Evaluation of gastrointestinal polyps according to their size, localization and histopathologic types

Abstract

Background and Aims: We aimed to document upper and lower gastrointestinal system polyps in our center according to their types. Materials and Methods:271 gastrointestinal polyps that were histopathologically diagnosed at Çankırı State Hospital during the period 2011-2012 were included in the study. Polyps were noted according to their localization and histopathologic types.Results:69.4% of the patients were males and 30.6% were females, and their mean age was 61.7 years. The mean diameter of the polyps was 8 mm. 233 of the polyps were located in the colon and the remainder in the stomach. Colonic polyps were most commonly seen in the rectum (36.2%), while gastric polyps were most commonly seen in the antrum (6.3%). Colonic polyps were most common in males, while gastric polyps were most common in females. Conclusions:In this study, in which we evaluated upper and lower gastrointestinal polyps separately, our results were found to be similar to those reported in the literature

Keywords

• Gastrointestinal polyps, histologic types, localization

Gastrointestinal poliplerin boyut, lokalizasyon ve histopatolojik tipleriyle değerlendirilmesi

Öz

Amaç:Çalışmadaki amacımız merkezimizde tanı alan üst ve alt gastrointestinal sisteme ait polipektomi materyallerinin histopatolojik tipleri ile birlikte dökümante edilmesidir. Gereç ve Yöntem:Çalışmada Çankırı Devlet Hastanesi Patoloji Laboratuvarında 2011- 2012 yılları arasında histopatolojik tanı verilen 271 adet gastrointestinal polip olgusu retrospektif olarak incelendi. Yerleşim özellikleri ve histopatolojik tiplerine göre polipler kaydedildi. Bulgular: Hastaların %69,4'ü erkek, %30,6'sı kadındı. Yaş dağılımı 2-91 yıl arasında değişmekte olup, yaş ortalaması 61,7 yıl, ortalama boyut 8 mm olarak saptandı. Gastrointestinal sistem polipleri yerleşim bölgeleri açısından değerlendirildiğinde 271 olgunun 233'ü kolon, 38'i mide yerleşimliydi. Kolon yerleşimli poliplerin büyük kısmının rektumda (%36,2), mide yerleşimli poliplerin ise büyük kısmının antrumda (%6,3) oldukları saptandı. Gastrointestinal sistem poliplerinde histopatolojik tipler açısından en büyük hasta grubunu 161 (%59,4) olgu ile tübüler adenom oluştururken, bunu 63 (%23,2) olgu ile hiperplastik polipler takip etmekteydi. Kolondaki polipler erkeklerde daha sık görülürken, mide lokalizasyonlu polipler kadınlarda daha sık saptandı. Tartışma:Üst ve alt gastrointestinal sisteme ait polipleri ayrı ayrı değerlendirdiğimiz çalışmamızda genel olarak tüm sonuçlarımızın literatür ile uyumluluk halinde olduğu görüldü

Anahtar Kelimeler

• Gastrointestinal polipler, histopatolojik tip, lokalizasyon

Kaynakça

1. Itzkowitz SH, Potack J. Colonic polyps and polyposis syndromes. In: Sleisenger MH, Fordtran JS, (Eds). Sleisenger and Fordtran’s Gastroin- testinal and Liver Disease. 8 th ed. Philedeplhia. Saunders. 2006; 2713- 36.
2. Konishi F, Morson BC. Pathology of colorectal adenomas: A colonoscop- ic survey. J Clin Pathol 1982; 35: 830-41.
3. Boland CR, Hzkowitz SH, Kim YS. Colonic polyps and gastrointestinal polyposis syndromes. Gastrointestinal disease, Sleisenger MH, Fordran JSS, Philadelphia, WB Saunders Company 1989; 2: 1483-518.
4. Oberhuber G, Stolte M. Gastric polyps: an update of their pathology and biological significance. Virchows Arch 2000; 437: 581-90.
5. Silverstein FE, Tytgat GNJ. Stomach II: Tumors and polyps, In: Silver- stein FE, Tytgat GNJ, Editors. Gastrointestinal Endoscopy, 3rd ed. Lon- don. Mosby 1997; 147-80.
6. Jain R, Chetty R. Gastric hyperplastik polyps: a review. Dig Dis Sci 2009; 54: 1839-46.
7. Morais DJ, Yamanaka A, Zeiture JM, Andreollo NA. Gastric polyps: a ret- rospective analysis of 26.000 digestive endoscopies. Arq Gastroenterol 2007; 44: 14-7.
8. Archimandritis A, Spiliadis C, Tzivras M, et al. Gastric epithelial polyps: aretrospective endoscopic study of 12974 symptomatic patients. Ital J Gatroenterol 1996; 28: 387-90.

