitudes and beliefs regarding umbilical cord clamping. The Journal of Maternal-Fetal & Neonatal Medicine. 2014; 27(14): 1457-61. doi: 10.3109/14767058.2013.864275.
  • 20. Andersson O, Hellstrom-Westas L, Andersson D, Domellof M. Effect of delayed versus early umbilical cord clamping on neonatal outcomes and iron status at 4 months: A randomised controlled trial. BMJ. 2011; 343: d7157. doi: 10.1136/bmj.d7157.
  • 21. Van Rheenen P, De Moor L, Eschbach S, De Grooth H, Brabin B. Delayed cord clamping and haemoglobin levels in infancy: A randomised controlled trial in term babies. Tropical Medicine and International Health. 2007; 12(5): 603-15.
  • 22. Mercer J, Erickson-Owens DA, Collins J, Barcelos MO, Parker AB, Padbury JF. Effects of delayed cord clamping on residual placental blood volume, hemoglobin and bilirubin levels in term infants: A randomized controlled trial. Journal of Perinatology. 2017; 37(3): 260-4. doi:10.1038/jp.2016.222.
  • 23. Vain NE, Satragno DS, Gorenstein AN, Gordillo JE, Berazategui JP, Alda MG, et al. Effect of gravity on volume of placental transfusion: A multicentre, randomised, non-inferiority trial. Lancet. 2014; 384(9939): 235-40. doi:10.1097/01.aoa.0000469493. 05128.ba.
  • 24. who.int [Internet]. World Health Organization (WHO), Delayed clamping of the umbilical cord to reduce infant anaemia. Geneva: World Health Organization; 2013 [Updated: 2013; Cited: 05.03.2018]. Available from: http://apps.who.int/iris /bitstream/10665/120074/1/WHO_RHR_14.19_eng.pdf.
  • 25. Farrar D, Airey R, Law GR, Tuffnell D, Cattle B, Duley L. Measuring placental transfusion for term births: Weighing babies with cord intact. BJOG. 2011; 118(1): 70-5. doi: 10.1111/j.1471-0528.2010. 02781.x.
  • 26. who.int [Internet]. World Health Organization (WHO), Worldwide prevalence of anaemia 1993-2005: WHO global database on anaemia. Geneva: World Health Organization; 2008 [Updated: 2008; Cited: 05.03.2018]. Available from: http://apps. who.int/iris/bitstream/10665/43894/1/9789241596657_eng.pdf.
  • 27. Çakır Eren E. Çocuklarda yaş gruplarına ve cinslerine göre anemi ve demir eksikliği anemisi sıklığının incelenmesi [Uzmanlık Tezi]. İstanbul: Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi, Aile Hekimliği Anabilim Dalı; 2008.
  • 28. Andersson O, Lindquist B, Lindgren M, Stjernqvist K, Domellöf M, Hellströmwestas L. Effect of delayed cord clamping on neurodevelopment at 4 years of age: A randomized clinical trial. JAMA Pediatr. 2015; 169(7): 631-8. doi: 10.1001/jamapediatrics.2015 .0358.
  • 29. Bolstridge J, Bell T, Dean B, Mackley A, Moore G, Swift C, et al. A quality improvement initiative for delayed for delayed umbilical cord clamping in very low-birthweight infants. BMC Pediatr. 2016; 16: 155. doi 10.1186/s12887-016-0692-9.
  • 30. Ceriani Cernadas JM. Timing of umbilical cord clamping of term infants. Arch Argent Pediatr. 2017; 115(2): 188-94. doi: 10.5546/aap.2017.eng.188.
  • 31. Bhatt S, Alison BJ, Wallace EM, Crossley KJ, Gill AW, Kluckow M, et al. Delaying cord clamping until ventilation onset improves cardiovascular function at birth in preterm lambs. J Physiol. 2013; 591: 2113-26. doi: 10.1113/jphysiol.2012.250084.
  • 32. Ceriani Cernadas JM. Stem cell transfer in newborn infants through placental transfusion via delayed umbilical cord clamping. Arch Argent Pediatr. 2016; 114(6): 498-9. doi: 10.5546/aap.2016.eng.498.
