The Antioxidant potential of ethanolic extract of edible mushroom Lycoperdon molle Pers. (Agaricomycetes)

Yıl 2019, Cilt: 7 Sayı: 3, 277 - 283, 29.10.2019

Celal Bal , Hasan Akgül , Mustafa Sevindik

https://doi.org/10.31195/ejejfs.591432

Cited By: 1

Öz

This study aims to
determine the antioxidant activity of ethanol (EtOH) extract from Lycoperdon molle Pers. mushroom
collected from Antalya (Turkey). Total antioxidant status (TAS), total oxidant status
(TOS) and the oxidative stress index (OSI) were analyzed using Rel Assay
Diagnostics kits. In addition, free radical scavenging activity was determined
using the DPPH method. As a result of the studies, TAS, TOS and OSI values of L. molle were 1.855±0.072, 2.201±0.085
and 0.119±0.008, respectively. The free radical scavenging activity of the fungus
was at a normal level in comparison to the standards used, i.e. rosmarinic and
caffeic acids. Consequently, it was determined that L. molle may be used as a source of natural antioxidants.

Anahtar Kelimeler

Lycoperdon molle, Antioxidant, Oxidant, DPPH, Oxidative stress

Kaynakça

• Akgul, H., Sevindik, M., Coban, C., Alli, H., Selamoglu, Z. (2017). New Approaches in Traditional and Complementary Alternative Medicine Practices: Auricularia auricula and Trametes versicolor. J Tradit Med Clin Natur. 6(2): 239
• Akpi, U.K., Odoh, C.K., Ideh, E.E., Adobu, U.S. (2017). Antimicrobial activity of Lycoperdon perlatum whole fruit body on common pathogenic bacteria and fungi. African Journal of Clinical and Experimental Microbiology, 18(2): 79-85.
• Bal, C., Akgul, H., Sevindik, M., Akata, I., Yumrutas, O. (2017). Determination of the anti-oxidative activities of six mushrooms. Fresenius Envir Bull., 26(10): 6246-6252.
• Barros, L, Venturini, B.A., Baptista, P., Estevinho, L.M., Ferreira, I.C. (2008). Chemical composition and biological properties of Portuguese wild mushrooms: a comprehensive study. Journal of agricultural and food chemistry, 56(10): 3856-3862.
• Béni, Z., Dékány, M., Kovács, B., Csupor-Löffler, B., Zomborszki, Z., Kerekes, E., Szekeres, A., Urbán, E., Hohmann, J., Ványolós, A. (2018). Bioactivity-guided isolation of antimicrobial and antioxidant metabolites from the mushroom Tapinella atrotomentosa. Molecules, 23(5): 1082.
• Burton, D.G.A., Matsubara, H., Ikeda, K. (2010). Pathophysiology of vascular calcification: Pivotal role of cellular senescence in vascular smooth muscle cells. Experimental gerontology, 45(11): 819-824.
• Burton, G.J., Jauniaux, E. (2011). Oxidative stress. Best practice & research Clinical obstetrics & gynaecology, 25(3): 287-299.
• Chandrasekaran, A., Idelchik, M.D.P.S., Melendez, J.A. (2017). Redox control of senescence and age-related disease. Redox biology, 11: 91-102.
• Colak, A., Camedan, Y., Faiz, O., Sesli, E., Kolcuoğlu, Y. (2009). An esterolytic activity from a wild edible mushroom, Lycoperdon perlatum. Journal of food biochemistry, 33(4): 482-499.
• De la Fuente, M., Miquel, J. (2009). An update of the oxidation-inflammation theory of aging: the involvement of the immune system in oxi-inflamm-aging. Current pharmaceutical design, 15(26), 3003.
• Durmaz, F., Sezer, E.N.Ş., Aktaş, S. (2018). Yenilebilir bir tür olan Lycoperdon utriformis Bull.’in yağ asit kompozisyonlarının gaz kromatoğrafisi (GC)’de tayin edilmesi. Mantar Dergisi, 9(1): 50-53
• Elsayed, E.A., El Enshasy, H., Wadaan, M.A., Aziz, R. (2014). Mushrooms: a potential natural source of anti-inflammatory compounds for medical applications. Mediators of inflammation 2014. doi: 10.1155/2014/805841
• Erel, O. (2004). A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clinical biochemistry, 37(4): 277- 285.
• Erel, O. (2005). A new automated colorimetric method for measuring total oxidant status. Clinical biochemistry, 38(12): 1103-1111.
• Girma, W., Tasisa, T. (2018). Application of Mushroom as Food and Medicine. Adv Biotech & Micro, 11(4): 555817.
• Gospodaryov, D., Lushchak, V. (2012). Oxidative Stress: cause and consequence of diseases. In Oxidative stress and diseases. IntechOpen.
