Clinical Presentation and Frequency of Klatskin Tumor; A Single-Center Retrospective Study

Year 2021, Volume: 2 Issue: 3, 197 - 202, 02.10.2021

Erkan Çakmak , Nevzat Gözel

Abstract

Clinical Presentation and Frequency of Klatskin Tumor; A Single-Center Retrospective Study
Abstract
Objective: Klatskin tumor is an epithelial bile duct tumor that originates from the main hepatic duct or the right-left intrahepatic duct and appears proximal to the opening of the cystic duct. In this study, we examined the demographic characteristics, clinical, laboratory and radiological results at the time of first presentation of patients who were diagnosed with klatskin tumor in our clinic for a period of three years.
Materials and Methods: For the study; 16 patients who were hospitalized at Internal Medicine Clinic between June 1, 2015-May 1, 2018 were diagnosed with Klatskin tumor were included retrospectively. Clinical, laboratory and radiological data of patients were analyzed.
Results: 16 patients in the study, 10 were male, 6 were female. Average age was 62.30 for males, 65.33 for females. The most common symptoms respectively jaundice, itching, abdominal pain, anorexia and weakness. Among the laboratory tests, the average of some values; AST:141.31 IU/L, ALT:156.18 IU /L, ALP:692.07 IU/L, GGT:622.14 IU/L, T. Bilirubin:10.42 mg/dl, D. Bilirubin: 6.0 mg/dl, WBC:10.509 x103µ/L. Diagnostic ERCPs of the patients were examined; Klatskin tumor was considered in 14 patients due to stenosis in the proximal part of the common bile duct.
Conclusion: Clinical and laboratory findings in Klatskin tumors are not specific and the diagnosis is usually made in the late period because the clinical presentation of the disease is confused with many other diseases.

Keywords

Klatskin Tumor, Cholangiocharcinoma, ERCP, Clinichal Presentation

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