  • 33. Kanmaz Kutman HG, Oğuz Ş, Uraş N. Altın dakikalar: Prematüre bebeğin doğum salonunda yönetimi. Jinekoloji - Obstetrik ve Neonatoloji Tıp Dergisi. 2015; 12(4): 162-6.
  • 34. Katheria AC, Wozniak M, Harari D, Arnell K, Petruzzelli D, Finer NF. Measuring cardiac changes using electrical Impedance during delayed cord clamping: A feasibility trial. Maternal Health, Neonatology, and Perinatology. 2015; 1: 15. doi:10.1186/s40748-015-0016-3.
  • 35. Backes CH, Huang H, Iams JD, Bauer JA, Giannone PJ. Timing of umbilical cord clamping among infants born at 22 through 27 weeks’ gestation. J Perinatol. 2016; 36(1): 35-40. doi: 10.1038/jp.2015.117.
  • 36. De Paco C, Herrera J, Garcia C, Corbalán S, Arteaga A, Pertegal M, et al. Effects of delayed cord clamping on the third stage of labour, maternal haematological parameters and acid–base status in fetuses at term. Eur J Obstet Gynecol Reprod Biol. 2016; 207: 153-6. doi: https://doi.org/10.1016/j.ejogrb.2016.10.031.
  • 37. Grace L, Duggal N, Garabedian M. Maternal safety evaluation following implementation of universal delayed cord clamping [4R]. Obstetrics & Gynecology. 2016; 127(Supp 1): 148S. doi: 10.1097/01.AOG.0000483592.63067.23.
  • 38. Ruangkit C, Leon M, Hassen K, Baker K, Poeltler D, Katheria A. Maternal bleeding complications following early versus delayed umbilical cord clamping in multiple pregnancies. BMC Pregnancy and Childbirth. 2018; 18: 131. doi: https://doi.org /10.1186/s12884-018-1781-6.
  • 39. Thomas MR, Yoxall CW, Weeks AD, Duley L. Providing newborn resuscitation at the mother’s bedside: Assessing the safety, usability and acceptability of a mobile trolley. BMC Pediatr. 2014; 14: 135. doi: 10.1186/1471-2431-14-135.
  • 40. Hutchon D. Evolution of neonatal resuscitation with intact placental circulation. Infant. 2014; 10(2): 58-61.
  • 41. Boere I, Smit M, Roest AA, Lopriore E, van Lith JM, te Pas AB. Current practice of cord clamping in the Netherlands: A questionnaire study. Neonatology. 2015; 107(1): 50-5. doi: 10.1159/000365836.
  • 42. Downey C, Bewley S. Historical perspectives on umbilical cord clamping and neonatal transition. Candice. J R Soc Med. 2012; 105: 325-9. doi:10.1258 /jrsm.2012.11031.
  • 43. Lundberg C, Øian P, Klingenberg C. Umbilical cord clamping at birth-practice in Norwegian maternity wards. Tidsskr Nor Laegeforen. 2013; 133(22): 2369-73. doi:10.4045/tidsskr.12.0707.
  • 44. Stoll K, Hutton E. A survey of umbilical cord clamping practices and attitudes of Canadian maternity care providers. Canadian Journal of Midwifery Research and Practice. 2012; 11(3):18-29.
  • 45. Ononeze AB, Hutchon DJ. Attitude of obstetricians towards delayed cord clamping: A questionnaire-based study. Journal of Obstetrics and Gynecology. 2009; 29(3): 223-4.
  • 46. Ibrahim NO, Sukkarieh HH, Bustami RT, Alshammari EA, Alasmari LY, Al-Kadri HM. Current umbilical cord clamping practices and attitudes of obstetricians and midwives toward delayed cord clamping in Saudi Arabia. Ann Saudi Med. 2017; 37(3): 216-24. doi: 10.5144/0256-4947.2017.216.
  • 47. Downey C, Bewley S. Childbirth practitioners’ attitudes to third stage management. British Journal of Midwifery. 2013; 18(9): 576-82. doi: https://doi.org/10.12968/bjom.2010.18.9.78066.
Birincil Dil tr
Konular Sağlık Bilimleri ve Hizmetleri
Bölüm Derlemeler
Yazarlar

