A rare cause of upper gastrointestinal bleeding in patients with cirrhosis and resected hepatocellular carcinoma: Recurrent tumor invasion into the duodenum

Yıl 2011, Cilt: 19 Sayı: 1, - , 01.04.2011

Nalan Gülşen Ünal Nevin Oruç Ömer Özütemiz Başak Doğanavşargil Oktay Tekeşin

https://doi.org/10.17940/endoskopi.74878

Öz

Hepatocellular carcinoma is the most common tumor in cirrhotic patients. The major cause of upper gastrointestinal bleeding in these patients is variceal bleeding secondary to portal hypertension. Bleeding from tumor invasion into the gastrointestinal tract is very rare, especially in hepatocellular carcinoma resected patients. We describe herein a resected hepatocellular carcinoma case who presented with massive hematemesis due to duodenal invasion of tumor recurrence.

Anahtar Kelimeler

Hepatocellular carcinoma, gastrointestinal bleeding, duodenum invasion

Rezeke hepatosellüler karsinomalı sirotik hastada nadir üst GİS kanama sebebi: Tümör nüksüne bağlı duodenum invazyonu

Öz

Hepatosellüler karsinoma sirotik karaciğerde en sık görülen tümördür. Bu hastalarda üst gastrointestinal sistem kanamalarının en sık nedeni portal hipertansiyona sekonder gelişen varis kanamalarıdır. Gastrointestinal trakta tümör invazyonuna bağlı kanama özellikle hepatosellüler karsinoma rezeke vakalarda çok seyrektir. Burada hepatosellüler karsinoma nedeniyle karaciğer rezeksiyonu uygulanmış, tümör nüksünün duodenum invazyonu bağlı masif hematemezle başvuran olgu sunulmuştur.

Anahtar Kelimeler

Hepatosellüler karsinoma, gastrointestinal kanama, duodenum invazyonu

Kaynakça

• Ramsey WH, Wu GY. Hepatocellular carcinoma: update on diagnosis and treatment. Dig Dis 1995; 13: 81-91.
• Carbonell N, Pauwels A, Serfaty L, et al. Improved survival after varice- al bleeding in patients with cirrhosis over the past two decades. Hepato- logy 2004; 40: 652-9.
• Longstreth GF. Epidemiology of hospitalization for acute upper gastro- intestinal hemorrhage: a population-based study. Am J Gastroenterol 1995; 90: 206-10.
• Lin CP, Cheng JS, Lai KH, et al. Gastrointestinal metastasis in hepatocel- lular carcinoma: radiological and endoscopic studies of 11 cases. J Gas- troenterol Hepatol 2000; 15: 536-41.
• Chen LT, Chen CY, Jan CM, et al. Gastrointestinal tract involvement in hepatocellular carcinoma: clinical, radiological and endoscopic studies. Endoscopy 1990; 22: 118-23.
• El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132: 2557-76.
• Fujii K, Nagino M, Kamiya J, et al. Complete resection of hepatocellular carcinoma with direct invasion to the stomach remnant. J Hepatobiliary Pancreat Surg 2004; 11: 441-4.