Comparison of polyethylene glycol, sodium phosphate and sennoside for colonoscopy preparation

Abstract

Background and aim: The efficiency, cecal intubation rate and side effects of colonoscopy preparation with polyethylene glycol (PEG), sodium phosphate and sennosid were compared in this study.

Material and Methods: This study was carried out retrospectively by investigating the records of patients undergoing colonoscopy between July 2017 and March 2018.The patients were divided into 3 groups: PEG, sodium phosphate and sennoside group. Patients with dietary incompatibility, renal insufficiency, intestinal obstruction, active infection, active bleeding and who took fewer than 75% of medications were excluded from the study. Bowel preperation was evaluated in 4 groups as excellent, good, moderate and poor.

Results: The study population was consisted of 269 persons, 129 female (48%) and 140 male (52%) patients. The average age of the patients was 55 years. When all patients were examined, the excellent cleaning rate was 38%, the good cleaning rate was 17%, the moderate cleaning rate was 26% and the poor cleaning rate was 19%. The adequate cleaning rate was found 52% in the sennoside group, 50% in the sodium phosphate group and 66% in the PEG group. In this study, total cecal intubation rate was 90%. The cecal intubation rate was 100% in the PEG group, 87% in the sennoside group and 85% in the sodium phosphate group. The most common side effects in patients were nausea / vomiting (12%) and abdominal pain (9%).

Conclusion: Colonoscopy preparation with PEG is a more effective method than preparation with sennoside and sodium phosphate.

Keywords

• Polyethylene glycol,sodium phosphate,sennoside,PEG

Kolonoskopi hazırlığı için polietilen glikol, sodyum fosfat ve sennosid kullanımının karşılaştırılması

Öz

Amaç: Bu çalışmada kolonoskopi hazırlığı için kullanılan polietilen glikol (PEG), sodyum fosfat ve sennosidin etkinlikleri, çekuma ulaşma oranları ve yan etkileri karşılaştırılmıştır.

Yöntem: Bu çalışma Temmuz 2017-Mart 2018 tarihleri arasında kolonoskopi yapılan hastaların kayıtları retrospektif incelenerek yapılmıştır. Hastalar 3 gruba bölünmüştür: PEG, sodyum fosfat ve sennosid grubu. Diyet uyumsuzluğu olan, ilaçların %75’ten azını içen, renal yetmezlik, intestinal obstruksiyon, aktif enfeksiyon ve aktif kanaması olan hastalar çalışmadan dışlanmıştır. Kolon temizliği mükemmel, iyi, orta ve kötü olmak üzere 4 grupta değerlendirilmiştir.

Bulgular: Araştırma popülasyonu 129 kadın (%48) ve 140 erkek (%52)  erkek hasta olmak üzere 269 kişiden oluştu. Hastaların ortalama yaşı 55 yıldı. Tüm hastalar incelendiğinde mükemmel temizlik oranı % 38, iyi temizlik oranı %17, orta temizlik oranı %26 ve kötü temizlik oranı %19 olarak bulundu. Sennosid grubunda yeterli temizlik oranı %52, sodyum fosfat grubunda %50 ve PEG grubunda %66 olarak bulundu. Çalışmada 242 hastada çekuma ulaşıldı (%90). Çekuma ulaşma oranı PEG grubunda %100 iken sennosid grubunda %87 ve sodyum fosfat grubunda %85 olarak bulunmuştur. Hastalarda en sık görülen yan etkiler ise bulantı/kusma (%12) ve karın ağrısı idi (%9).

Sonuç: PEG ile kolonoskopi hazırlığı sennosid ve sodyum fosfat ile hazırlığa göre daha efektif bir yöntemdir.

Anahtar Kelimeler

• Polietilen glikol,sodyum fosfat,sennosid,PEG

Kaynakça

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