Triglyceride Glucose Index and The Triglyceride/HDL Ratio as Predictors of Coronary Artery Disease

Yıl 2021, Cilt: 11 Sayı: 2, 235 - 241, 07.05.2021

Hatice Tolunay Serdar Fırtına

https://doi.org/10.33631/duzcesbed.882401

Öz

Aim: Triglyceride to high density lipoprotein cholesterol (TG/HDL-C) ratio and triglyceride-glucose (TyG) index are simple, reliable screening methods. It has been shown that the TyG index predicts mortality in cardiovascular diseases and the TG/HDL-C ratio predicts the severity of coronary artery disease (CAD). We planned a study to define the relationship between the SYNTAX score, which indicates the severity of CAD, and the TyG index and TG / HDL-C ratio.
Material and Methods: A total of 408 patients who underwent coronary angiography were evaluated in this study. TyG index, TG/HDL-C ratio and SYNTAX scores were calculated. Patients were grouped according to their diagnosis and SYNTAX scores. Relationships between TyG index, TG / HDL-C ratio and SYNTAX score were examined.
Results: There is a significant relationship between the TyG index and the presence of CAD (p<0.001). When the TyG index was evaluated in terms of the severity of CAD, there was a positive significant relationship between mild and severe CAD (p<0.040). While there was a significant positive correlation between TG/HDL-C ratio and the presence of CAD (p<0.001), there was no significant relationship between severity of CAD (p:0.814). There was a low level significant positive correlation in terms of TyG index between patients with unstable angina pectoris and ST-elevation myocardial infarction (p:0.046).
Conclusion: The TyG index and TG/HDL-C ratio are predictors of the presence of CAD and the TyG index also provides guidance on the severity of CAD. Standard use may be considered in addition to risk scoring in the diagnosis of CAD and planning coronary angiography.

Anahtar Kelimeler

Triglyceride-Glucose Index, Triglyceride / High Density Lipoprotein Ratio, SYNTAX Score, Coronary Artery Disease

Koroner Arter Hastalığının Öngördürücüleri Olarak Trigliserid Glikoz İndeksi ve Trigliserid / HDL Oranı

Öz

Amaç: Trigliserid / yüksek yoğunluklu lipoprotein kolesterol oranı (TG / HDL-C) ve trigliserid-glikoz (TyG) indeksi basit, güvenilir tarama yöntemleridir. TyG indeksinin kardiyovasküler hastalıklarda mortaliteyi öngördüğü ve TG / HDL-C oranının koroner arter hastalığının (KAH) ciddiyetini öngördüğü gösterilmiştir. Koroner arter hastalığı ciddiyetini gösteren SYNTAX skoru ile TyG indeksi ve TG / HDL-C oranı arasındaki ilişkiyi tanımlamak için bir çalışma planladık.
Gereç ve Yöntemler: Bu çalışmada koroner anjiyografi yapılan toplam 408 hasta değerlendirildi. TyG indeksi, TG / HDL-C oranı ve SYNTAX skorları hesaplandı. Hastalar tanılarına ve SYNTAX puanlarına göre gruplandırıldı. TyG indeksi, TG / HDL-C oranı ve SYNTAX skor arası ilişki incelendi.
Bulgular: TyG indeksi ile KAH varlığı arasında anlamlı bir ilişki vardır (p <0,001). TyG indeksi KAH şiddeti açısından değerlendirildiğinde hafif ve şiddetli KAH arasında pozitif yönde anlamlı ilişki vardı (p <0,040). TG / HDL-K oranı ile KAH varlığı arasında anlamlı pozitif korelasyon varken (p <0,001), KAH şiddeti arasında anlamlı bir ilişki yoktu (p: 0,814). Kararsız angina pektorisli hastalar ile ST elevasyonlu miyokard infarktüsü arasında TyG indeksi açısından düşük düzeyde anlamlı pozitif korelasyon vardı (p: 0.046).
Sonuç: TyG indeksi ve TG / HDL-C oranı, KAH varlığının öngörücüleridir ve TyG indeksi, KAH'ı ciddiyeti hakkında da yol gösterir. KAH tanısında ve koroner anjiyografi planlamasında risk skorlamalarına ek olarak standart kullanımı düşünülebilir.

Anahtar Kelimeler

Trigliserid-Glikoz İndeksi, Trigliserit / Yüksek Yoğunluklu Lipoprotein Oranı, SYNTAX Skoru, Koroner Arter Hastalığı

Kaynakça

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