Orcid: 0000-0002-7996-6144
Yazar: Gonca KARATAŞ BARAN
Kurum: ANKARA YILDIRIM BEYAZIT ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ ENSTİTÜSÜ
Ülke: Turkey


Orcid: 0000-0001-7089-6648
Yazar: Sevil ŞAHİN (Sorumlu Yazar)
Kurum: ANKARA YILDIRIM BEYAZIT ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ FAKÜLTESİ, HEMŞİRELİK BÖLÜMÜ
Ülke: Turkey


Tarihler

Yayımlanma Tarihi : 31 Mayıs 2019

Bibtex @derleme { duzcesbed451791, journal = {Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi}, issn = {}, eissn = {2146-443X}, address = {}, publisher = {Düzce Üniversitesi}, year = {2019}, volume = {9}, pages = {95 - 101}, doi = {10.33631/duzcesbed.451791}, title = {Geciktirilmiş Umbilikal Kordon Klemplemenin Yenidoğan Sağlığına Etkisi}, key = {cite}, author = {KARATAŞ BARAN, Gonca and ŞAHİN, Sevil} }
APA KARATAŞ BARAN, G , ŞAHİN, S . (2019). Geciktirilmiş Umbilikal Kordon Klemplemenin Yenidoğan Sağlığına Etkisi. Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi , 9 (2) , 95-101 . DOI: 10.33631/duzcesbed.451791
MLA KARATAŞ BARAN, G , ŞAHİN, S . "Geciktirilmiş Umbilikal Kordon Klemplemenin Yenidoğan Sağlığına Etkisi". Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 9 (2019 ): 95-101 <https://dergipark.org.tr/tr/pub/duzcesbed/issue/44468/451791>
Chicago KARATAŞ BARAN, G , ŞAHİN, S . "Geciktirilmiş Umbilikal Kordon Klemplemenin Yenidoğan Sağlığına Etkisi". Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 9 (2019 ): 95-101
RIS TY - JOUR T1 - Geciktirilmiş Umbilikal Kordon Klemplemenin Yenidoğan Sağlığına Etkisi AU - Gonca KARATAŞ BARAN , Sevil ŞAHİN Y1 - 2019 PY - 2019 N1 - doi: 10.33631/duzcesbed.451791 DO - 10.33631/duzcesbed.451791 T2 - Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi JF - Journal JO - JOR SP - 95 EP - 101 VL - 9 IS - 2 SN - -2146-443X M3 - doi: 10.33631/duzcesbed.451791 UR - https://doi.org/10.33631/duzcesbed.451791 Y2 - 2018 ER -
EndNote %0 Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi Geciktirilmiş Umbilikal Kordon Klemplemenin Yenidoğan Sağlığına Etkisi %A Gonca KARATAŞ BARAN , Sevil ŞAHİN %T Geciktirilmiş Umbilikal Kordon Klemplemenin Yenidoğan Sağlığına Etkisi %D 2019 %J Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi %P -2146-443X %V 9 %N 2 %R doi: 10.33631/duzcesbed.451791 %U 10.33631/duzcesbed.451791
ISNAD KARATAŞ BARAN, Gonca , ŞAHİN, Sevil . "Geciktirilmiş Umbilikal Kordon Klemplemenin Yenidoğan Sağlığına Etkisi". Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 9 / 2 (Mayıs 2019): 95-101 . https://doi.org/10.33631/duzcesbed.451791
AMA KARATAŞ BARAN G , ŞAHİN S . Geciktirilmiş Umbilikal Kordon Klemplemenin Yenidoğan Sağlığına Etkisi. DÜ Sağlık Bil Enst Derg. 2019; 9(2): 95-101.
Vancouver KARATAŞ BARAN G , ŞAHİN S . Geciktirilmiş Umbilikal Kordon Klemplemenin Yenidoğan Sağlığına Etkisi. Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. 2019; 9(2): 101-95.