Dabigatrana bağlı özofagus ülseri

Öz

Dabigatran trombin inhibisyonu yaparak antikoagülan etki gösteren bir ön ilaçtır. Rutin labovatuar takibi ve doz titrasyonu gerektirmemesi varfarine göre kullanım avantajı sağlanken, gastrointestinal sistem üzerine daha sık yan etki oluşturması önde gelen dezavantajlarındandır. Bizim vakamız, dabigatran kullanımına bağlı gelişen özofagus ülser hastasıdır.

Anahtar Kelimeler

• Dabigatran,ilaca bağlı özofageal ülser,antikoagülan etki

Dabigatran-induced esophageal ulcer

Öz

Dabigatran, which has an anticoagulant effect by inhibiting the action of thrombin, is a prodrug. An advantage of this drug over warfarin is that it does not require routine laboratory monitoring and dose adjustments. However, adverse effects on the gastrointestinal system are more common in patients using dabigatran than in patients using warfarin. In the present study, we report a case of dabigatran-induced esophageal ulcer.

Anahtar Kelimeler

• Dabigatran,drug-induced esophageal ulcer,anticoagulant effect

Kaynakça

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