Assessment of the frequency and severity of esophagitis in patients with gastroesophageal reflux

Abstract

Background and Aims: Gastroesophageal reflux patients presenting with typical symptoms are classified into two groups according to the Montreal classification as symptomatic syndromes and syndromes with esophageal injury. In our study, we aimed to identify the frequency of syndromes with esophageal injury, which include reflux esophagitis, Barrett's esophagus, peptic stricture, and esophageal adenocarcinoma, and the location and severity of esophagitis. Materials and Methods: Patients with typical reflux symptoms who were registered in the reflux outpatient clinic were evaluated. Frequency of reflux esophagitis, Barrett's esophagus, and peptic stricture together with the location and severity of esophagitis were determined in the evaluated patients. Results: In the evaluation of upper gastrointestinal endoscopy reports of 227 patients who were admitted with typical reflux symptoms to the reflux outpatient clinic of Kocaeli University Hospital, the percentage of reflux esophagitis and Barrett's esophagus were found to be 53% and 4%, respectively. Peptic stricture was seen in only one patient. Esophageal adenocarcinoma was not found. The percentages of esophagitis according to Los Angeles classification were as follows: 50% grade A, 45% Grade B, 2.5% Grade C, and 2.5% grade D. In the assessment of mucosal breaks of the distal esophagus, most were found to be at the 2, 3 and 6 o'clock positions. Conclusions: Half of the patients presenting with typical reflux symptoms have esophagitis. Ninety-five percent of patients with esophagitis are assessed as having mild esophagitis. Most of the mucosal breaks are seen at the 2, 3 and 6 o'clock positions.

Keywords

• GERD, reflux esophagitis, endoscopy

Gastroözofageal reflü hastalarında özofajit sıklığının ve şiddetinin değerlendirilmesi

Öz

Giriş ve Amaçlar: Pirozis ve regürjitasyon gibi tipik reflü semptomları ile başvuran hastalarda gastroözofageal reflü hastalığı Montreal sınıflamasına göre semptomatik sendromlar ve özofagusta zedelenmeyle giden sendromlar olmak üzere iki gruba ayrılmıştır Çalışmamızda tipik reflü semptomları ile gelen hastalarda; özofagusta zedelenmeyle giden sendromlar başlığı altındaki reflü özofajit, Barrett özofagusu, peptik striktür ve özofagusun adenokarsinomunun sıklığını, özofajitin şiddeti ve lokalizasyonunu belirlemeyi amaçladık. Gereç ve Yöntem: Reflü polikliniğinde kaydı bulunan tipik reflü semptomları ile başvuran olgular değerlendirildi. Değerlendirilen hastalarda reflü özofajit, Barrett özofagusu, peptik striktür ve özofagusun adenokarsinomunun sıklığı, özofajitin şiddeti ve lokalizasyonu belirlendi. Bulgular: Kocaeli Üniversitesi Reflü polikliniğine tipik reflü semptomları ile başvuran 227 hastanın üst gastrointestinal sistem raporları değerlendirildiğinde %53 reflü özofajit, %4 Barrett özofagus ve bir hastada ise peptik striktür saptandı. Özofagus adenokanseri saptanmadı. Reflü özofajitlerin %50'si Los Angeles grade A, %45'i grade B, %2,5 grade C, %2,5 grade D olarak bulundu. Özofagus distalindeki erozyone alanların lokalizasyonları incelendiğinde ise, en sık olarak saat 2, 3 ve 6 bölgesinde oldukları saptandı. Sonuç: Tipik reflü semptomları ile gelen hastaların yaklaşık yarısı reflü özofajitlidir. Özofajitli hastaların %95'i hafif özofajitli olarak değerlendirilmiştir. En sık erozyone alanlar ise saat 2, 3 ve 6 hizasında görülmektedir.

Anahtar Kelimeler

• GÖRH, reflü özofajit, endoskopi

Kaynakça

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