9. Owen DA. The stomach, In: Sternberg SS, Editor. Diagnostic Surgical Pathology, 3rd ed. Philadelphia. Lippincott Williams & Wilkins 1999; 1311-47.
10. Debongnie JC. Gastric polyps. Acta Gastroenterol Belg 1999; 62: 187-9.
11. Davaris P, Petraki K, Archimandritis A, et al. Mucosal hyperplastik pol- yps of the stomach. Do they have any potential to malignancy? Pathol Res Pract 1986; 181: 385-9.
12. Hizawa K, Fuchigami T, lida M, et al. Possible neoplastic transformation within gastric hyperplastic polyp. Application of endoscopic polypec- tomy. Surg Endosc 1995; 9: 714-8.
13. Zea-Iriarte WL, Sekine I, Itsuno M, et al. Carcinoma in gastric hyperplas- tic polyps: a phenotypic study. Dig Dis Sci 1996; 41: 377-86.
14. Nakamura T, Nakano G. Histopathological classification and malignant change in gastric polyps. J Clin Pathol 1985; 38: 754-64.
15. O’Brien MJ, Winaver SJ, Zauber AG, et al. The National Polyp Study: Patient and polyp characteristics associated with high-grade dysplasia in colorectal adenomas. Gastroenterolgy 1990; 98: 371-9.
16. Muto T, Bussey HJR, Morson BC. The evolution of cancer of the colon and rectum. Cancer 1975: 36; 2251-70.
17. Williams AR, Balasoorriya BAW, Day DW. Polyp and cancer of the large bovel: A necropsy study in Liverpool. Gut 1982; 23: 835-42.
18. Vatn MH, Staisberg H. The prevalence of polyps of the large intestine in Osio: An autopsy study. Cancer 1982; 49: 819-25.
19. Granqvist S, Cabrielsson N, Sundelin P. Diminutive colonic polyps- clinical significance and managemant. Endoscopy 1979; 11: 36-42.
20. Matek W, Guggenmoos-Holzmann I, Demling L. Follow-up of patients with colorectal adenomas. Endoscopy 1985; 17: 175-81.
21. DiSario JA, Fautch PG, Mai HD, et al. Prevalence and malignant poten- tial of colorectal polyps in asymtomatic, avarage-risk men. Am J Gastro- enterol 1991; 86: 941-5.
22. Bech K, Kronborg O, Fenger C. Adenomasand hyperplastic polyps in screening studies. World J Surg 1991; 15: 7-13.
23. Lieberman DA, Smith FW. Screening for colon malignancy with colo- noscopy. Am J Gastroenterol 1991; 86: 946-51.
24. Joss JR. Nature and clinical significance of colorectal hyperlastic polyps. Semin Colon Rectal Surg 1991; 2: 246-52.
25. Altınparmak E, Sezgin O, Parlak E, Altıntaş E. Colorectal polyps ‘The Yüksek İhtisas experience’. Turk J Gastroenterol 2001; 12: 49-52.
26. Eminler AT, Sakallı M, Irak K, et al. Gastroenteroloji ünitemizdeki kolo- noskopik polipektomi sonuçlarımız. Akademik Gastroenteroloji Dergisi 2011; 10: 112-5.