Submission of a paper will be taken to imply that it has not previously been published and that it is not being considered for publication elsewhere. Decision as to publication of papers submitted to the Experimental and Applied Medical Science will be based on the opinion of the Editorial Board as to the significance and originality of the work.

Manuscripts should be prepared electronically using an appropriate Office Word compatible text-processing package, formatted for A4 size, double-spaced throughout, and using a Times New Roman 12 point font. Articles must be written in English. Abstracts must be written in both Turkish and English. Text should flush left, and not be justified. Words should not be hyphenated. Pages should be numbered sequentially.

There should be a separate title page with:

a) the title
b) the authors' names
c) the laboratory of origin, with complete address of each author
d) a running title
e) the address to which proofs should be sent
f) acknowledgements

The main body of full-length paper should be divided into:

1. Abstract
2. Introduction
3. Material and Methods
4. Results
5. Discussion
6. Conclusion
7. Conflict of interest
8. Acknowledgement
9. References

In general, there are no specific word lengths for any manuscript. The general principle is that a manuscript can be as long as necessary to communicate clearly and most effectively the scientific message, but should be as short as possible to achieve a complete presentation of the information without undue repetition or redundancy.

In the Materials and Methods section, the source of all compounds, equipment or software should be identified by the full name of the supplier, city, state/country. The chemical names of any drug should precede the trade name.

Papers describing animal experiments must define species, strain, sex, age, supplier and number of animals used. An ethical statement concerning the use of animals, or the details of ethical approvals, consent and recruitment of human subjects should be clearly stated. Results and Discussion can be broken down into subsections for improving the comprehensibility. The Results should not repeat methodological details and should avoid the discussion of the data.

The results of statistical tests should be incorporated in the body of the text, typically in the Results section, rather than in figure legends. Adequate description of statistical analysis should be provided. Statistical measures of variation in the text, illustrations and tables, should be identified.

All dimensions and measurements must be specified in the metric system.

All subscripts, superscripts, Greek letters and unusual characters must be clearly identified.

In the text, abbreviations should be used consistently. Abbreviations should be defined on first use.

References should be designed in Vancouver style. Multiple authors should be separated by a comma. If there are more than three authors, after the 3rd author, "et al." should be inserted without a comma for both article and book references. If reference is made from a chapter in a book and there are many authors belonging only to this chapter, the title and chapter of the book are indicated, the first three of the chapter authors are written, and "et al." statement is added for subsequent authors.

Example: 

1. Perell KL, Nelson A, Goldman RL, et al. Fall risk assessment measures: an analytic review. The journals of gerontology Series A, Biological sciences and medical sciences. 2001;56(12):M761-6.

2. Ha H, Han C, Kim B. Can Obesity Cause Depression? A Pseudo-panel Analysis. Journal of preventive medicine and public health = Yebang Uihakhoe chi. 2017;50(4):262-7.

3. Çekmen MB, Turgut M, Türköz Y, et al. Nitrik Oksit (NO) ve Nitrik Oksit Sentaz (NOS)'ınFizyolojik ve Patolojik Özellikleri. Türkiye Klinikleri Journal of Pediatrics. 2001;10(4):226-35.

4. Parlakpınar H, Örüm MH, Acet A. Kafeik asit fenetil ester (KAFE) ve miyokardiyal iskemi reperfüzyon (Mİ/R) hasarı. İnönü Üniversitesi Sağlık Bilimleri Dergisi 2012; 1: 10-5.

5. Yıldırım AB. The effects of maternal hypothyroidism on the immunoreactivity of cytochrome p450 aromatase in the postnatal rat testes. 2015; Doctoral thesis.

6. https://hsgm.saglik.gov.tr/depo/birimler/kanserdb/istatistik/Trkiye_Kanser_statistikleri_2016.pdf (Last access date: 21.09.2020).

7. Kuran O, İstanbul, Filiz Kitabevi. Sistematik Anatomi. 1983 p. 76-9.

8. Abbas AK, Andrew H Lichtman, Shiv Pillai. Cellular and Molecular Immunology. 6th ed. Philadelphia: Saunders Elsevier; 2007 p. 121-56.

Submit illustrations as separate files, only as TIFF or EPS files, with a minimum resolution of 300dpi.

Tables of numerical data should each be typed with double spacing on separate pages numbered in sequence and in numerals, provided with a heading, and referred to in the text, as Table I, Table II, etc. Each table should have a brief but descriptive heading. Explanatory matter should be included in footnotes to the table.

We accept electronic supplementary material to support and enhance your scientific research. Supplementary files offer the author additional possibilities to publish supporting applications, movies, animation sequences, high-resolution images, background datasets, sound clips and more.

Disclosure of conflict of interest and financial support is required at the time of submission. The authors are responsible for informing the Journal of any additional conflicts of interest or financial support that may arise prior to the date of publication of their paper. All authors must individually disclose all potential conflicts of interest and financial support, whether or not directly related to the subject of their paper.