• Hetland, G., Johnson, E., Lyberg, T., Kvalheim, G. (2011). The mushroom Agaricus blazei Murill elicits medicinal effects on tumor, infection, allergy, and inflammation through its modulation of innate immunity and amelioration of Th1/Th2 imbalance and inflammation. Advances in pharmacological sciences, 2011: doi: 10.1155/2011/157015
• Kalac, P. (2012). Chemical composition and nutritional value of European species of wild growing mushrooms. W: Mushrooms: Types, Properties and Nutrition. Andres S., Bauman (red.), N. Nova Science Pub. Inc., New York, 129-152.
• Li, Y., Bao, L., Song, B., Han, J., Li, H., Zhao, F., Liu, H. (2013). A new benzoquinone and a new benzofuran from the edible mushroom Neolentinus lepideus and their inhibitory activity in NO production inhibition assay. Food chemistry, 141(3): 1614-1618.
• Liguori, I., Russo, G., Curcio, F., Bulli, G., Aran, L., Della-Morte, D., Gargiulo, G., Testa, G., Cacciatore, F., Bonaduce, D., Abete, P. (2018). Oxidative stress, aging, and diseases. Clinical interventions in aging, 13: 757.
• Mueller, G.M., Schmit, J.P., Leacock, P.R., Buyck, B., Cifuentes, J., Desjardin, D.E., Halling, R.E., Hjortstam, K., Iturriaga, T., Larsson, K.H., Lodge, D.J., May, T.W., Minter, D., Rajchenberg, M., Redhead, S.A., Ryvarden, L., Trappe, J.M., Watling, R., Wu, Q. (2007). Global diversity and distribution of macrofungi. Biodiversity and conservation, 16(1): 37-48
• Novaković, A.R., Karaman, M.A., Matavulj, M.N., Pejin, B.M., Belović, M.M., Radusin, T.I., Ilić, N.M. (2015). An insight into in vitro bioactivity of wild-growing puffball species Lycoperdon perlatum (Pers) 1796. Food and Feed Research, 42(1): 51-58.
• Patel, S., Goyal, A. (2012). Recent developments in mushrooms as anti-cancer therapeutics: a review. 3 Biotech, 2(1): 1-15.
• Rahman, T., Hosen, I., Islam, M.T., Shekhar, H.U. (2012). Oxidative stress and human health. Advances in Bioscience and Biotechnology, 3(07): 997.
• Ren, L., Perera, C., Hemar, Y. (2012). Antitumor activity of mushroom polysaccharides: a review. Food & Function, 3(11): 1118-1130.
• Sevindik, M., Akgul, H., Akata, I., Alli, H., Selamoglu, Z. (2017). Fomitopsis pinicola in healthful dietary approach and their therapeutic potentials. Acta Alimentaria, 46(4): 464-469.
• Shen, Q., Chen, W., Yan, Z., Xie, Z. (2009). Potential pharmaceutical resources of the Qinling Mountain in central China: medicinal fungi. Frontiers of Biology in China, 4(1): 89-93.
• Shimada, K., Fujikawa, K., Yahara, K., Nakamura, T. (1992). Antioxidative properties of xanthan on the autoxidation of soybean oil in cyclodextrin emulsion. Journal of agricultural and food chemistry, 40(6): 945-948.
• Singh, P., Singh, A., D'Souza, L., Roy, U., Singh, S. (2012). Chemical constituents and antioxidant activity of the Arctic mushroom Lycoperdon molle Pers. Polar Research, 31(1): 17329.
• Soares, A., de Sá-Nakanishi, A., Bracht, A., da Costa, S., Koehnlein, E., de Souza, C., Peralta, R. (2013). Hepatoprotective effects of mushrooms. Molecules, 18(7): 7609-7630.
• Sun, J., Ng, T.B., Wang, H., Zhang, G. (2014). A novel hemagglutinin with antiproliferative activity against tumor cells from the hallucinogenic mushroom Boletus speciosus. BioMed research international, 2014: doi: 10.1155/2014/340467
• Udu-Ibiam, O.E., Ogbu, O., Ibiam, U.A., Nnachi, A.U., Agah, M.V., Ukaegbu, C.O., Chukwu, O.S., Agumah, N.B., Ogbu, K.I. (2014). Phytochemical and antioxidant analyses of selected edible mushrooms, ginger and garlic from Ebonyi State, Nigeria. IOSR Journal of Pharmacy and Biological Sciences, 9(3): 86-91.
• Yang BK, Kim GN, Jeong YT, Jeong H, Mehta P, Song CH (2008) Hypoglycemic effects of exo-biopolymers produced by five different medicinal mushrooms in STZ-induced diabetic rats. Mycobiology, 36(1): 45-49.
• Yıldız, S., Yılmaz, A., Can, Z., Tabbouche, S.A., Kılıç, A.O., Sesli, E. (2015). Some Bioactive Propertıes of Wild And Commercial Mushroom Specıes. Journal of Food and Health Science, 3(4): 161-169.
• Yılmaz, A., Yıldız, S., Kılıç, C., Can, Z. (2016). Total phenolics, flavonoids, tannin contents and antioxidant properties of Pleurotus ostreatus cultivated on different wastes and sawdust. International Journal of Secondary Metabolite, 4(1): 1-9.