Esophageal squamous papilloma

Öz

Esophageal squamous papilloma is a benign squamous epithelial polypoid tumor and is usually seen as a solitary lesion of the lower esophagus. They have a low prevalence, and about 250 cases have been reported in the literature since 1959. Chronic mucosal irritation and infection with human papilloma virus are proposed etiologies. There are no pathognomonic symptoms for the typical esophageal squamous papilloma. Our patient was a 51-yearold man who had chronic dyspeptic complaints and endoscopically detected reflux esophagitis. A 3-4 mm sized polypoid formation was seen at the 25’th cm of his esophagus during the endoscopic examination. Pathologic inspection of the biopsied specimen taken from this part of his esophagus indicated esophageal squamous papilloma.

Anahtar Kelimeler

• Esophageal squamous papilloma,Esophagus

Özofagus skuamoz papillomu

Öz

Özofagus skuamoz papillomu, genellikle alt özofagusta soliter bir lezyon olarak görülen, iyi huylu skuamoz epitelyal polipoid bir tümördür. Prevalans oranları çok düşüktür ve 1959’dan bu yana literatürde yaklaşık 250 vaka bidirilmiştir. Kronik mukozal irritasyon ve human papilloma virus enfeksiyonu suçlanan etyolojik nedenlerdir. Tipik özofagus skuamöz papillomunun hiçbir özgün semptomu yoktur. Bizim vakamız kronik dispeptik şikayetleri olan ve endoskopik olarak reflü özofajiti saptanan 51 yaşındaki erkek hasta idi. Endoskopik incelemede özofagus 25. cm’de 3-4 mm’lik polipoid oluşum izlendi. Buradan aldığımız biyopsi örneğinin patolojik inceleme sonucu özofagus skuamoz papillomu olarak geldi.

Anahtar Kelimeler

• Özofagus skuamöz papillomu,özofagus

Kaynakça

1. 1. K.H. Katsanos, D.K. Christodoulou, E.V. Tsianos. Esophageal squamous papilloma. Annals Of Gastroenterology 2005;18(4):456-457 2. Sablich, R, Benedetti, G, Bignucolo, S, Serraino, D. Squamous cell papilloma of the esophagus. Report on 35 endoscopic cases. Endoscopy 1988; 20:5. 3. Szanto, I, Szentirmay, Z, Banai, J, et al. [Squamous papilloma of the esophagus. Clinical and pathological observations based on 172 papillomas in 155 patients]. Orv Hetil 2005; 146:547. 4. Mosca, S, Manes, G, Monaco, R, et al. Squamous papilloma of the esophagus: long-term follow up. J Gastroenterol Hepatol 2001; 16:857. 5. Plachta, A. Benign tumors of the esophagus. Review of literature and report of 99 cases. Am J Gastroenterol 1962; 38:639. 6. Quitadamo, M, Benson, J. Squamous papilloma of the esophagus: a case report and review of the literature. Am J Gastroenterol 1988; 83:194. 7. Fernandez-Rodriguez, CM, Badia-Figuerola, N, Ruiz del, Arbol L, et al. Squamous papilloma of the esophagus: report of six cases with longterm follow-up in four patients. Am J Gastroenterol 1986; 81:1059. 8. Carr, NJ, Monihan, JM, Sobin, LH. Squamous cell papilloma of the esophagus: a clinicopathologic and follow-up study of 25 cases. Am J Gastroenterol 1994; 89:245. 9. Nakamura, T, Matsuyama, M, Kishimoto, H. Tumors of the esophagus and duodenum induced in mice by oral administration of N-ethyl-N’-nitro- N-nitrosoguanidine. J Natl Cancer Inst 1974; 52:519. 10. Syrjanen, KJ. HPV infections and oesophageal cancer. J Clin Pathol 2002; 55:721. 11. Chang, F, Janatuinen, E, Pikkarainen, P, et al. Esophageal squamous cell papillomas. Failure to detect human papillomavirus DNA by in situ hybridization and polymerase chain reaction. Scand J Gastroenterol 1991; 26:535. 12. Carr, NJ, Bratthauer, GL, Lichy, JH, et al. Squamous cell papillomas of the esophagus: a study of 23 lesions for human papillomavirus by in situ hybridization and the polymerase chain reaction. Hum Pathol 1994; 25:536. 13. Poljak, M, Orlowska, J, Cerar, A. Human papillomavirus infection in esophageal squamous cell papillomas: a study of 29 lesions. Anticancer Res 1995; 15:965. 14.Politoske, EJ. Squamous papilloma of the esophagus associated with the human papillomavirus. Gastroenterology 1992; 102:668. 15. Campo, MS. Papillomas and cancer in cattle. Cancer Surv 1987; 6:39.