Cholangiocarcinoma arising in choledochal cysts: Case reports

Abstract

Choledochal cysts are congenital dilations of the biliary ducts that may be associated with intermittent biliary obstruction. If the condition goes unrecognized and uncorrected, the impaired bile outflow can lead to chronic hepatic injury, fibrosis, and ultimately, biliary cirrhosis. Although typically diagnosed in the pediatric population, as many as 20-30% of choledochal cysts can be discovered in adulthood. There is a female predominance. Unresected choledochal cyst is clearly associated with increased risk of cholangiocarcinoma. Treatment includes surgical removal of the choledochal cyst and bilioenteric anastomosis. In this article, we report two cases of cholangiocarcinoma occurring in an unresected choledochal cyst.

Keywords

• Cholangiocarcinoma, choledochal cyst, jaundice

Koledok kistlerinden kaynaklanan kolanjiokarsinom: Olgu Sunumları

Öz

Koledok kistleri safra kanallarının doğuştan dilatasyonudur ve aralıklı safra tıkanıklığına neden olabilir. Erken tanı ve tedavi edilmediğinde safra akı-mının bozulmasına; kronik karaciğer hasarı, fibrozis ve sonuçta biliyer siroza neden olabilir. Genellikle pediatrik popülasyonda tanısı konulmasına rağmen, %20-30 oranında erişkin yaş grubunda tespit edilebilir. Kadınlarda daha sık görülmektedir. Rezeke edilmeyen koledok kistlerinde kolanjiyokarsinom riski artmıştır. Tedavi koledok kistinin çıkarılması ve bilioenterik anastomozu içerir. Bu makalede rezeke edilmemiş koledok kistine bağlı geli-şen kolanjiyokarsinomlu iki olgu bildirildi.

Anahtar Kelimeler

• Kolanjiokarsinom, koledok kisti, sarılık

Kaynakça

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