Araştırma Makalesi

Assessment of Anxiety, Depression, and Eating Disorder Symptoms Among Patients with Restless Legs Syndrome

Cilt: 9 Sayı: 1 30 Nisan 2026
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Assessment of Anxiety, Depression, and Eating Disorder Symptoms Among Patients with Restless Legs Syndrome

Öz

OBJECTIVE: Restless legs syndrome (RLS) is frequently accompanied by psychiatric symptoms such as depression, anxiety, and disordered eating behaviors. This study aimed to investigate the association between RLS severity, depression, anxiety, and the risk of eating disorders. MATERIALS and METHODS: This retrospective study included 72 patients diagnosed with RLS and 44 age- and sex-matched healthy controls. Depression, anxiety, and eating behaviors were assessed using the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Eating Attitudes Test (EAT-40), respectively. Demographic data and scale scores were compared between groups. Depression and anxiety severity categories were also analyzed.

RESULTS: BDI and BAI scores were significantly higher in the RLS group compared with the control group (p=0.008 and p=0.001, respectively). Mild, moderate, and severe depressive symptoms were more common among RLS patients. Anxiety severity was also markedly higher in the patient group, with severe anxiety observed in 37.5% of patients compared with 9.1% of controls. Although EAT-40 scores and the frequency of eating disorder risk were higher in the RLS group, the differences were not statistically significant (p=0.267). BMI was slightly higher in the patient group but did not reach statistical significance.

CONCLUSION: RLS is associated with significantly increased levels of depression and anxiety, highlighting a substantial neuropsychiatric burden in affected individuals. Although disordered eating tendencies appeared more common in RLS patients, further studies with larger samples are needed to clarify this relationship. Integrating psychiatric evaluation into the routine management of RLS may improve clinical outcomes and overall quality of life.

Anahtar Kelimeler

Destekleyen Kurum

Destekleyen kurum yok

Etik Beyan

Bu çalışma, Sakarya Üniversitesi Tıp Fakültesi Klinik Araştırmalar Etik Kurulu tarafından onaylanmıştır (tarih: 20.09.2025, karar no: 464).

Kaynakça

  1. 1. Trotti LM. Restless legs syndrome and sleep-related movement disorders. Continuum (Minneap Minn). 2017; 23: 1005-1016. doi: 10.1212/CON.0000000000000488
  2. 2. Merlino G, Valente M, Serafini A, Gigli GL. Restless legs syndrome: diagnosis, epidemiology, classification and consequences. Neurol Sci. 2007; 28(Suppl 1): S37-S46. doi: 10.1007/s10072-007-0736-x
  3. 3. Wijemanne S, Ondo W. Restless legs syndrome: clinical features, diagnosis and a practical approach to management. Pract Neurol. 2017; 17: 444-452. doi: 10.1136/practneurol-2017-001762
  4. 4. Rinaldi F, Galbiati A, Marelli S, Cusmai M, Gasperi A, Oldani A, et al. Defining the phenotype of restless legs syndrome/Willis-Ekbom disease (RLS/WED): a clinical and polysomnographic study. J Neurol. 2016; 263: 396-402. doi: 10.1007/s00415-015-7994-y
  5. 5. Patrick LR. Restless legs syndrome: pathophysiology and the role of iron and folate. Altern Med Rev. 2007; 12: 101-112.
  6. 6. Paulus W, Dowling P, Rijsman R, Stiasny-Kolster K, Trenkwalder C, de Weerd A. Pathophysiological concepts of restless legs syndrome. Mov Disord. 2007; 22: 1451-1456. doi: 10.1002/mds.21533
  7. 7. Kim TJ, Yoon JE, Park JA, Lee SK, Chu MK, Yang KI, et al. Prevalence and characteristics of restless legs syndrome in Korean adults: a study in two independent samples of the general population. Neuroepidemiology. 2019; 52: 193- 204. doi: 10.1159/000496839
  8. 8. Allen RP. Controversies and challenges in defining the etiology and pathophysiology of restless legs syndrome. Am J Med. 2007; 120(1 Suppl 1): S13-S21. doi: 10.1016/j. amjmed.2006.11.003

Ayrıntılar

Birincil Dil

İngilizce

Konular

Nöroloji ve Nöromüsküler Hastalıklar

Bölüm

Araştırma Makalesi

Erken Görünüm Tarihi

29 Nisan 2026

Yayımlanma Tarihi

30 Nisan 2026

Gönderilme Tarihi

25 Kasım 2025

Kabul Tarihi

26 Şubat 2026

Yayımlandığı Sayı

Yıl 2026 Cilt: 9 Sayı: 1

Kaynak Göster

APA
Ucaroglu Can, N. (2026). Assessment of Anxiety, Depression, and Eating Disorder Symptoms Among Patients with Restless Legs Syndrome. Ege Tıp Bilimleri Dergisi, 9(1), 1-7. https://doi.org/10.33713/egetbd.1829973
AMA
1.Ucaroglu Can N. Assessment of Anxiety, Depression, and Eating Disorder Symptoms Among Patients with Restless Legs Syndrome. AEGEAN J MED SCI. 2026;9(1):1-7. doi:10.33713/egetbd.1829973
Chicago
Ucaroglu Can, Nimet. 2026. “Assessment of Anxiety, Depression, and Eating Disorder Symptoms Among Patients with Restless Legs Syndrome”. Ege Tıp Bilimleri Dergisi 9 (1): 1-7. https://doi.org/10.33713/egetbd.1829973.
EndNote
Ucaroglu Can N (01 Nisan 2026) Assessment of Anxiety, Depression, and Eating Disorder Symptoms Among Patients with Restless Legs Syndrome. Ege Tıp Bilimleri Dergisi 9 1 1–7.
IEEE
[1]N. Ucaroglu Can, “Assessment of Anxiety, Depression, and Eating Disorder Symptoms Among Patients with Restless Legs Syndrome”, AEGEAN J MED SCI, c. 9, sy 1, ss. 1–7, Nis. 2026, doi: 10.33713/egetbd.1829973.
ISNAD
Ucaroglu Can, Nimet. “Assessment of Anxiety, Depression, and Eating Disorder Symptoms Among Patients with Restless Legs Syndrome”. Ege Tıp Bilimleri Dergisi 9/1 (01 Nisan 2026): 1-7. https://doi.org/10.33713/egetbd.1829973.
JAMA
1.Ucaroglu Can N. Assessment of Anxiety, Depression, and Eating Disorder Symptoms Among Patients with Restless Legs Syndrome. AEGEAN J MED SCI. 2026;9:1–7.
MLA
Ucaroglu Can, Nimet. “Assessment of Anxiety, Depression, and Eating Disorder Symptoms Among Patients with Restless Legs Syndrome”. Ege Tıp Bilimleri Dergisi, c. 9, sy 1, Nisan 2026, ss. 1-7, doi:10.33713/egetbd.1829973.
Vancouver
1.Nimet Ucaroglu Can. Assessment of Anxiety, Depression, and Eating Disorder Symptoms Among Patients with Restless Legs Syndrome. AEGEAN J MED SCI. 01 Nisan 2026;9(1):1-7. doi:10.33713/egetbd.1829973

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