Fatal Consequences of Lighter Gas Abuse: A Case Report

Yıl 2024, , 145 - 146, 31.12.2024

Ömer Faruk Çakıroğlu , Bahadir Taslidere , Bilal Arac

https://doi.org/10.55994/ejcc.1528175

Öz

Volatile solvent abuse among young people poses a significant public health threat due to its accessibility and fatal outcome potential. This case report presents a 22 year old otherwise healthy male who died after lighter gas abuse, which highlights the severity of inhalant abuse related outcomes.
To conclude, volatile substance abuse proves to be a significant and rising problem across the globe especially among younger populations, driven by its immediate psychoactive effects and ease of access. Lighter gas is a commonly abused inhalant which contains volatile hydrocarbons that cause central nervous system and respiratory depression, cardiac arrhythmias, myocardial infarction and pulmonary edema. The exact mechanism of death associated with butane abuse is still uncertain, however research done by Pfeiffer et al. focused on acute and chronic myocardial changes, and lung histology that was similar to that of drowned persons which is characterized by capillary endothelial vesicular transformation and the development of obstructive microangiopathy. Intense nonspecific fibrosis with the absence of coronary disease with immunohistochemical analysis confirming acute ischemia was also noticed. Fatal arrhythmia is thought to arise from the inhaled hydrocarbons or 0.5-15% butane which are suspected to increase the myocardium’s sensitivity to adrenaline, and this sudden hormonal surge is thought to be the culprit for the occurrence of fatal arrhythmia, and ventricular fibrillation like in this case.

Anahtar Kelimeler

Lighter gas intoxication, Sudden cardiac death, Volatile solvent abuse

Destekleyen Kurum

Yok

Kaynakça

• 1. Vahabzadeh M, Megarbane B. A two-decade review of butane toxicity as a substance of abuse. Basic Clin Pharmacol Toxicol. 2022;131:155–164. https://doi.org/10.1111/ bcpt.13760. Epub 2022 Jun 12.
• 2. Fuke C, Miyazaki T, Arao T, et al. A fatal case considered to be due to cardiac arrhythmia associated with butane inhalation. Leg Med. 2002;4:134–138. https:// doi.org/10.1016/s1344-6223(02)00004-4. 3. Pfeiffer H, Al Khaddam M, Brinkmann B, Köhler H, Beke J. Sudden death after isobutane sniffing. A report of two forensic cases. Int J Legal Med; 2006:168e73.
• 4. Sugie H,Sasaki Ch,Hashimoto C,Takeshita H,Nagai T,Nakamura S,et al.Three cases of sudden death due to butane or propane gas inhalation: analysis of tissues for gas components. Forensic Sci Int 2004;143:211e4.